Prostaglandin D2 Synthase 21kDa (Brain) Proteine (PTGDS)

The protein encoded by PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). Zusätzlich bieten wir Ihnen PTGDS Kits (9) und PTGDS Antikörper (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PTGDS 5730 P41222
Maus PTGDS PTGDS 19215 O09114
PTGDS 25526 P22057
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Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$385.00
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$688.00
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,370.50
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,377.83
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Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,377.83
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Hefe Cat His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,383.33
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,383.33
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Hefe REACT_Bear His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,383.33
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Hefe Schaf His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,383.33
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Hefe Pongo pygmaeus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,387.00
Details

PTGDS Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Rat (Rattus)

Weitere Proteine zu Prostaglandin D2 Synthase 21kDa (Brain) (PTGDS) Interaktionspartnern

Human Prostaglandin D2 Synthase 21kDa (Brain) (PTGDS) Interaktionspartner

  1. Thus, our results suggest decreased NK cell-mediated eosinophil regulation, possibly through an increased level of PGD2, as a previously unrecognized link between PG dysregulation and eosinophilic inflammation in CRS (zeige CARS Proteine).

  2. These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS expression and subsequent PGD2 production in the tumor endothelial cells (ECs). This PGD2 acts as a negative regulator of the tumorigenic changes in tumor ECs.

  3. Serum levels of beta trace protein and beta 2 microglobulin (zeige B2M Proteine) can be used to predict residual kidney function in hemodialysis patients.

  4. BTP and B2M (zeige B2M Proteine) levels are less affected than serum by amputation, and should be considered for future study of GFR (zeige RAPGEF5 Proteine) estimation

  5. Hematopoietic prostaglandin D synthase (zeige HPGDS Proteine) defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

  6. levels of L-PGDS in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.

  7. PTGDS mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.

  8. Expression of MR and prostaglandin D2 synthase is strongly correlated in adipose tissues from obese patients.

  9. These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.

  10. These results suggest that L-PGDS acted as a scavenger of biliverdin, which is a molecule not found in normal CSF (zeige CSF2 Proteine).

Zebrafish Prostaglandin D2 Synthase 21kDa (Brain) (PTGDS) Interaktionspartner

  1. results indicate that non-mammalian and mammalian L-PGDS genes evolved from the same ancestral gene and that the non-mammalian L-PGDS homologue was the primordial form of L-PGDS

Mouse (Murine) Prostaglandin D2 Synthase 21kDa (Brain) (PTGDS) Interaktionspartner

  1. These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS expression and subsequent PGD2 production in the tumor endothelial cells (ECs). This PGD2 acts as a negative regulator of the tumorigenic changes in tumor ECs.

  2. Exposure of macrophages to cyclooxygenase (COX-2) inhibitors RhoA (zeige RHOA Proteine) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 receptors or the hepatocyte growth factor (HGF (zeige HGF Proteine)) receptor c-Met (PHA (zeige LBR Proteine)-665752), reversed EMT (zeige ITK Proteine) inhibition by the conditioned medium

  3. Ptgds is targeted and repressed by the CUL4B (zeige CUL4B Proteine)/PRC2 complex.

  4. Thermodynamic and nuclear magnetic resonance analyses demonstrated that L-PGDS binds to nicotinamide coenzymes, including NADPH, NADP(+), and NADH.

  5. Prostaglandin D2 synthase is a novel MR target gene in adipocytes.

  6. When prostaglandin D2 synthase is upregulated it participates in the regulation of peripheral nervous system myelination.

  7. expression of L-PGDS in mouse lungs decreased neutrophilic infiltration, ameliorating lung inflammation in mice.

  8. Silencing of PTGDS also alleviated H-rev107 (zeige HRASLS Proteine)-mediated suppression of cell migration and invasion

  9. In this report, we show for the first time that alteration of the PTGDS-governed PGD2 pathway disturbs testicular migration in mice.

  10. Data indicate a PLA2G3 (zeige PLA2G3 Proteine)-lipocalin (zeige APOD Proteine)-type PGD2 synthase (L-PGDS)-PGD2 receptor DP1 (zeige PTGDR Proteine) loop that drives mast cell maturation.

Cow (Bovine) Prostaglandin D2 Synthase 21kDa (Brain) (PTGDS) Interaktionspartner

  1. L-PGDS may have a role in cattle fertilization.

PTGDS Protein Überblick

Protein Überblick

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Genbezeichner und Symbole assoziert mit PTGDS

  • prostaglandin D2 synthase (PTGDS)
  • lipocalin 15 (lcn15)
  • hematopoietic prostaglandin D synthase (HPGDS)
  • prostaglandin D2 synthase 21kDa (brain) (PTGDS)
  • prostaglandin D2 synthase L homeolog (ptgds.L)
  • prostaglandin D2 synthase (brain) (Ptgds)
  • prostaglandin D2 synthase (Ptgds)
  • prostaglandin D2 synthase a (ptgdsa)
  • 21kDa Protein
  • cerebrin-28 Protein
  • cpl-1 Protein
  • im:7160217 Protein
  • l-pgds Protein
  • lpgds Protein
  • pds Protein
  • pgd2 Protein
  • pgds Protein
  • pgds2 Protein
  • PH2DISO Protein
  • PTGDS Protein
  • Ptgs3 Protein
  • XlCpl1 Protein
  • zgc:153919 Protein
  • zgc:194505 Protein
  • zgc:194526 Protein

Bezeichner auf Proteinebene für PTGDS

PGD2 synthase , beta-trace protein , cerebrin-28 , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin D synthase , lipocalin-type prostaglandin-D synthase , prostaglandin D synthase , prostaglandin-D2 synthase , prostaglandin-H2 D-isomerase , prostaglandin D2 synthase, hematopoietic , prostaglandin D2 synthase 21kDa (brain) , Prostaglandin D Synthase , lipocalin , prostaglandin D2 synthase, brain , GST class-sigma , H-PGDS , glutathione S-transferase , glutathione-dependent PGD synthase , glutathione-dependent PGD synthetase , glutathione-requiring prostaglandin D synthase , prostaglandin-D synthase , prostaglandin D2 synthase (21 kDa, brain) , PGDS , PGDS2 , Prostaglandin D synthase , lipocalin-type prostaglandin D2 synthase , prostaglandin D2 synthase a

GENE ID SPEZIES
5730 Homo sapiens
751703 Danio rerio
705227 Macaca mulatta
100353701 Oryctolagus cuniculus
749402 Pan troglodytes
397884 Xenopus laevis
395863 Gallus gallus
19215 Mus musculus
25526 Rattus norvegicus
403740 Canis lupus familiaris
493852 Felis catus
100067921 Equus caballus
397456 Sus scrofa
286858 Bos taurus
443192 Ovis aries
101926100 Macaca fascicularis
555483 Danio rerio
Ausgewählte Anbieter für PTGDS Proteine (PTGDS)
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