anti-ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1) Antikörper

ST6GAL1 encodes a member of glycosyltransferase family 29. Zusätzlich bieten wir Ihnen ST6GAL1 Proteine (14) und ST6GAL1 Kits (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ST6GAL1 6480 P15907
ST6GAL1 25197 P13721
ST6GAL1 20440 Q64685
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Top anti-ST6GAL1 Antikörper auf antikoerper-online.de

Showing 10 out of 160 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
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Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of CD75 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CD75 expression in HepG2 (A), HeLa (B), RAW264.7 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from RAW264.7 cells, using ST6GAL1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using ST6GAL1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded OVCA xenograft, using CD75, antibody at 1:500 dilution. WB Image Western Blot analysis of ST6GAL1 expression in transfected 293T cell line by ST6GAL1 polyclonal antibody. A: Non-transfected lysate. B: ST6GAL1 transfected lysate. 12% SDS PAGE antibody diluted at 1:500 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
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Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
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Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
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Human Kaninchen Unkonjugiert IP, ELISA, WB 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$218.90
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Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6275021 staining RAW264.7 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod ABIN6275021 at 1/100 staining Human lymph node tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
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Human Maus APC FACS, IF, IHC 250 μL Anmelden zum Anzeigen 3 bis 4 Tage
$392.62
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Am meisten referenzierte anti-ST6GAL1 Antikörper

  1. Human Polyclonal ST6GAL1 Primary Antibody für WB - ABIN1881841 : Mondal, Chandra, Mandal: Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia. in Leukemia research 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal ST6GAL1 Primary Antibody für IHC (fro), IHC (p) - ABIN535379 : Colombo, Canevali, Magnani, Rossi, Puppo, Zocchi, Poggi: Defective expression and function of the leukocyte associated Ig-like receptor 1 in B lymphocytes from systemic lupus erythematosus patients. in PLoS ONE 2012 (PubMed)

  3. Human Polyclonal ST6GAL1 Primary Antibody für IHC, WB - ABIN6148536 : Ju, Zhu, Lei, Yan, Zhu, Wang, Li, Li, Chen, Li, Wu: TTLL12 Inhibits the Activation of Cellular Antiviral Signaling through Interaction with VISA/MAVS. in Journal of immunology (Baltimore, Md. : 1950) 2017 (PubMed)

Weitere Antikörper gegen ST6GAL1 Interaktionspartner

Human ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1) Interaktionspartner

  1. High ST6GAL1 mRNA levels significantly correlated with lymphovascular invasion and shorter survival, whereas high ST6GAL1 protein expression was associated with advanced stage, distant metastasis and shorter recurrence-free intervals.

  2. High ST6Gal-I expression is associated with invasiveness and tumorigenicity of non-small cell lung cancer.

  3. Although ST6GalI overexpression increased HER2 sialylation, corresponding to decreased HER2 phosphorylation, high alpha2,6sialylation enhanced Akt and ERK phosphorylation levels compared to those in the vector cell line; ST6GalI knockdown had the opposite effects. Collectively, these results implicated a functional role of ST6GalI in promoting tumor cell progression and trastuzumab resistance.

  4. cells grown in hypoxia for several weeks displayed enriched ST6Gal-I expression, consistent with a pro-survival function. Taken together, these findings unravel a glycosylation-dependent mechanism that facilitates tumor cell adaptation to a hypoxic milieu.

  5. by restraining TNFR1 at the cell surface via sialylation, ST6Gal-I acts as a functional switch to divert signaling toward survival. These collective findings point to a novel glycosylation-dependent mechanism that regulates the cellular response to TNF and may promote cancer cell survival within TNF-rich tumor microenvironments.

  6. ST6GAL1 might be a potential target for atherosclerosis prevention and treatment.

  7. We discovered three significant associations at rs6679677 on 1p13.2 (P=6.15x10-5, OR=5.07), rs16861329 on 3q27.3 (P=2.02x10-4, OR=0.87) and rs849135 on 7p15.1 (P=6.59x10-9, OR=1.78), which suggested PTPN22, ST6GAL1 and JAZF1 as novel susceptibility genes for psoriasis in Chinese population.

  8. Suggest a crucial role for ST6Gal1 in elevating the invasiveness of pancreatic ductal adenocarcinoma cells in a fructose-responsive manner.

  9. these results indicate that ST6Gal-I plays a critical role in cell proliferation and invasion via the PI3K/Akt/GSK-3beta/beta-catenin signaling pathway during cancer progression

  10. these results indicate that ST6Gal-I might play a positive role in mediating the survival of human hepatocarcinoma cells

  11. The results demonstrate that epigenetic modulation of ST6Gal1 expression plays a key role in the glioma phenotype in vitro and that that therapeutic approaches targeting elements of the epigenetic machinery for the treatment of human glioblastoma are warranted.

  12. The data confirm that circulatory ST6Gal-1 is a negative systemic regulator of granulopoiesis

  13. Results provide evidence that ST6GAL1 contributes to drug resistance in cervical neoplasm.

  14. High ST6GAL1 expression is associated with ovarian and pancreatic Cancers.

  15. ST3Gal I and ST6Gal I have different sialic acid donor specificity.

  16. Taken together, these results indicate a dynamic change in the expression of ST6GAL1 during the CRC progression and provide a list of sialylated proteins potentially relevant to the different functions of ST6GAL1 in CRC.

  17. The results presented in this study provide an important advance by highlighting a new function for ST6Gal-I in promoting the viability of tumor cells exposed to the type of serum-depleted conditions often found in hypovascularized tumor microenvironments.

  18. High ST6GAL1 expression is associated with aging.

  19. Collectively, our data indicate that ST6GAL1 plays an important role in the regulation of pluripotency and differentiation in hPSCs.

  20. These results suggest a role for ST6Gal-I to promote the growth and invasion of osteosarcoma cells.

Cow (Bovine) ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1) Interaktionspartner

  1. increasing ST6Gal I gene expression in the bovine mammary gland culminated in involution

Mouse (Murine) ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1) Interaktionspartner

  1. Suggest a crucial role for ST6Gal1 in elevating the invasiveness of pancreatic ductal adenocarcinoma cells in a fructose-responsive manner.

  2. The data confirm that circulatory ST6Gal-1 is a negative systemic regulator of granulopoiesis

  3. Data, including data from studies using knockout mice, suggest that extracellular St6gal1 supports extrinsic sialylation, however, other sialyltransferases appear to be present in systemic circulation. Platelet activation [as demonstrated with the FeCl(3) model of mesenteric artery thrombosis] is minimally sufficient to elicit extrinsic sialylation.

  4. B-cell-specific ablation of ST6Gal1 in mice revealed that IgG sialylation can occur in the extracellular environment of the bloodstream independently of the B-cell secretory pathway. We also discovered that secreted ST6Gal1 is produced by cells lining central veins in the liver and that IgG sialylation is powered by serum-localized nucleotide sugar donor CMP-sialic acid that is at least partially derived from degranulat

  5. findings suggest that ST6GAL1 has an inhibitory role in adipogenesis through integrin-beta1 activation, providing new insights into the roles and regulation mechanisms of glycans in adipocytes during obesity

  6. this study proposes that remotely produced, rather than the endogenously expressed, ST6Gal-1 is the principal modifier of HSPC glycans for alpha2,6-sialic acids. In so doing, liver-produced ST6Gal-1 may be a potent systemic regulator of hematopoiesis.

  7. Altered levels of ST6GAL1 are responsible for changed invasive properties of Hca-F and Hca-P cells both in vitro and in vivo.

  8. Caveolin-1 up-regulates integrin alpha2,6-sialylation to promote integrin alpa5beta1-dependent hepatocarcinoma cell adhesion.

  9. these results demonstrate for the first time that caveolin-1 can up-regulate ST6Gal-I expression and further contribute to promoting mouse hepatocarcinoma cell adhesion to fibronectin by activating FAK-mediated adhesion signaling.

  10. Data indicate that the P1 promoter of the ST6Gal-1 gene is critical for Fc sialylation.

  11. the loci of disulphide linkages in ST6Gal-I differ from those in ST3Gal I, suggesting that the linkage specificity of sialyltransferase may results from significant structural differences, including the loci of disulphide linkages (ST6Gal-I)

  12. ST6Gal-I regulates macrophage apoptosis via alpha2-6 sialylation of the TNFR1 death receptor.

  13. Data show that the sialyltransferase enzymes St6gal1 and St3gal4 are responsible for the production of sialyllactose in mouse milk.

  14. circulatory ST6Gal-1, mostly of hepatic origin, limits myelopoiesis by a mechanism independent of hepatic sialylation of serum glycoproteins

  15. The data implicate ST6Gal-1 as a participant in regulating not only Th1 but also Th2 responses, and ST6Gal-1 deficiency can lead to the development of more severe allergic inflammation with excessive eosinophil production.

  16. tissue-specific alterations in sialylation and sialic acid 9-O-acetylation in knockout mice

  17. ST6Gal I sialyltransferase has a role in regulating galectin-1-induced CD45 clustering, phosphatase modulation, and T cell death

  18. Siat1deltaP1 animals can't raise liver Siat1 mRNA as inflammatory response; serum glycoprotein and B cells have normal sialylation; on exposure to S typhimurium, accumulation of neutrophils and greater burden in liver and spleen was observed.

  19. Ras oncogene induces ST6gal1 via a RalGEF-mediated signal to its housekeeping promoter.

  20. BACE1 cleaves ST6Gal I in vivo and controls the secretion of the E41 form of the ST6Gal I protein

ST6GAL1 Antigen-Profil

Protein Überblick

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.

Genbezeichner und Symbole assoziert mit ST6GAL1

  • ST6 beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) Antikörper
  • ST6 beta-galactoside alpha-2,6-sialyltransferase 1 (St6gal1) Antikörper
  • ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 (st6gal1) Antikörper
  • beta galactoside alpha 2,6 sialyltransferase 1 (St6gal1) Antikörper
  • AW742324 Antikörper
  • siat1 Antikörper
  • St6gal Antikörper
  • St6Gal-I Antikörper
  • ST6GAL1 Antikörper
  • St6galI Antikörper
  • ST6N Antikörper
  • zgc:136454 Antikörper

Bezeichner auf Proteinebene für ST6GAL1

B-cell antigen CD75 , CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase , CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1 , ST6Gal I , alpha 2,6-ST 1 , beta-galactoside alpha-2,6-sialyltransferase 1 , sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase) , ST6GalI , Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) , Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase) , beta galactoside alpha 2,6 sialyltransferase 1 , ST6 beta-galactosamide alpha-2,6-sialyltransferase 1 , St6 Gal I , sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) , Gal beta 1,4 GlcNAc alpha 2,6-sialyltransferase , sialyltransferase 1 , beta-galactoside alpha 2,6-sialyltransferase ST6Gal I , CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase , beta-galactosamide alpha-2,6-sialyltransferase I , beta-galactoside alpha-2,6-sialyltransferase , ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 , beta-galactoside alpha-2,6-sialyltransferase 1-like

GENE ID SPEZIES
6480 Homo sapiens
25197 Rattus norvegicus
282073 Bos taurus
396169 Gallus gallus
445376 Danio rerio
460922 Pan troglodytes
478668 Canis lupus familiaris
708113 Macaca mulatta
100059539 Equus caballus
100174088 Pongo abelii
100226346 Taeniopygia guttata
100302026 Sus scrofa
100408699 Callithrix jacchus
100481066 Ailuropoda melanoleuca
100599869 Nomascus leucogenys
100617174 Monodelphis domestica
20440 Mus musculus
100730025 Cavia porcellus
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