RAB1A, Member RAS Oncogene Family Proteine (RAB1A)

RAB1A encodes a member of the Ras superfamily of GTPases. Zusätzlich bieten wir Ihnen RAB1A Antikörper (47) und RAB1A Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RAB1A 5861 P62820
RAB1A 19324 P62821
RAB1A 81754 Q6NYB7
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Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,498.83
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,498.83
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Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,498.83
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Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human RAB1A Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$412.19
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Escherichia coli (E. coli) Maus GST-His-Tag   50 μg Anmelden zum Anzeigen 6 bis 7 Tage
$306.13
Details

RAB1A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)
,
Rat (Rattus)

Weitere Proteine zu RAB1A, Member RAS Oncogene Family (RAB1A) Interaktionspartnern

Human RAB1A, Member RAS Oncogene Family (RAB1A) Interaktionspartner

  1. Rab1 is regulated by the host in a similar fashion, and that the innate immunity kinase TAK1 (zeige MAP3K7 Proteine) and Legionella effectors compete to regulate Rab1 by switch II modifications during infection.

  2. Rab1A may be involved in the pathogenesis of human lung cancer in an mTOR (zeige FRAP1 Proteine)- and MAPK (zeige MAPK1 Proteine)-independent manner.

  3. In clinical samples, the expression of Rab1A or DHX33 (zeige DHX33 Proteine) was reversely correlated with miR (zeige MLXIP Proteine)-634. Re-expression of Rab1A or DHX33 (zeige DHX33 Proteine) abrogated the miR (zeige MLXIP Proteine)-634-mediated inhibition of cell proliferation and migration. Collectively, our data suggest a tumor suppressor role of miR (zeige MLXIP Proteine)-634 in hepatocellular carcinoma.

  4. New Rab1 binding sites have been discovered using an ensemble of clustering methods.

  5. Leucine-rich repeat kinase 2 (LRRK2) can interact with several Rab proteins, and such ractions may serve to recruit LRRK2 to distinct subcellular organelles to phosphorylate select substrate proteins involved in membrane trafficking events.

  6. As a Rab1a effector, C9orf72 (zeige C9ORF72 Proteine) controls initiation of autophagy by regulating the Rab1a-dependent trafficking of the ULK1 (zeige ULK1 Proteine) autophagy initiation complex to the phagophore.

  7. our data indicate that miR (zeige MLXIP Proteine)-1202 suppresses proliferation and induces endoplasmic reticulum stress and apoptosis through targeting and inhibiting Rab1A in glioma cells. These results suggest miR (zeige MLXIP Proteine)-1202 as a potential therapeutic target for the treatment of glioma patients.

  8. Upregulation of RAB1A is associated with triple-negative breast cancer.

  9. For RAB1A, a high accuracy for the discrimination of human hepatocellular carcinoma and nontumorous liver tissue was observed.

  10. The ability of Rab1 to regulate WHAMM and the Arp2/3 complex represents a distinct strategy for membrane remodeling in which a Rab G-protein recruits the actin nucleation machinery but dampens its activity.

Zebrafish RAB1A, Member RAS Oncogene Family (RAB1A) Interaktionspartner

  1. The authors demonstrate in zebrafish that nf1 (zeige NF1 Proteine) loss leads to aberrant activation of RAS signaling in MYCN (zeige MYCN Proteine)-induced neuroblastomas that arise in these precursors, and that the GTPase-activating protein (GAP)-related domain (GRD) is sufficient to suppress the acceleration of neuroblastoma (zeige ARHGEF16 Proteine) in nf1 (zeige NF1 Proteine)-deficient fish, but not the hypertrophy of sympathoadrenal cells in nf1 (zeige NF1 Proteine) mutant embryos.

  2. Ras activity levels control the repopulation and expansion of adult melanocyte precursors after tissue loss, enabling the recovery of patterned melanocyte stripes during zebrafish appendage regeneration.

Pig (Porcine) RAB1A, Member RAS Oncogene Family (RAB1A) Interaktionspartner

Fruit Fly (Drosophila melanogaster) RAB1A, Member RAS Oncogene Family (RAB1A) Interaktionspartner

  1. It has been demonstrated that the COG (zeige TG Proteine) complex cooperates with Rab1 and GOLPH3 (zeige GOLPH3 Proteine) to regulate Golgi trafficking, and that overexpression of Rab1 can rescue the cytokinesis and locomotor defects associated with loss of Cog7 (zeige COG7 Proteine).

  2. Drosophila Tempura, a novel protein prenyltransferase alpha subunit, regulates notch signaling via Rab1 and Rab11.

  3. Results suggest a novel function for Rab1a in the regulation of cell migration through controlling integrin beta1 recycling and localization to lipid rafts via a specific downstream effector pathway.

Mouse (Murine) RAB1A, Member RAS Oncogene Family (RAB1A) Interaktionspartner

  1. clear effect of subcutaneous zoledronic acid administration in vivo on the prenylation of Rab1A, Rab5B (zeige RAB5B Proteine), Rab7A (zeige RAB7A Proteine) and Rab14 (zeige RAB14 Proteine) in mouse peritoneal macrophages, confirming that systemic treatment with bisphosphonate drug can inhibit prenylation in myeloid cells in vivo outside the skeleton.

  2. Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP

  3. These data indicate that AMPylation of Rab1 is an effective strategy to maintain this GTPase (zeige RACGAP1 Proteine) on the Legionella-containing vacuole membrane.

  4. Rab1A is the first crucial component of the anterograde melanosome transport machinery to be identified in mammalian skin melanocytes.

  5. Acute expression of Rab1 and Rab3d (zeige RAB3D Proteine) DN constructs partially alleviated this negative feedback mechanism and resulted in impaired ER to Golgi trafficking of procollagen.

  6. Legionella pneumophila SidD catalyzed AMP (zeige TMPRSS5 Proteine) release from Rab1, generating de-AMPylated Rab1 accessible for inactivation by LepB; identified SidD as missing link connecting processes of early Rab1 accumulation and subsequent removal during infection

  7. Results suggest a novel function for Rab1a in the regulation of cell migration through controlling integrin beta1 recycling and localization to lipid rafts via a specific downstream effector pathway.

  8. Rab1 and Rab6 GTPases may play a role in modulating the function of retina by mediating the transport of nascent proteins along the early secretary pathway, particularly in the process of the light adaptation.

  9. Data show Trs130 (zeige TRAPPC9 Proteine) (mTrs130) is a component of an analogous TRAPP complex that this complex is enriched on COPI (Coat Protein (zeige GOLPH3 Proteine) I (zeige ANXA2 Proteine))-coated vesicles it specifically activates Rab1.

  10. elevated expression of Rab1 protected against alpha-Synuclein-induced dopaminergic neuron loss in animal models of Parkinson Disease

RAB1A Protein Überblick

Protein Überblick

This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.

Genbezeichner und Symbole assoziert mit RAB1A

  • RAB1A, member RAS oncogene family (RAB1A)
  • RAB1A, member RAS oncogene family b (rab1ab)
  • RAB1A, member RAS oncogene family L homeolog (rab1a.L)
  • RAB1B, member RAS oncogene family (RAB1B)
  • RAB1A, member RAS oncogene family (rab1a)
  • CG3320 gene product from transcript CG3320-RA (Rab1)
  • rab1A protein (rab1A)
  • PfRab1a (Rab1a)
  • hypothetical protein (Rab1a)
  • Rab GTPase (rab1A)
  • angiogenin (ANG)
  • RAB1A, member RAS oncogene family (Rab1a)
  • AAF55873 Protein
  • Ac2-048 Protein
  • CG3320 Protein
  • dar6 Protein
  • DDBDRAFT_0185730 Protein
  • DDBDRAFT_0191476 Protein
  • DDB_0185730 Protein
  • DDB_0191476 Protein
  • Dmel\\CG3320 Protein
  • DmRab1 Protein
  • Dm Rab1 Protein
  • drab1 Protein
  • fb53a02 Protein
  • Gtbp Protein
  • MGC53138 Protein
  • mKIAA3012 Protein
  • oncogene Protein
  • Rab-1 Protein
  • Rab1 Protein
  • Rab1A Protein
  • RAB1B Protein
  • Rab1r Protein
  • RAS Protein
  • si:zc101n13.3 Protein
  • wu:fb53a02 Protein
  • Ypt1 Protein

Bezeichner auf Proteinebene für RAB1A

GTP binding protein Rab1a , RAB1, member RAS oncogene family , Rab GTPase YPT1 homolog , YPT1-related protein , ras-related protein Rab-1A , RAB1A, member RAS oncogene family , RAB1B, member RAS oncogene family , Rab-protein 1 , CG3320-PA , Rab1-PA , dendritic arbor reduction 6 , rab1A protein , PfRab1a , hypothetical protein , RNase 5 , angiogenin , ribonuclease 5 , ras-related YPT1 protein

GENE ID SPEZIES
5861 Homo sapiens
368883 Danio rerio
379830 Xenopus laevis
403774 Canis lupus familiaris
421273 Gallus gallus
448007 Xenopus (Silurana) tropicalis
459280 Pan troglodytes
539339 Bos taurus
595116 Sus scrofa
696962 Macaca mulatta
100196294 Salmo salar
100302065 Ovis aries
100339709 Oryctolagus cuniculus
42524 Drosophila melanogaster
553886 Lotus japonicus
812953 Plasmodium falciparum 3D7
7195044 Phaeodactylum tricornutum CCAP 1055/1
8624312 Dictyostelium discoideum AX4
100034041 Equus caballus
19324 Mus musculus
81754 Rattus norvegicus
101087312 Felis catus
100860796 Capra hircus
100719957 Cavia porcellus
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