Proteinase 3 Proteine (PRTN3)

Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.. Zusätzlich bieten wir Ihnen Proteinase 3 Antikörper (173) und Proteinase 3 Kits (54) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PRTN3 5657 P24158
PRTN3 314615  
PRTN3 19152 Q61096
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Top Proteinase 3 Proteine auf antikoerper-online.de

Showing 10 out of 27 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$720.00
Details
Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$385.00
Details
Escherichia coli (E. coli) Human GST tag Proteinase 3 (PRTN3) (AA 28-248), (full length) protein (GST tag) 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$242.00
Details
HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
$504.90
Details
Escherichia coli (E. coli) Human GST tag 50 μg Anmelden zum Anzeigen 11 Days
$341.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
Details
Human Cells Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$225.00
Details

PRTN3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, ,
Rat (Rattus)

Mouse (Murine) ,

Weitere Proteine zu Proteinase 3 (PRTN3) Interaktionspartnern

Human Proteinase 3 (PRTN3) Interaktionspartner

  1. Characterization of the CD177 (zeige CD177 Proteine) interaction with the ANCA antigen proteinase 3 responsible for autoimmune diseases has been reported.

  2. Our results demonstrate that in the early stage of sepsis, JMJD3 contributes to high levels of neutrophil mPR3 expression and thereby to the production of the inflammatory cytokine IL-1beta (zeige IL1B Proteine)

  3. A few peptides bound to proteinase 3 (PR3) hydrophobic pockets and inhibited PR3 binding to lipids, while the (KFF)3K d-peptide inshowed a significant affinity for the lipids.

  4. Studies indicate that the premature activation of proteinase 3 (PR3) would seriously harm the cell by its protease activity.

  5. this study shows that transgenic mice expressing human Proteinase 3 exhibit sustained neutrophil-associated peritonitis

  6. unique structural and functional characteristics of PR3 might be key contributors to the systemic inflammation and to the immune dysregulation observed in granulomatosis with polyangiitis.

  7. Our findings demonstrate how RAGE-PR3 interactions between human prostate cancer cells and the bone marrow microenvironment mediate bone metastasis during prostate cancer progression

  8. PRTN3 variants are associated with ANCA-associated vasculitis risk.

  9. Clinical manifestations varied ANCA-associated vasculitis categories, and neither MPO-ANCA nor PR3-ANCA significantly affected relapse of AAV.

  10. Changes in the DNA methylation (zeige HELLS Proteine) status of the PRTN3 promoter may predict the likelihood of stable remission and explain autoantigen gene regulation

Mouse (Murine) Proteinase 3 (PRTN3) Interaktionspartner

  1. Results provide evidence that proteinase 3 as a new factor involved in non-alcoholic fatty liver disease and insulin (zeige INS Proteine) resistance.

  2. In different murine models of apoptotic cell injection, the PR3-induced microenvironment instructed pDC-driven Th9/Th2 cell generation.

  3. PR3-ANCA is a promising biomarker in primary sclerosing cholangitis.

  4. Proteinase 3-mediated caspase-3 (zeige CASP3 Proteine) activation controls neutrophil spontaneous death

  5. Increased PRTN3 activity was associated with development of autoimmune diabetes mellitus in NOD mice.

  6. Phagocytosis of apoptotic PR3-expressing cells potentiates proinflammatory cytokines in vivo by resident murine peritoneal macrophages.

  7. the dual functions (activation/termination) of PR3 in IL-33 (zeige IL33 Proteine) biological activity.

  8. pathogenic effect of proteinase 3-specific antineutrophil cytoplasmic autoantibodies at local sites of inflammation.

  9. Murine and human proteinase 3 complexes have different interaction patterns with peptidic substrates.

  10. PR3 and neutrophil elastase (zeige ELANE Proteine) enhance neutrophil-dependent inflammation by eliminating the local antiinflammatory activity of progranulin (zeige GRN Proteine). Our results support the use of serine protease (zeige F2 Proteine) inhibitors as antiinflammatory agents.

Proteinase 3 (PRTN3) Protein Überblick

Protein Überblick

Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

Genbezeichner und Symbole assoziert mit Proteinase 3 Proteine (PRTN3)

  • proteinase 3 L homeolog (prtn3.L)
  • proteinase 3 (PRTN3)
  • proteinase 3 (Prtn3)
  • ACPA Protein
  • AGP7 Protein
  • C-ANCA Protein
  • CANCA Protein
  • ela2 Protein
  • MBN Protein
  • MBT Protein
  • MGC132250 Protein
  • mPR3 Protein
  • NP-4 Protein
  • NP4 Protein
  • P29 Protein
  • PR-3 Protein
  • PR3 Protein

Bezeichner auf Proteinebene für Proteinase 3 Proteine (PRTN3)

proteinase 3 , C-ANCA antigen , Wegener granulomatosis autoantigen , azurophil granule protein 7 , leukocyte proteinase 3 , myeloblastin , neutrophil proteinase 4 , serine proteinase, neutrophil , wegener autoantigen , PR-3

GENE ID SPEZIES
496090 Xenopus laevis
5657 Homo sapiens
314615 Rattus norvegicus
19152 Mus musculus
100298591 Bos taurus
Ausgewählte Anbieter für Proteinase 3 Proteine (PRTN3)
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