-
High lipocalin-type prostaglandin D synthase expression is associated with Spontaneous intracranial hypotension.
-
Measurement of serum BTP can be a reliable tool for detecting kidney function in neonates.
-
Thus, our results suggest decreased NK cell-mediated eosinophil regulation, possibly through an increased level of PGD2, as a previously unrecognized link between PG dysregulation and eosinophilic inflammation in CRS.
-
These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS expression and subsequent PGD2 production in the tumor endothelial cells (ECs). This PGD2 acts as a negative regulator of the tumorigenic changes in tumor ECs.
-
The cut off value for betaTP in the diagnosis and follow-up of cerebrospinal fluid leaks should be modified depending on the type of secretion (sample type), for a better diagnostic accuracy
-
Serum levels of beta trace protein and beta 2 microglobulin can be used to predict residual kidney function in hemodialysis patients.
-
BTP and B2M levels are less affected than serum by amputation, and should be considered for future study of GFR estimation
-
Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function
-
levels of L-PGDS in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.
-
Given that uPGDS levels fall after treatment of LN, uPGDS may be used to monitor the efficacy of therapy. It can also differentiate patients with active nephritis and active non renal lupus.
-
PTGDS mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.
-
Expression of MR and prostaglandin D2 synthase is strongly correlated in adipose tissues from obese patients.
-
involved in pathogenesis of androgenetic alopecia [review]
-
These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.
-
These results suggest that L-PGDS acted as a scavenger of biliverdin, which is a molecule not found in normal CSF.
-
Lipocalin-type prostaglandin D2 (PGD2) synthase (L-PGDS) interacts intracellularly with the G protein-coupled receptor DP1 in an agonist-independent manner.
-
Among NSTE-ACS patients, BTP and CysC were superior to conventional renal parameters for predicting MB, and improved clinical stratification for hemorrhagic risk.
-
Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase.
-
betaTP, beta2M, CysC, and creatinine differ in their associations with demographic and clinical factors, suggesting variation in their non-glomerular filtration rate determinants.
-
All-cause and cardiovascular mortality are strongly associated with beta-trace protein marker levels and beta-microglobulin in a representative sample of US adults.