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human homolog plays a role in anti-apoptosis.
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Prothymosin-alpha variants elicit anti-HIV-1 response via TLR4 (zeige TLR4 Antikörper) dependent and independent pathways.
PTMA is a potential novel therapeutic target for type 2 diabetes
disease-free survival and overall survival rates were significantly lower among colorectal cancer patients with PTMA- and TP53 (zeige TP53 Antikörper)-positive tumors
Data suggest that KEAP1 (kelch-like ECH-associated protein 1 (zeige KEAP1 Antikörper)) mutations (as those observed in lung cancer patients) affect conformation/folding/stability of KEAP1 (zeige KEAP1 Antikörper) and binding affinity for ligands PTMA and NRF2 (nuclear factor erythroid 2-like 2 (zeige NFE2L2 Antikörper)).
Data suggest that plasma thymosin-alpha1 (TA1 (zeige TAAR1 Antikörper)) and prothymosin-alpha (PTMA) level may be a biomarker for differentiating between renal cell carcinoma (zeige MOK Antikörper) (RCC (zeige XRCC1 Antikörper)) and urothelial carcinoma.
prothymosin-alpha expression is a determinant of disease progression in superficial bladder cancer
PTalpha (zeige PTCRA Antikörper) offers cardioprotection against ischemic injury by an Akt (zeige AKT1 Antikörper)-dependent mechanism.
These results demonstrate the clinical relevance of prothymosin alpha in regulating acetylation events during the pathogenesis of emphysema.
The PTMA is one of miR-1 target genes which involve in miR-1 inducing apoptosis.
Findings suggest that the binding of prothymosin alpha (ProTalpha) and Neh2 (zeige NEIL2 Antikörper) to Keap1 (zeige KEAP1 Antikörper) occurs synergistically via preformed structural elements.
Prothymosin alpha-knockout mice showed an impaired long-term potentiation induction in the hippocampus along with decreased neurogenesis.
Only neurons possess the specific mechanisms required to release prothymosin-alpha following cerebral ischemic stress in vivo.
Regional distribution and cell type-specific subcellular localization of Prothymosin alpha in brain.
Thymosin alpha-1 could relieve radiation-induced acute and late pulmonary injuries.
observations suggest that Talpha1 can positively modulate the haematopoietic functions of normal murine bone marrow cells, in addition to its myelorestorative role in tumour-bearing mice showing suppressed myelopoiesis [thymosin alpha-1]
thymosin alpha 1, a naturally occurring thymic peptide, induces functional maturation and interleukin-12 production by fungus-pulsed DCs through the p38 mitogen-activated protein kinase (zeige MAPK14 Antikörper)/nuclear factor (NF)-kappaB (zeige NFKB1 Antikörper)-dependent pathway.
ProT (zeige SLC6A7 Antikörper) overexpression in the kidneys of homozygous transgenic mice induced a PKD (zeige PRKD1 Antikörper) phenotype, which included polycystic kidneys, elevated blood urea nitrogen (BUN), and lethality at about 10 days of age.
Keap1 (zeige KEAP1 Antikörper)-bound prothymosin alpha peptide possesses a hairpin conformation and binds to cytoplasmic repressor Keap1 (zeige KEAP1 Antikörper) at the bottom region of the beta-propeller domain; complex formation occurs as a consequence of their complementary electrostatic interactions.
human homolog plays a role in anti-apoptosis
gene sequence 28
, prothymosin alpha
, prothymosin alpha protein
, prothymosin, alpha
, prothymosin, alpha (gene sequence 28)
, prothymosin alpha-B
, thymosin alpha1