Regulatory Factor X-Associated Protein Proteine (RFXAP)

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. Zusätzlich bieten wir Ihnen RFXAP Antikörper (51) und RFXAP Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RFXAP 5994 O00287
RFXAP 170767 Q8VCG9
Ratte RFXAP RFXAP 499617  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top RFXAP Proteine auf antikoerper-online.de

Showing 3 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

RFXAP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Regulatory Factor X-Associated Protein (RFXAP) Interaktionspartnern

Human Regulatory Factor X-Associated Protein (RFXAP) Interaktionspartner

  1. Data show a negative correlation between microRNA miR (zeige MLXIP Proteine)-212-3p and regulatory factor X-associated protein (RFXAP) in pancreatic cancer (PC) tissue.

  2. RFXAP(C) consists of two alpha-helices that form a V-shaped structure that packs within the RFX5 (zeige RFX5 Proteine)(N)(2) staple.

  3. Study demonstrates that coordinate loss of MHCII expression in OCI-Ly2 DLBCL cells is associated with an 11-base deletion in the cDNA encoding RFX-AP, that is required for activating MHCII transcription.

  4. The identification of nuclear import and export sites on RFX molecules provides potential targets to modulate MHC class II expression.

  5. Only the C-terminal half of the protein is conserved among vertebrates. The C-terminal third of RFXAP, with an extensive glutamine (zeige GFPT1 Proteine)-rich tract, could rescue HLA-DR, but not HLA-DQ or HLA-DP (zeige HLA-DPB1 Proteine) expression in a bare lymphocyte syndrome cell line.

  6. The transcriptional silent state of RFXAP correlated with reduced recruitment of RNA polymerase II to RFXAP chromatin in the MHC-II deficiency patient.

  7. RFXAP and RFXB (zeige RFXANK Proteine) have roles in relieving autoinhibition of RFX5 (zeige RFX5 Proteine)

  8. the interaction between RFX5 (zeige RFX5 Proteine) and RFXAP promote folding of a poorly structured region ofRFXAP, which is required for high affinity binding of RFXB (zeige RFXANK Proteine) to the RFX5 (zeige RFX5 Proteine).RFXAP complex

Mouse (Murine) Regulatory Factor X-Associated Protein (RFXAP) Interaktionspartner

  1. Invitro transcription/translation and transfection studies described here show that non-AUG (ACG) codon functions as a translation initiation codon.

RFXAP Protein Überblick

Protein Überblick

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.

Genbezeichner und Symbole assoziert mit RFXAP

  • regulatory factor X associated protein (RFXAP)
  • regulatory factor X associated protein (rfxap)
  • regulatory factor X-associated protein (Rfxap)
  • 5730495K23Rik Protein
  • RFXAP Protein

Bezeichner auf Proteinebene für RFXAP

regulatory factor X-associated protein , RFX DNA-binding complex 36 kDa subunit , RFX-associated protein

GENE ID SPEZIES
418899 Gallus gallus
540760 Bos taurus
607367 Canis lupus familiaris
694441 Macaca mulatta
100379771 Xenopus (Silurana) tropicalis
5994 Homo sapiens
170767 Mus musculus
499617 Rattus norvegicus
Ausgewählte Anbieter für RFXAP Proteine (RFXAP)
Haben Sie etwas anderes gesucht?