anti-Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) Antikörper

The protein encoded by PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen PTPN13 Proteine (10) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTPN13 5783 Q12923
PTPN13 19249 Q64512
PTPN13 498331  
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Top anti-PTPN13 Antikörper auf antikoerper-online.de

Showing 10 out of 73 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from LOVO cells, using FAP-1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FAP-1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p) Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PTPN13 antibody ABIN214667 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PTPN13 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (fro), IHC (p), IP, WB 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC (p), WB Western blot analysis of FAP 1 expression in LOVO cell extract ABIN6268891 staining LOVO cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6266990 staining LOVO by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis on LOVO cell lysate using FAP-1 Antibody,The lane on the left is treated with the antigen-specific peptide. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Immunohistochemistry-Paraffin: PTPN13/PTPL1 Antibody [ABIN43485939] - Formalin-fixed, paraffin embedded ovarian carcinoma cores from a tissue microarray at 1:2000. A-D, samples are from four different patients. A1-D1 are high magnification images from A-D, respectively. Hematoxylin-eosin counterstain. Immunohistochemistry-Paraffin: PTPN13/PTPL1 Antibody [ABIN43485939] - Analysis of PTPN13/PTPL1 in cell lines using this antibody at 1:2000. In ovarian carcinoma cell lines PTPN13/PTPL1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human 293 kidney and Jurkat T cell lines were used as positive and negative controls, respectively. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$418.10
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-PTPN13 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1804004 concentration 10 µg/mL. Anti-PTPN13 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1804004 concentration 10 µg/mL. 250 μL Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: PTPN13/PTPL1 Antibody [NBP1-02579] - Staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg Anmelden zum Anzeigen 10 bis 13 Tage
$559.35
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$434.50
Details
Human Kaninchen Unkonjugiert IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PTPN13at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Kidney (formalin-fixed, paraffin-embedded) stained with PTPN13at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 0.25 mL Anmelden zum Anzeigen 11 bis 13 Tage
$768.40
Details

Am meisten referenzierte anti-PTPN13 Antikörper

  1. Human Polyclonal PTPN13 Primary Antibody für ICC, IF - ABIN4348593 : Meinhold-Heerlein, Stenner-Liewen, Liewen, Kitada, Krajewska, Krajewski, Zapata, Monks, Scudiero, Bauknecht, Reed: Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer. in The American journal of pathology 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PTPN13 Primary Antibody für IF (p), IHC (p) - ABIN714341 : Evrard, Lecce, Michelis, Nomura-Kitabayashi, Pandey, Purushothaman, dEscamard, Li, Hadri, Fujitani, Moreno, Benard, Rimmele, Cohain, Mecham, Randolph, Nabel, Hajjar, Fuster, Boehm, Kovacic: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability. in Nature communications 2016 (PubMed)

Weitere Antikörper gegen PTPN13 Interaktionspartner

Human Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) Interaktionspartner

  1. MicroRNA-30e-5p promotes cell growth by targeting PTPN13 and indicates poor survival and recurrence in lung adenocarcinoma.

  2. The single nucleotide polymorphism genotype of PTPN13 exon 39 was determined in DNA extracted from blood samples from 174 sporadic colorectal cancer patients and 176 healthy individuals. The risk of colorectal cancer was 2.087 times greater for patients with the GG genotype than for those with the TT genotype. PTPN13 rs989902 is significantly associated with the risk of colorectal cancer in the Polish population.

  3. suggest that CAFs, irrespective of identity, have low influence on the degree of tumor infiltration by inflammatory- and/or immune-cells. However, CAFFAP may exert immuno-adjuvant roles in NSCLC, and targeting CAFs should be cautiously considered

  4. we found that miR-26a confers epidermal growth factor receptor-targeted tyrosine kinase inhibitors resistance of non-small cell lung cancer cells by targeting and silencing PTPN13

  5. Fap1 inhibition increased Fas sensitivity and decreased beta-catenin activity in human CD34+ CML cells

  6. the crystal structure of the PTP-Bas PDZ1 domain at 1.6 A resolution, is reported.

  7. PTPN13 overexpression significantly inhibited the progression of HCC cells.

  8. Mutation in PTPN13 gene is associated with gastric cancer peritoneal carcinomatosis.

  9. This work studied heat diffusion in the well-known PDZ-2 protein, and confirmed that this protein has two cognate allosteric pathways and that heat flows preferentially through these.

  10. Necl-4 serves as a novel regulator for contact inhibition of cell movement and proliferation cooperatively with the VEGF receptor and PTPN13

  11. A PDZ-mediated interaction of PTPN13 and PTEN is described with possible relevance for tumor suppression.

  12. The effect of the viscogens sucrose, and glycerol on the kinetic response of a photoperturbed PTPN13 is investigated.

  13. A comprehensive molecular dynamics simulation study of the PDZ2 domain of human tyrosine phosphatase 1E in the ligand-bound and -free state, as well as the photoswitchable protein in the cis and trans states of the photoswitch

  14. Thus, our results suggest a previously unknown Stat3-PTPN13 molecular network controlling squamous cell lung carcinoma development

  15. Association of rs7014346 in POU5F1P1, rs989902 in PTPN13, and rs7003146 in TCF7L2 with variations in the risk of breast cancer in a Chinese Han population.

  16. HCV induced increased expression of miR200c can down modulate the expression of FAP1, a critical regulator of Src and MAP kinase pathway that play an important role in the production of fibrogenic growth factors and development of fibrosis.

  17. selective autophagic degradation of the phosphatase Fap-1 promotes Fas apoptosis.

  18. Low PTPN13 expression is associated with invasion and metastasis of lung squamous cell carcinoma.

  19. The loss of PTPL1 and PKC-delta expression in poorly differentiated, more aggressive human prostate cancers indicate that their absence could be related to apoptosis resistance and tumor progression.

  20. Fap1-dependent inactivation of Gsk3beta and consequent stabilization of betacatenin in these cells. Consistent with this, Bcr-abl(+) cells exhibited a Fap1-dependent increase in betacatenin activity.

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) Interaktionspartner

  1. contributions of Fap1 to tyrosine kinase inhibitors (TKI)resistance, CML blast crisis, and relapse after TKI discontinuation

  2. The data show that the levels of PTPN13 and beta-catenin must be strictly regulated by extracellular signaling to regulate hematopoietic stem cells attachment to the bone marrow niche and the balance between proliferation and quiescence.

  3. The study presents a detailed kinetics analysis of the interaction between PTP-BL PDZ2 domain and a peptide mimicking the PDZ binding motif of APC.

  4. SDCCAG3 forms a complex with PTPN13. Interaction of SDCCAG3 with PTPN13 is mediated via the FERM domain of PTPN13 and via the N-terminus of SDCCAG3.

  5. Data indicate that Bcr-abl increases PTPN13 promoter activity in an Icsbp-dependent manner.

  6. Since PTPL1 catalytic activity is important for cell transformation, VCP regulation by PTPL1 might be important for tumorigenesis.

  7. These findings demonstrate a key role for PTP-BL in 3T3-L1 and mouse embryo fibroblasts-derived adipocyte differentiation that is independent of its enzymatic activity.

  8. Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL

  9. With delayed kinetics, ephrinB ligands recruit the cytoplasmic PDZ domain containing protein tyrosine phosphatase PTP-BL and are dephosphorylated.

  10. FAP-1 has a role in binding to, and consequently inhibition of, Fas export to the cell surface

  11. examination of potential role of PTP-BL in the dynamics of the cortical actin cytoskeleton

  12. In alternatively spliced variant structural changes have imp[lications in the functional role of PTP-BL

  13. a very mild but significant impairment of motor nerve repair was observed in PTP-BL mutant mice

  14. Involved in the regulation of the meiotic cell cycle.

  15. PTP-BL facilitates both retinal ganglion cell neurite initiation and survival of activated retinal glia

  16. Different pools of PTP-BL-containing protein complexes can be discerned in neuronal cells, reflecting distinct molecular microenvironments in which PTP-BL may exert its function.

  17. The interferon consensus sequence-binding protein (ICSBP/IRF8) represses PTPN13 gene transcription in differentiating myeloid cells

PTPN13 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Genbezeichner und Symbole assoziert mit PTPN13

  • protein tyrosine phosphatase, non-receptor type 13 (PTPN13) Antikörper
  • tyrosine-protein phosphatase non-receptor type 13 (LOC100540743) Antikörper
  • protein tyrosine phosphatase, non-receptor type 13 (ptpn13) Antikörper
  • protein tyrosine phosphatase, non-receptor type 13 (Ptpn13) Antikörper
  • AI324989 Antikörper
  • FAP-1 Antikörper
  • hPTP1E Antikörper
  • PNP1 Antikörper
  • ptp Antikörper
  • PTP-BAS Antikörper
  • Ptp-bl Antikörper
  • PTP1E Antikörper
  • PTPL1 Antikörper
  • PTPLE Antikörper
  • PTPN13 Antikörper
  • Ptpri Antikörper
  • RIP Antikörper
  • wu:fb50g04 Antikörper
  • zgc:162319 Antikörper

Bezeichner auf Proteinebene für PTPN13

fas-associated protein-tyrosine phosphatase 1 , hPTPE1 , protein-tyrosine phosphatase 1E , protein-tyrosine phosphatase PTPL1 , tyrosine-protein phosphatase non-receptor type 13 , protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) , protein tyrosine phosphatase, non-receptor type 13 , tyrosine-protein phosphatase non-receptor type 13-like , PTP36 , protein tyrosine phosphatase DPZPTP , protein tyrosine phosphatase PTP-BL , protein-tyrosine phosphatase RIP , tyrosine phosphatase , protein Tyr phosphatase , protein-tyrosine phosphatase BAS

GENE ID SPEZIES
5783 Homo sapiens
422591 Gallus gallus
461359 Pan troglodytes
100144609 Felis catus
100455138 Pongo abelii
100477379 Ailuropoda melanoleuca
100521910 Sus scrofa
100540743 Meleagris gallopavo
100566747 Anolis carolinensis
100603082 Nomascus leucogenys
19249 Mus musculus
498331 Rattus norvegicus
560883 Danio rerio
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