anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Antikörper

PDHA1 encodes a subunit of mitochondrial ATP synthase. Zusätzlich bieten wir Ihnen PDHA1 Kits (16) und PDHA1 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDHA1 5160 P08559
PDHA1 18597 P35486
PDHA1 29554  
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Top anti-PDHA1 Antikörper auf antikoerper-online.de

Showing 10 out of 150 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, IP, WB Western Blot: Pyruvate Dehydrogenase E1-alpha subunit [p Ser293] Antibody [ABIN4099989] - Detection of PDHE1 alpha [S293] in an in vitro autophosphorylation of PDH complex in response to different stimulants: (-) none, H202-hydrogen peroxide, AR-anhydroretinol, Rol-retinol, RA-retinoic acid, PMA, Lipid-PKC lipid activator. -Photo courtesy of Dr. Beatrice Hoyos, Memorial Sloan-Kettering Cancer Center. Immunocytochemistry/Immunofluorescence: Pyruvate Dehydrogenase E1-alpha subunit [p Ser293] Antibody [ABIN4099989] - Pyruvate Dehydrogenase E1-alpha subunit [p Ser293] antibody (1:250) was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PDHA1 Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IP, IHC, WB Immunohistochemical analysis of PDHA1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of PDHA1 expression in HepG2 (A), HUVEC (B), HeLa (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PDHA1 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate <b>Sample type</b>:Huh7 HepG2 (50ug)<br><b>Primary Antibody Dilution:</b> 1:500<br><b>Image Submitted by:</b> Partha Kasturi<br>University of Kansas Medical Center 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Maus Unkonjugiert FACS, IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
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Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PDHA1 Antibody (Center) in Hela cell line lysates (35ug/lane). PDHA1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of mouse heart and mouse skeletal muscle cell lines, using PDHA1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of PDHA1 Antibody (Center) (ABIN653604) in Hela cell line lysates (35 µg/lane). PDHA1 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert WB PDHA1 Antibody (ABIN653605) western blot analysis in HepG2 cell line lysates (35 µg/lane).This demonstrates the PDHA1 antibody detected the PDHA1 protein (arrow). Western blot analysis of PDHA1 (arrow) using rabbit polyclonal PDHA1 Antibody (ABIN653605). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PDHA1 gene. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

PDHA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PDHA1 Antikörper

  1. Human Polyclonal PDHA1 Primary Antibody für ICC, IF - ABIN409998 : Acin-Perez, Hoyos, Zhao, Vinogradov, Fischman, Harris, Leitges, Wongsiriroj, Blaner, Manfredi, Hammerling: Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)
    Show all 24 Pubmed References

  2. Polyclonal PDHA1 Primary Antibody für WB - ABIN540348 : McFate, Mohyeldin, Lu, Thakar, Henriques, Halim, Wu, Schell, Tsang, Teahan, Zhou, Califano, Jeoung, Harris, Verma: Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. in The Journal of biological chemistry 2008 (PubMed)

Weitere Antikörper gegen PDHA1 Interaktionspartner

Human Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Interaktionspartner

  1. Case demonstrates fetal akinesia deformation sequence due to a de novo hemizygous c.498C > T splice-site mutation in the pyruvate dehydrogenase-alpha 1 (PDHA1) gene.

  2. Data show that metformin reduces hypoxia-inducible factor 1alpha (HIF-1alpha (zeige HIF1A Antikörper)) gene expression and increases pyruvate dehydrogenase (PDH (zeige PDP Antikörper)) expression.

  3. The report PDHA1 as a new component of brainstem-type Lewy bodies in idiopathic PD, DLB and PARK14, the level of PDHA1 protein being significantly decreased in the putamen and substantia nigra of patients with idiopathic Parkinson's disease .

  4. Findings show that serine-threonine-tyrosine kinase 1 (NOK (zeige STYK1 Antikörper)) mediates glycolysis and nuclear pyruvate dehydrogenase (zeige PDP Antikörper) complex (PDC (zeige PNKD Antikörper)) associated histone acetylation.

  5. The association of mitochondrial microphthalmia-associated transcription factor (MITF (zeige MITF Antikörper)) with pyruvate dehydrogenase (PDH (zeige PDP Antikörper)) emerges as an important regulator of mast cell function. Our findings indicate that PDH (zeige PDP Antikörper) could arise as a new target for the manipulation of allergic diseases.

  6. our results show that negative PDHA1 gene expressionis associated with significantly higher cell stemness in prostate cancer cells and reduced protein expression of this gene is associated with shorter clinical outcome in prostate cancers.

  7. ATP5G1 (zeige ATP5G1 Antikörper) turnover increases upon depletion of ZC3H14 (zeige ZC3H14 Antikörper), double knockdown of ZC3H14 (zeige ZC3H14 Antikörper) and the nonsense-mediated decay factor, UPF1 (zeige UPF1 Antikörper), rescues ATP5G1 (zeige ATP5G1 Antikörper) transcript levels. Furthermore, fractionation reveals an increase in the amount of ATP5G1 (zeige ATP5G1 Antikörper) pre-mRNA that reaches the cytoplasm when ZC3H14 (zeige ZC3H14 Antikörper) is depleted and that ZC3H14 (zeige ZC3H14 Antikörper) binds to ATP5G1 (zeige ATP5G1 Antikörper) pre-mRNA in the nucleus.

  8. oncoprotein HBXIP (zeige HBXIP Antikörper) enhances glucose metabolism reprogramming through suppressing SCO2 (zeige SCO2 Antikörper) and PDHA1 in breast cancer

  9. MPO (zeige MPO Antikörper) and BPI (zeige BPI Antikörper) in CD4 (zeige CD4 Antikörper)(+)T-lymphocytes, and PDHA1 and MRPL42 (zeige MRPL42 Antikörper) in CD8 (zeige CD8A Antikörper)(+) T-lymphocytes might be used as specific biomarkers of severe asthma progression.

  10. Phosphorylation at distinct serine and tyrosine residues inhibits PDHA1 through distinct mechanisms to impact active site accessibility.

Mouse (Murine) Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Interaktionspartner

  1. Cardiac PDH (zeige PDP Antikörper) E1alpha deficiency impairs ischemic AMP-activated protein kinase (zeige PRKAA2 Antikörper) signaling and sensitizes hearts to the toxicological actions of ischemic stress.

  2. Taken together, our results indicate that the redox sensing and ROS (zeige ROS1 Antikörper) forming properties of Pdh (zeige PDP Antikörper) and Ogdh (zeige alphaKGDHC Antikörper) are linked to S-glutathionylation

  3. Systemic Pyruvate Dehydrogenase (zeige PDP Antikörper) Deficiency is associated with Cerebral Developmental Abnormalities.

  4. The association of mitochondrial microphthalmia-associated transcription factor (MITF (zeige MITF Antikörper)) with pyruvate dehydrogenase (PDH (zeige PDP Antikörper)) emerges as an important regulator of mast cell function. Our findings indicate that PDH (zeige PDP Antikörper) could arise as a new target for the manipulation of allergic diseases.

  5. skeletal muscle IL-6 (zeige IL6 Antikörper) contributes to the regulation of PDH (zeige PDP Antikörper) at rest and during prolonged exercise.

  6. The present findings suggest that IL-6 (zeige IL6 Antikörper) contributes to regulating the PDHa activity and hence carbohydrate oxidation, but the metabolic state of the muscle seems to determine the outcome of this regulation

  7. Liver-specific pyruvate dehydrogenase (zeige PDP Antikörper) complex deficiency upregulates lipogenesis in adipose tissue and improves peripheral insulin (zeige INS Antikörper) sensitivity.

  8. PGC-1alpha regulates PDH (zeige PDP Antikörper)-E1alpha protein content in parallel with mitochondrial oxidative proteins, but does not seem to influence PDH (zeige PDP Antikörper) regulation in mouse skeletal muscle in response to fasting and in recovery from exercise.

  9. Embryos carrying predominantly the Pdha1(deletion in exon 8, Deltaex8) allele were found to be globally delayed in development by 9.5 days postcoitus, with resorption occurring over the following several days.

Zebrafish Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Interaktionspartner

  1. The study provired that pyruvate dehydrogenase (zeige PDK2 Antikörper)-deficient mutant caused the retinal drficits in zebrafish.

PDHA1 Antigen-Profil

Protein Überblick

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified.

Genbezeichner und Symbole assoziert mit PDHA1

  • pyruvate dehydrogenase E1 alpha 1 subunit (PDHA1) Antikörper
  • pyruvate dehydrogenase E1 alpha 1 (Pdha1) Antikörper
  • pyruvate dehydrogenase E1 alpha 1 subunit (Pdha1) Antikörper
  • pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1) Antikörper
  • pyruvate dehydrogenase E1 alpha 1 subunit (pdha1) Antikörper
  • pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene (LOC719277) Antikörper
  • 2-oxo acid dehydrogenase (VNG_RS07485) Antikörper
  • pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha (RR_RS04695) Antikörper
  • pyruvate dehydrogenase alpha subunit protein (pdhA1) Antikörper
  • pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit (pdhA1) Antikörper
  • precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit (PDHA1) Antikörper
  • pyruvate dehydrogenase (PDHA1) Antikörper
  • pyruvate dehydrogenase E1 alpha 1 subunit b (pdha1b) Antikörper
  • pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog (pdha1.S) Antikörper
  • pdha Antikörper
  • Pdha-1 Antikörper
  • Pdha1 Antikörper
  • pdha1-a Antikörper
  • pdha1-b Antikörper
  • pdhce1a Antikörper
  • phe1a Antikörper
  • wu:fp73b04 Antikörper
  • zgc:92705 Antikörper

Bezeichner auf Proteinebene für PDHA1

PDHE1-A type I , pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial , pyruvate dehydrogenase complex, E1-alpha polypeptide 1 , pyruvate dehydrogenase E1alpha subunit , pyruvate dehydrogenase E1 alpha 1 , pyruvate dehydrogenase E1 component alpha subunit , pyruvate dehydrogenase alpha 1 , pyruvate dehydrogenase (lipoamide) alpha 1 , PdhA1 , pyruvate dehydrogenase alpha subunit , pyruvate dehydrogenase E1 component subunit alpha , pyruvate dehydrogenase alpha subunit protein , pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit , precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit , pyruvate dehydrogenase , Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial , pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like , fp73b04 , pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog

GENE ID SPEZIES
5160 Homo sapiens
18597 Mus musculus
29554 Rattus norvegicus
407109 Bos taurus
418610 Gallus gallus
465525 Pan troglodytes
480858 Canis lupus familiaris
549826 Xenopus (Silurana) tropicalis
719277 Macaca mulatta
1448416 Halobacterium sp. NRC-1
3129238 Haloarcula marismortui ATCC 43049
3893971 Rhizobium etli CFN 42
6400117 Rhizobium etli CIAT 652
7195506 Phaeodactylum tricornutum CCAP 1055/1
7369176 Agrobacterium radiobacter K84
7450426 Thalassiosira pseudonana CCMP1335
100174745 Pongo abelii
100294678 Sus scrofa
100357349 Oryctolagus cuniculus
100400144 Callithrix jacchus
100471829 Ailuropoda melanoleuca
100587584 Nomascus leucogenys
436672 Danio rerio
100735725 Cavia porcellus
447434 Xenopus laevis
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