anti-Ring Finger Protein 31 (RNF31) Antikörper

The protein encoded by RNF31 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Zusätzlich bieten wir Ihnen RNF31 Kits (2) und RNF31 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RNF31 55072 Q96EP0
RNF31 268749 Q924T7
RNF31 364386  
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Top anti-RNF31 Antikörper auf antikoerper-online.de

Showing 10 out of 86 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-RNF31 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Lanes:   Lane1: 50 ug hormoxia A549 lysate Lane2: 50 ug hypoxia A549 lysate Lane3: 50 ug hormoxia A549 lysate (+scrambled siRNA) Lane4: 50 ug hypoxia A549 lysate (+scrambled siRNA) Lane5: 50 ug hormoxia A549 lysate (RNF31 siRNA) Lane6: 50 ug hypoxia A549 lysate (RNF31 siRNA)  Primary Antibody Dilution:   1:800  Secondary Antibody:   Goat anti rabbit HRP   Secondary Antibody Dilution:   1:10000  Gene Name:   RNF31  Submitted by:   Markus Queisser, Northwestern University 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184814 staining (2µg/ml) of HepG2 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN184814 (0.5µg/ml) staining of JURKAT lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.84
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Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$507.83
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Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$610.50
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Hund Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 4 bis 8 Tage
$462.00
Details
Human Kaninchen Unkonjugiert WB Western Blot: HOIP/RNF31 Antibody [NBP1-55059] - Lanes: Lane1 : 50 ug hormoxia A549 lysate Lane2: 50 ug hypoxia A549 lysate Lane3: 50 ug hormoxia A549 lysate (+scrambled siRNA) Lane4: 50 ug hypoxia A549 lysate (+scrambled siRNA) Lane5: 50 ug hormoxia A549 lysate (RNF31 siRNA) Lane6: 50 ug hypoxia A549 lysate (RNF31 siRNA) Primary, Antibody Dilution: 1 : 800 Secondary Antibody: Goat anti rabbit HRP Secondary, Antibody Dilution: 1 : 10000 Gene name: RNF31. Western Blot: HOIP/RNF31 Antibody [NBP1-55059] - Reccomended Titration: 0.2 - 1 ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 34 Days
$559.35
Details
Human Kaninchen Unkonjugiert WB Western Blot at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: CCRF-CEM whole cell lysate Lane 3: Hela whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: MDA-MB-453 whole cell lysate Lane 6: MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane. Western Blot at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: CCRF-CEM whole cell lysate Lane 3: Hela whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: MDA-MB-453 whole cell lysate Lane 6: MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Maus Kaninchen Unkonjugiert WB MIXL1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the MIXL1 antibody detected the MIXL1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti RNF31/HOIP Polyclonal Antibody, Unconjugated (ABIN1387804) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$317.90
Details

Am meisten referenzierte anti-RNF31 Antikörper

  1. Cow (Bovine) Polyclonal RNF31 Primary Antibody für WB - ABIN2774753 : Kirisako, Kamei, Murata, Kato, Fukumoto, Kanie, Sano, Tokunaga, Tanaka, Iwai: A ubiquitin ligase complex assembles linear polyubiquitin chains. in The EMBO journal 2006 (PubMed)
    Show all 9 Pubmed References

  2. Human Polyclonal RNF31 Primary Antibody für ELISA, WB - ABIN249637 : Varfolomeev, Izrael-Tomasevic, Yu, Bustos, Goncharov, Belmont, Masselot, Bakalarski, Kirkpatrick, Vucic: Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment. in The Biochemical journal 2015 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal RNF31 Primary Antibody für ELISA, WB - ABIN546912 : van der Reijden, Erpelinck-Verschueren, Löwenberg, Jansen: TRIADs: a new class of proteins with a novel cysteine-rich signature. in Protein science : a publication of the Protein Society 1999 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen RNF31 Interaktionspartner

Human Ring Finger Protein 31 (RNF31) Interaktionspartner

  1. The binding of SHARPIN or HOIL-1L facilitates the E2 loading of HOIP.

  2. SPATA2 has been described as a previously unrecognized factor in the linear ubiquitin chain assembly complex-dependent signaling pathways that serves as an adaptor between HOIP and CYLD, thereby enabling recruitment of CYLD to signaling complexes.

  3. This review highlights recent discoveries on RNF31 functions in nuclear factor modifications, breast cancer progression and possible therapeutic inhibitors targeting RNF31. [review]

  4. The data reveal SPATA2 as a high-affinity binding partner of CYLD and HOIP, and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB signaling.

  5. LUBAC components control TLR3-mediated innate immunity, thereby preventing development of immunodeficiency and autoinflammation.

  6. Study found that RNF31 is cleaved under apoptosis conditions through various stimulations; findings elucidate a novel regulatory loop between cell death and the survival signal

  7. These results indicate that caspase-mediated cleavage of HOIP divides critical functional regions of HOIP, and that this regulates linear (de)ubiquitination of substrates upon apoptosis.

  8. RNF31 decreased p53 stability. RNF31 depletion caused cell cycle arrest and cisplatin-induced apoptosis in a p53-dependent manner. RNF31 associated with the p53/MDM2 complex, facilitating p53 polyubiquitination and degradation by stabilizing MDM2.

  9. This study describes a novel posttranslational regulation of the HOIP-containing linear-ubiquitin-chain assembly complex (LUBAC)-mediated linear ubiquitination that is critical for specifically directing TLR4-mediated NF-kappaB activation.

  10. These findings collectively indicated an oncogene role of RNF31 in PCa progression which can be regulated by miR-503, suggesting that RNF31 could serve as a potential prognostic biomarker and therapeutic target for PCa.

  11. we identified BCL10 as a bona fide target of BCR-induced linear ubiquitylation and demonstrated an important role of the linear ubiquitin ligase HOIP in BCR-induced phosphorylation

  12. crystal structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation

  13. human HOIP is essential for the assembly and function of LUBAC, which includes HOIL-1, and for various processes governing inflammation and immunity in both hematopoietic and nonhematopoietic cells

  14. Two rare germline polymorphisms affecting the LUBAC subunit RNF31 were identified and enriched among patients with activated B cell-like subtype of diffuse large B-cell lymphoma.

  15. RNF31, via stabilizing ESR1 levels, controls the transcription of estrogen-dependent genes linked to breast cancer cell proliferation.

  16. Phosphorylation of OTULIN prevents HOIP binding, whereas unphosphorylated OTULIN is part of the endogenous LUBAC complex.

  17. HOIP binding to OTULIN is required for the recruitment of OTULIN to the TNF receptor complex.

  18. target specificity toward NEMO is determined by multiple LUBAC components, whereas linear ubiquitin chain elongation is realized by a specific interplay between HOIP and ubiquitin.

  19. crystal structure of the catalytic core of HOIP in its apo form and in complex with ubiquitin

  20. The HOIP component of the linear ubiquitin assembly complex catalyzes the formation of M1-polyubiquitin chains in response to interleukin-1.

Mouse (Murine) Ring Finger Protein 31 (RNF31) Interaktionspartner

  1. Data show that keratinocyte-specific deletion of ubiquitin-protein ligases HOIP, HOIL-1 (E-KO) and shank-interacting protein-like 1 protein (SHARPIN) results in severe dermatitis causing postnatal lethality.

  2. results demonstrate that both HOIP and HOIL-1 are essential LUBAC components and are required for embryogenesis by preventing aberrant cell death; furthermore, they reveal that when LUBAC and caspase-8 are absent, RIPK3 prevents RIPK1 from inducing embryonic lethality by causing defects in fetal haematopoiesis

  3. SPATA2 has been described as a previously unrecognized factor in the linear ubiquitin chain assembly complex-dependent signaling pathways that serves as an adaptor between HOIP and CYLD, thereby enabling recruitment of CYLD to signaling complexes.

  4. HOIP's catalytic activity is necessary for preventing TNF-induced cell death. Hence, LUBAC and its linear-ubiquitin-forming activity are required for maintaining vascular integrity during embryogenesis by preventing TNFR1-mediated endothelial cell death.

  5. Restoration of HOIP expression reversed the defects in cellular activation and signaling. These results reveal HOIP as a key component of the CD40 signaling pathway

RNF31 Antigen-Profil

Protein Überblick

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.

Genbezeichner und Symbole assoziert mit RNF31

  • ring finger protein 31 (RNF31) Antikörper
  • ring finger protein 31 (rnf31) Antikörper
  • ring finger protein 31 (Rnf31) Antikörper
  • AL033293 Antikörper
  • BC031509 Antikörper
  • Flj10111 Antikörper
  • HOIP Antikörper
  • mFLJ00217 Antikörper
  • Paul Antikörper
  • RNF31 Antikörper
  • ZIBRA Antikörper

Bezeichner auf Proteinebene für RNF31

ring finger protein 31 , E3 ubiquitin-protein ligase RNF31 , HOIL-1-interacting protein , zinc in-between-RING-finger ubiquitin-associated domain protein , RING finger protein 31 , putative Ariadne-like ubiquitin ligase

GENE ID SPEZIES
100030741 Monodelphis domestica
100051661 Equus caballus
100556556 Anolis carolinensis
100606080 Nomascus leucogenys
55072 Homo sapiens
480259 Canis lupus familiaris
100158067 Sus scrofa
509856 Bos taurus
268749 Mus musculus
364386 Rattus norvegicus
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