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SOX15 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Zusätzlich bieten wir Ihnen SOX15 Proteine (3) und SOX15 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal SOX15 Primary Antibody für ELISA, WB - ABIN408696
Meeson, Shi, Alexander, Williams, Allen, Jiang, Adham, Goetsch, Hammer, Garry: Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells. in The EMBO journal 2007
Increased expression of epithelial OCT4 (zeige POU5F1 Antikörper), SOX15 and TWIST1 (zeige TWIST1 Antikörper) was detected in endometriotic tissue compared to endometriosis patient endometrium. Epithelial expression of OCT4 (zeige POU5F1 Antikörper), SOX15, and TWIST1 (zeige TWIST1 Antikörper) was increased in the endometrium of endometriosis patients compared to controls.
Results indicate that the expression of SOX15 in pancreatic cancer cell lines with undetectable expression resulted in reduced viability of cancer cells both in vitro and in vivo demonstrating its tumor suppressive capability.
We established stable NT2/D1 cell lines overexpressing SOX15 (SOX15-NT2/D1), and a modified 3-(4,5-dime-thylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay showed that the SOX15-NT2/D1 cells exhibited significantly slower growth than controls
The gain of function studies indicated that sex-determining region Y (SRY (zeige SRY Antikörper))-box 15 (SOX15) activate NR5A1 (zeige NR5A1 Antikörper) gene expression.
Sox15 and Sox2 (zeige SOX2 Antikörper) have distinct roles in transcriptional control in mouse ES cells
role in increasing Hand1 (zeige HAND1 Antikörper) transcriptional activity might promote the transcription of the target gene resulting in the trophoblast giant cell differentiation in the mouse placenta
These studies demonstrate that Sox15, Fhl3 (zeige FHL3 Antikörper) and Foxk1 (zeige Foxk1 Antikörper) function to coordinately regulate the myogenic progenitor cell population and skeletal muscle regeneration.
These results suggest that the region from -297 to -8 of the Sox15 gene contains three distinct cis (zeige CISH Antikörper)-elements, and that these sequences were conserved among eutherian mammals during vertebrate evolution.
both Sox7 (zeige SOX7 Antikörper) and Sox15 are able to induce the early stages of myogenesis, but only Sox7 (zeige SOX7 Antikörper) is sufficient to initiate the formation of fully differentiated skeletal myocytes.
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
SRY (sex determining region Y)-box 20
, protein SOX-15
, SRY-box containing gene 15