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May play a role in spermatogenesis (By similarity).. Zusätzlich bieten wir Ihnen RNF114 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal RNF114 Primary Antibody für IHC (p), ELISA - ABIN565954
Bijlmakers, Kanneganti, Barker, Trembath, Capon: Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis. in Human molecular genetics 2011
Human Polyclonal RNF114 Primary Antibody für ICC, IF - ABIN4367139
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
RNF114 is a new partner of A2O involved in the regulation of NF-kappaB activity that contributes to the control of signaling pathways modulating T cell-mediated immune response.
XAF1 stimulates HIPK2-mediated Ser-46 phosphorylation of p53 and XAF1 also steps up the termination of p53-mediated cell-cycle arrest by activating ZNF313.
RNF114 over-expression had a promotion effect on T cell activation with an average 43.97% increment and the upregulatory roles showed a dose-dependent effect with 18.44% increment.
A single nucleotide plymorphism had an association with psoriasis in this Chinese Uygur population: SNP rs495337 in the gene encoding for zinc finger protein 313 (P < 0.001; OR = 0.80)
ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.).
Rare disease-associated variants in the promoter region of the RNF114 psoriasis susceptibility gene have been identified.
RNF114 regulates a positive feedback loop that enhances double-stranded RNA induced production of type I interferon.
ZNF313 is controlled at the transcriptional level, and a common mechanism controlling the basal transcription of ZNF313 gene exists.
ZNF313 is a novel psoriasis susceptibility gene.
These data suggested the potential physiological function of RNF114 in inflammation and host antiviral responses, but demonstrate complexity in the regulation of innate immunity by ubiquitin ligases.
our study uncovers that RNF114-mediated ubiquitination and degradation of TAB1 activate the NF-kappaB pathway during MZT, and thus directly link maternal clearance to early embryo development.
Present data suggests that Znf313 gene might play a fundamental role in gene transcription and regulation and relates to spermatogenesis.
May play a role in spermatogenesis (By similarity).
ring finger protein 114
, zinc finger protein 313
, RING finger protein 114
, zinc finger protein 228