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PCDH17 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. Zusätzlich bieten wir Ihnen PCDH17 Proteine (4) und PCDH17 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 62 products:
Cow (Bovine) Polyclonal PCDH17 Primary Antibody für WB - ABIN2785751
Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. in Genome biology 2008
Mouse (Murine) Polyclonal PCDH17 Primary Antibody für ELISA, WB - ABIN4347946
Giefing, Zemke, Brauze, Kostrzewska-Poczekaj, Luczak, Szaumkessel, Pelinska, Kiwerska, Tönnies, Grenman, Figlerowicz, Siebert, Szyfter, Jarmuz: High resolution ArrayCGH and expression profiling identifies PTPRD and PCDH17/PCH68 as tumor suppressor gene candidates in laryngeal squamous cell carcinoma. in Genes, chromosomes & cancer 2011
Methylation of PCDH17 could play an important role in development and progression of high-grade serous ovarian carcinoma (HGSOC)and has potential to become a target in the search for new clinical biomarkers
PCDH17 methylation in serum is a potential prognostic biomarker for patients with renal cell carcinoma (zeige MOK Antikörper) after surgery.
PCDH17 functions as a tumor suppressor inhibiting Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling and metastasis in breast cancer but is frequently methylated in primary tumors which could be a potential biomarker.
Aberrant methylation of protocadherin 17 is associated with acute lymphoblastic leukemia.
PCDH-17 inhibited metastasis via EGFR (zeige EGFR Antikörper)/MEK (zeige MAP2K1 Antikörper)/ERK (zeige EPHB2 Antikörper) signaling pathway.
DNA methylation (zeige HELLS Antikörper) in a combination of POU4F2 (zeige POU4F2 Antikörper)/PCDH17 has yielded the highest sensitivity and specificity of 90.00% and 93.96% in all the 312 individuals, showing the capability of detecting bladder cancer effectively among pathologically varied sample groups.
PCDH17 methylation in serum is a frequent event in early-stage prostate cancer, and it is an independent predictor of BCR (zeige BCR Antikörper) after radical prostatectomy
PCDH17 methylation occurred more frequently and was associated with malignant clinicopathological characteristics and poor prognosis in clear cell renal cell carcinoma (zeige MOK Antikörper) patients
PCDH17 promoter methylation is closely associated with bladder cancer malignancy and may be used as an independent predictor of clinical outcomes in patients with bladder cancer.
PCDH17 promoter methylation was significantly associated with malignant behaviour and poor prognosis of bladder cancer
Pcdh17 recruits the WAVE complex, Lamellipodin (zeige RAPH1 Antikörper), and Ena/VASP (zeige VASP Antikörper) to cell-cell contacts, converting these sites into motile structures.
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain.