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The protein encoded by PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. Zusätzlich bieten wir Ihnen PTP4A1 Proteine (9) und PTP4A1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal PTP4A1 Primary Antibody für ELISA, WB - ABIN185274
Peng, Genin, Spinner, Diamond, Taub: The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer. in The Journal of biological chemistry 1998
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data shed new light on the structural basis underlying the interaction between PRL (zeige PRL Antikörper) phosphatases and CNNM transporters and provides a hypothesis about the molecular mechanism by which PRL-1, upon binding to CNNM2 (zeige CNNM2 Antikörper), might increase the intracellular concentration of Mg(2 (zeige MCOLN1 Antikörper)+) thereby contributing to tumor progression and metastasis.
Prl-1 is required for proper timing of liver regeneration after partial hepatectomy
PRL-1 binding to p115 (zeige ARHGAP4 Antikörper) RhoGAP (zeige ARHGAP1 Antikörper) provides a coordinated mechanism underlying ERK1/2 and RhoA (zeige RHOA Antikörper) activation
In cones and cone-derived cultured cells both Prl-1 activity and Prl-1 gene expression are modulated under oxidative stress.
PTP4A1 was overexpressed in ICC and played an important role in the progression and metastasis of ICC. The functional role of PTP4A1 was assumed to be acted by activation PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) signaling and promoting the EMT (zeige ITK Antikörper) process through two pivotal transcriptional factors Zeb1 (zeige ZEB1 Antikörper) and Snail (zeige SNAI1 Antikörper).
Results showed that SIAH1 (zeige SIAH1 Antikörper) and PTP4A1 expression was regulated by mir (zeige MLXIP Antikörper)-944 in breast cancer cells. miR (zeige MLXIP Antikörper)-944 binds directly the 3 UTR (zeige UTS2R Antikörper) of their promotor region.
miR (zeige MLXIP Antikörper)-601 inhibits growth and invasion of breast cancer cells by targeting PTP4A1.
Data indicate that protein-tyrosine-phosphatase of regenerating liver 1 (PRL1) gene was expressed much more highly in prostate cancer (PCa (zeige FLVCR1 Antikörper)) than in nonneoplastic prostate samples.
Upregulation of PRL-1 (zeige PLRG1 Antikörper) expression is inversely correlated with miR (zeige MLXIP Antikörper)-26a in primary cervical cancer tissues.
Data highlight the oncogenic function of PRL-1 (zeige PLRG1 Antikörper) in HCC (zeige FAM126A Antikörper) invasion and metastasis.
We confirmed with our previous findings that PTP4A1-PHF3-EYS (zeige EYS Antikörper) variants were significantly associated with alcohol dependence.
PTP4A1-PHF3-EYS (zeige EYS Antikörper) variants were associated with alcohol dependence.
Results suggest that TRP32 (zeige TXNL1 Antikörper) maintains the reduced state of PRL (zeige PRL Antikörper) and thus regulates the biological function of PRL (zeige PRL Antikörper).
Studies indicate that PRL-1 (zeige PLRG1 Antikörper) and PRL-2 (zeige PTP4A2 Antikörper) and PRL-3 are oncogenes and belong to the few phosphatases that lead to the development of cancer.
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.
protein tyrosine phosphatase type IVA 1
, protein tyrosine phosphatase type IVA, member 1
, Protein tyrosine phosphatase type IVA 1
, protein-tyrosine phosphatase 4a1
, protein-tyrosine phosphatase of regenerating liver 1
, protein tyrosine phosphatase type IVA protein 1
, protein tyrosine phosphatase 4a1