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Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1. Zusätzlich bieten wir Ihnen Protein Geranylgeranyltransferase Type I, beta Subunit Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal PGGT1B Primary Antibody für ELISA, WB - ABIN562193
Iguchi, Katsuno, Niwa, Yamada, Sone, Waza, Adachi, Tanaka, Nagata, Arimura, Watanabe, Kaibuchi, Sobue: TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases. in The Journal of biological chemistry 2009
Human Monoclonal PGGT1B Primary Antibody für IF, IHC (p) - ABIN562194
Lee, Chang, Trinh, Tu, White, Davies, Bergo, Fong, Lowry, Young: Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. in Human molecular genetics 2010
our study showed, for the first time, that HIF-1alpha (zeige HIF1A Antikörper) was regulated by protein prenylation transferase GGTI and mediated the effect of GGTI on glioma cell migration and invasion
RNAi knockdown of GGTase-Ibeta inhibited invasion, disrupted F-actin organization and decreased the level of cofilin (zeige CFL1 Antikörper) in PC-3 (zeige PCSK1 Antikörper) cells.
results suggest that geranylgeranylation of RhoA (zeige RHOA Antikörper) is critical for cancer cell invasion
Targeting GGTase-I activates RHOA (zeige RHOA Antikörper) and leads to increased macrophage reverse cholesterol transport and reduced atherosclerosis development despite a significant increase in inflammation.
Both Fntb and Pggt1b are required for the homeostasis of skin keratinocytes.
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994
protein geranylgeranyltransferase type I, beta subunit
, geranylgeranyl transferase type I subunit beta
, geranylgeranyl transferase type-1 subunit beta
, geranylgeranyltransferase type I beta subunit
, type I protein geranyl-geranyltransferase subunit beta
, geranylgeranyltransferase type 1 beta
, geranylgeranyltransferase type I (GGTase-I)