Rab Interacting Lysosomal Protein Proteine (RILP)

RILP encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Zusätzlich bieten wir Ihnen RILP Antikörper (19) und RILP Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RILP 83547 Q96NA2
RILP 280408 Q5ND29
Ratte RILP RILP 287531  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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RILP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Rab Interacting Lysosomal Protein (RILP) Interaktionspartnern

Human Rab Interacting Lysosomal Protein (RILP) Interaktionspartner

  1. Hepatitis C virus (HCV) modifies cellular trafficking by cleaving Rab interacting lysosomal protein (RILP), which serves to redirect ras-related protein Rab-7 (Rab7 (zeige RAB7B Proteine))-containing vesicles to a kinesin-dependent trafficking mode promoting virion secretion.

  2. RILP suppresses the invasion of breast cancer cells by interacting with RalGDS (zeige RALGDS Proteine) to inhibit its guanine nucleotide exchange factor (zeige RASGRF1 Proteine) activity for RalA (zeige rala Proteine).

  3. RILP regulates vacuolar ATPase through interaction with the V1G1 subunit

  4. VPS41 (zeige VPS41 Proteine) subunit of HOPS (zeige ALPL Proteine) complex was defined to be the major partner for interacting with RILP.

  5. RILP regulates the activity of the V-ATPase (zeige ATP6V1H Proteine) through its interaction with V1G1.

  6. RILP directly and concomitantly binds the tethering HOPS (zeige ALPL Proteine) complex and the p150(Glued (zeige DCTN1 Proteine)) subunit of the dynein motor. ORP1L then functions as a cholesterol-sensing switch controlling RILP-HOPS (zeige ALPL Proteine)-p150(Glued (zeige DCTN1 Proteine)) interactions.

  7. Unique region in RILP responsible for its specific role in regulating lysosomal morphology as well as in its interaction with Rab7 (zeige RAB7B Proteine) and Rab34 (zeige RAB34 Proteine).

  8. The crystal structure of Rab7 (zeige RAB7B Proteine)-GTP (zeige AK3 Proteine) in complex with the Rab7 (zeige RAB7B Proteine) binding domain of RILP reveals that Rab7 (zeige RAB7B Proteine) interacts with RILP specifically via two distinct areas.

  9. The data together indicate that RILP, as already demonstrated for several other Rab (zeige HRB Proteine) effector proteins, is capable of self-association, thus probably forming a homo-dimer.

  10. RILP indeed prenylated, while phosphorylation analysis showed that the two protein kinase A sites are phosphorylated.

Mouse (Murine) Rab Interacting Lysosomal Protein (RILP) Interaktionspartner

  1. The up-regulation of Rab11 (zeige RAB11A Proteine), Rab7 (zeige RAB7A Proteine), or RILP, but not its truncated form RILP-C33 (zeige CD82 Proteine), rescued LAMP2A-defective trafficking in cystinosis, whereas dominant-negative Rab11 (zeige RAB11A Proteine) or Rab7 (zeige RAB7A Proteine) impaired LAMP2A trafficking.

  2. A new mechanism by which the dynein-dynactin (zeige DCTN1 Proteine) motor complex recognizes Mreg (zeige MREG Proteine) on mature melanosomes is revealed through interaction with RILP and is involved in the centripetal movement of melanosomes.

  3. Rab36 (zeige RAB36 Proteine) mediates retrograde melanosome transport in melanocytes through interaction with RILP.

  4. CD63 (zeige CD63 Proteine), but not RILP, is recruited to the phagosomes in macrophages expressing the dominant negative form of Rab7 (zeige RAB7A Proteine).

RILP Protein Überblick

Protein Überblick

This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology.

Genbezeichner und Symbole assoziert mit RILP

  • Rab interacting lysosomal protein (RILP)
  • Rab interacting lysosomal protein S homeolog (rilp.S)
  • Rab interacting lysosomal protein (rilp)
  • Rab interacting lysosomal protein (Rilp)
  • AI835553 Protein
  • Gm857 Protein
  • MGC154468 Protein
  • RILP Protein
  • RP23-384C18.10 Protein

Bezeichner auf Proteinebene für RILP

Rab interacting lysosomal protein , rab-interacting lysosomal protein

GENE ID SPEZIES
417558 Gallus gallus
480649 Canis lupus familiaris
750412 Pan troglodytes
779264 Xenopus laevis
783642 Bos taurus
100127814 Xenopus (Silurana) tropicalis
83547 Homo sapiens
280408 Mus musculus
287531 Rattus norvegicus
Ausgewählte Anbieter für RILP Proteine (RILP)
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