RAN Guanine Nucleotide Release Factor Proteine (RANGRF)

RANGRF encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Zusätzlich bieten wir Ihnen RAN Guanine Nucleotide Release Factor Antikörper (12) und RAN Guanine Nucleotide Release Factor Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte RANGRF RANGRF 287419  
RANGRF 29098 Q9HD47
RANGRF 57785 Q9JIB0
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Top RAN Guanine Nucleotide Release Factor Proteine auf antikoerper-online.de

Showing 6 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$554.07
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,442.00
Details

RANGRF Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Weitere Proteine zu RAN Guanine Nucleotide Release Factor (RANGRF) Interaktionspartnern

Zebrafish RAN Guanine Nucleotide Release Factor (RANGRF) Interaktionspartner

  1. Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and heart rate.

Human RAN Guanine Nucleotide Release Factor (RANGRF) Interaktionspartner

  1. Compound mutation of CACNA2D1 (zeige CACNA2D1 Proteine) and RANGRF genes were found. To the best of our knowledge, this is the first comprehensive description of the concurrence of these two mutations and histiocytoid cardiomyopathy.

  2. Results suggest that dominant-negative mutations in MOG1 can impair the trafficking of Na(v)1.5 to the membrane, leading to I(Na) reduction and clinical manifestation of Brugada syndrome.

  3. Our screening of Nav1.5 (zeige SCN5A Proteine) cofactor MOG1 uncovered a novel nonsense variant that appeared to be present at a higher frequency among these patients with atrial fibrillation and Brugada syndrome than control subjects.

  4. in cardiomyocytes, MOG1 is mostly localized in the cell membrane and co-localized with Nav1.5 (zeige SCN5A Proteine), indicating that MOG1 is a critical regulator of sodium channel function in the heart

Mouse (Murine) RAN Guanine Nucleotide Release Factor (RANGRF) Interaktionspartner

  1. in cardiomyocytes, MOG1 is mostly localized in the cell membrane and co-localized with Nav1.5 (zeige SCN5A Proteine), indicating that MOG1 is a critical regulator of sodium channel function in the heart

RAN Guanine Nucleotide Release Factor (RANGRF) Protein Überblick

Protein Überblick

This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit RANGRF

  • RAN guanine nucleotide release factor (Rangrf)
  • RAN guanine nucleotide release factor L homeolog (rangrf.L)
  • RAN guanine nucleotide release factor (RANGRF)
  • RAN guanine nucleotide release factor (rangrf)
  • Mog1 family protein (DDB_G0285871)
  • 2400006H24Rik Protein
  • DDBDRAFT_0186722 Protein
  • DDBDRAFT_0237751 Protein
  • DDB_0186722 Protein
  • DDB_0237751 Protein
  • HSPC236 Protein
  • Mog1 Protein
  • Rangnrf Protein
  • RANGRF Protein
  • RGD1563195 Protein
  • zmynd19 Protein

Bezeichner auf Proteinebene für RANGRF

ran guanine nucleotide release factor , RAN guanine nucleotide release factor , zinc finger, MYND domain containing 19 , Ran GTPase binding protein , MOG1 homolog , ran-binding protein MOG1

GENE ID SPEZIES
287419 Rattus norvegicus
398168 Xenopus laevis
479494 Canis lupus familiaris
496602 Xenopus (Silurana) tropicalis
559102 Danio rerio
8625326 Dictyostelium discoideum AX4
100529008 Ictalurus punctatus
29098 Homo sapiens
57785 Mus musculus
512506 Bos taurus
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