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The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. Zusätzlich bieten wir Ihnen RAB17 Antikörper (82) und viele weitere Produktgruppen zu diesem Protein an.
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The selectivity in syntaxin binding and apical protein redistribution further suggests that rab17 and syntaxin 2 (zeige STX2 Proteine) mediate fusion of transcytotic vesicles at the apical surface.
Rabex-5 (zeige RABGEF1 Proteine) regulates neurite morphogenesis of hippocampal neurons by activating at least two downstream targets, Rab5 (zeige RAB5A Proteine), which is localized in both axons and dendrites, and Rab17, which is localized in dendrites alone
Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons.
Data reveal new functions for recycling endosomes and Rab17 in pigmentation through a distal step in the process of melanosome release via filopodia.
Mass spectrometry and immunofluorescence microscopy of efferosomes and phagosomes in macrophages demonstrated that efferosomes lacked the proteins required for antigen presentation and instead recruited the recycling regulator Rab17.
Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk MAPK (zeige MAPK1 Proteine) signaling.
Rab17 might act as a tumour suppressor gene in hepatocellular carcinoma , and the anti-tumour effects of Rab17 might be partially mediated by the Erk (zeige EPHB2 Proteine) pathway.
These results suggest that Rab17 and Rab17-mediated REs are involved in Streptococcus pyogenes-containing autophagosome-like vacuole formation.
Knockdown of either Rab17 or liprin (zeige PPFIA1 Proteine)-beta2 restores invasiveness of ERK2 (zeige MAPK1 Proteine)-depleted cells, indicating that ERK2 (zeige MAPK1 Proteine) drives invasion of MDA-MB-231 cells by suppressing expression of these genes.
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993
, RAB17, member RAS oncogene family
, ras-related protein Rab-17