anti-Programmed Cell Death 1 (PDCD1) Antikörper

May have a role in the regulation of spermatogenesis.. Zusätzlich bieten wir Ihnen PD-1 Proteine (91) und PD-1 Kits (26) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDCD1 5133 Q15116
PDCD1 301626  
PDCD1 18566 Q02242
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Top anti-PD-1 Antikörper auf antikoerper-online.de

Showing 10 out of 661 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml Lane 1: JURKAT Whole Cell Lysate at 40ug Lane 2: Human Placenta Tissue Lysate at 50ug Predicted bind size: 32KD Observed bind size: 38KD Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml WB: Recombinant Human PD1 Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Maus Ziege PE FACS Detection of PD-1 in Mouse CD4+ T-Cells by Flow Cytometry. Mouse CD4+ T-cells were stained with Goat Anti-Mouse PD-1 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$351.90
Details
Human Ziege Biotin ELISA (Detection), FACS, WB Detection of PD-1 in Human PBMCs treated with PHA by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ug/mL PHA overnight were stained with Goat Anti-Human PD-1 Biotinylated Antigen Affinity-purified Polyclonal Antibody. 50 μg Anmelden zum Anzeigen 8 bis 9 Tage
$451.95
Details
Maus Ziege Unkonjugiert CyTOF, FACS, IHC, WB PD-1 in Mouse Spleen. PD-1 was detected in perfusion fixed frozen sections of mouse spleen using Goat Anti-Mouse PD-1 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm in splenocytes. PD-1 in Mouse Thymus. PD-1 was detected in perfusion fixed frozen sections of mouse thymus using 15 µ 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$440.45
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD279 expression in THP1 (A), HepG2 (B), mouse liver (C), H9C2 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185400 (0.6µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Maus Unkonjugiert EIA, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Maus Hamster Biotin FACS 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$308.00
Details
Maus Hamster Unkonjugiert FACS 0.25 mg Anmelden zum Anzeigen 6 bis 8 Tage
$379.50
Details
Human Maus Unkonjugiert CyTOF, FACS, WB Detection of PD-1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ng/mL PHA for 2 days were stained with Mouse Anti-Human PD-1 Monoclonal Antibody. Detection of Human PD-1 by Western Blot. Western blot shows lysates of HEK293 human embryonic kidney cell line either mock transfected or transfected with human PD-1. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human PD-1 Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$346.15
Details

PDCD1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-PD-1 Antikörper

  1. Human Monoclonal PD-1 Primary Antibody für BR, FACS - ABIN2689142 : Bennett, Luxenberg, Ling, Wang, Marquette, Lowe, Khan, Veldman, Jacobs, Valge-Archer, Collins, Carreno: Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal PD-1 Primary Antibody für ELISA (Detection), FACS - ABIN4899871 : Sakthivel, Ramanujam, Wang, Pirskanen, Lefvert: Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. in Journal of neuroimmunology 2008 (PubMed)
    Show all 7 Pubmed References

  3. Mouse (Murine) Monoclonal PD-1 Primary Antibody für BR, FACS - ABIN2689141 : Nishimura, Agata, Kawasaki, Sato, Imamura, Minato, Yagita, Nakano, Honjo: Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes. in International immunology 1997 (PubMed)
    Show all 7 Pubmed References

  4. Human Polyclonal PD-1 Primary Antibody für IHC, ELISA - ABIN1002980 : Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal PD-1 Primary Antibody für IHC, ELISA - ABIN1002981 : Ishida, Agata, Shibahara, Honjo: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. in The EMBO journal 1992 (PubMed)
    Show all 4 Pubmed References

  6. Mouse (Murine) Polyclonal PD-1 Primary Antibody für CyTOF, FACS - ABIN4899873 : Kasagi, Kawano, Okazaki, Honjo, Morinobu, Hatachi, Shimatani, Tanaka, Minato, Kumagai: Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal PD-1 Primary Antibody für ICC, FACS - ABIN438813 : Dorrell, Abraham, Lanxon-Cookson, Canaday, Streeter, Grompe: Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. in Stem cell research 2009 (PubMed)
    Show all 2 Pubmed References

  8. Mouse (Murine) Monoclonal PD-1 Primary Antibody für IHC (fro), FACS - ABIN2479661 : Yamaoka, Furusawa, Fujimoto, Iguchi, Kumai: Muscle spindles in the mylohyoid muscle of rats. in International journal of oral and maxillofacial surgery 1992 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal PD-1 Primary Antibody für FACS - ABIN2479652 : Ochonisky, Chosidow, Kuentz, Man, Fraitag, Pelisse, Revuz: Cogan's syndrome. An unusual etiology of urticarial vasculitis. in Dermatologica 1992 (PubMed)
    Show all 3 Pubmed References

  10. Human Monoclonal PD-1 Primary Antibody für FACS - ABIN2479654 : Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen PD-1 Interaktionspartner

Human Programmed Cell Death 1 (PDCD1) Interaktionspartner

  1. Report hyperprogression/reduced progression-free survival during anti-PD-1/PD-L1 (zeige CD274 Antikörper) therapy in patients with recurrent and/or metastatic head and neck squamous cell carcinoma.

  2. Data indicate clinical responses to PD-1 blockade occur in prostate cancer patients progressing on enzalutamide.

  3. Results showed that high CTLA4 (zeige CTLA4 Antikörper) but low PD-1 expression were associated with a poor overall survival of patients with breast cancer.

  4. Surface expression of PD-1 on CD4 (zeige CD4 Antikörper)+ T cells has a prognostic value in non-small cell lung cancer patients, as high expression of PD-1 is associated with a shorter progression-free survival and overall survival.

  5. results not only provide a foundation for further assessment of PD-L1 (zeige CD274 Antikörper) immunohistochemistry as a predictive marker for anti-PD-1 therapy in colorectal carcinoma

  6. Blimp-1 (zeige PRDM1 Antikörper) binds to the promoters of PD-1 and TIGIT (zeige TIGIT Antikörper) and positively regulates their expression in patients with acute myeloid leukemia (zeige BCL11A Antikörper).

  7. high PD-L1 (zeige CD274 Antikörper) expression by tumor cells was associated with favorable prognosis, whereas an increased number of PD-1+ TILs was correlated with poor prognosis in thymic carcinoma.

  8. The majority of primary penile penile squamous cell carcinoma (SqCC) tumors express PD-L1 (zeige CD274 Antikörper), which is associated with high-risk clinicopathologic features and poor clinical outcome. These data provide a rational basis for further investigation of anti-PD-1 and anti-PD-L1 (zeige CD274 Antikörper) immunotherapeutics in patients with advanced penile SqCC

  9. Of several immunotherapies being investigated, antibodies that target the programmed cell death protein-1 (nivolumab and pembrolizumab) and cytotoxic T-lymphocyte antigen-4 (zeige CTLA4 Antikörper) (ipilimumab) immune checkpoint pathways are among the most promising for patients with Small cell lung cancer (SCLC), and are the focus of this review.

  10. In this review, we discuss deepening insights into human genetics and our understanding of the interface with rheumatoid arthritis pathogenesis providing a strong rationale for exploiting the co-inhibitory receptor programmed cell death-1 signaling pathway as a better approach for the treatment of this chronic, often progressive destructive joint disease.

Mouse (Murine) Programmed Cell Death 1 (PDCD1) Interaktionspartner

  1. Data (including data from studies in transgenic/knockout mice) suggest that T-cell expression of Mirn155 is required to limit melanoma growth; miR (zeige MLXIP Antikörper)-155, Pdcd1, Pdcd1l1 (zeige CD274 Antikörper), and Ctla4 (zeige CTLA4 Antikörper) appear to regulate overlapping pathways promoting antitumor immunity. [Mirn155 = microRNA 155; Pdcd1 = programmed cell death 1 protein; Pdcd1l1 (zeige CD274 Antikörper) = programmed cell death 1 ligand 1 (zeige CD274 Antikörper) protein; Ctla4 (zeige CTLA4 Antikörper) = cytotoxic T-lymphocyte-associated protein 4 (zeige CTLA4 Antikörper)]

  2. PD-1 plays a vital role in brain inflammation via regulation of Fgl-2 (zeige FGL2 Antikörper) after ICH (zeige ACE Antikörper), and that manipulation of PD-1 might be a promising therapeutical target in ICH (zeige ACE Antikörper).

  3. We identified PD-1 to be specifically expressed in PLZF (zeige ZBTB16 Antikörper)(+) ILCp and revealed that the timing and order of expression of the transcription factors NFIL3 (zeige NFIL3 Antikörper), ID2, and TCF-1 (zeige HNF1A Antikörper) was critical. Importantly, induction of ILC (zeige CCL27 Antikörper) lineage commitment required only transient expression of NFIL3 (zeige NFIL3 Antikörper) prior to ID2 and TCF-1 (zeige HNF1A Antikörper) expression.

  4. The identification of the role for PD-1 in regulating B cell-dependent antitumor immunity to Tn antigen highlights an opportunity to develop new therapeutic strategies targeting tumor-associated carbohydrate antigens

  5. These findings suggest that PD-1 pathway blockade may reverse adaptive immune resistance following cyclic dinucleotide treatment, enhancing both local and systemic antitumor immunity.

  6. data suggest that increased expression of checkpoint blockade molecules PD-1 and CTLA-4 (zeige CTLA4 Antikörper) on donor T cells is not sufficient to prevent GvHD, and that cooperation between checkpoint blockade signaling by host cells and donor Tregs is necessary to limit GvHD in allo-HSCT recipients

  7. PD-1 Blockade Promotes Epitope Spreading in Anticancer CD8 (zeige CD8A Antikörper)(+) T Cell Responses by Preventing Fratricidal Death of Subdominant Clones To Relieve Immunodomination

  8. Adoptive transfer of murine T cells expressing a chimeric-PD1-Dap10 (zeige HCST Antikörper) receptor may induce a preferential cytokine profile and T-cell differentiation phenotype for anti-lymphoma therapies.

  9. soluble PD-1 is elevated in critical illness and may represent a potential biomarker for Acute respiratory distress syndrome.

  10. Together, our results suggest an important role of PD-1 in glioma-induced immune escape, and provide translational evidence for the use of PD-1 blocking antibodies in human malignant gliomas.

Rhesus Monkey Programmed Cell Death 1 (PDCD1) Interaktionspartner

  1. Data show that CTLA-4 (zeige CTLA4 Antikörper)(+)PD-1(-) memory CD4 (zeige CD4 Antikörper)(+) T cells, which share phenotypic markers with regulatory T cells, were enriched in SIV DNA in blood, lymph nodes (LN), spleen, and gut (zeige GUSB Antikörper), and contained replication-competent and infectious virus.

  2. Compared to before immunosuppression, PD-1 expression increased at reactivation. Increased T cells before zoster is likely due to virus reactivation.

  3. A PD-1(high) phenotype is associated with accelerated in vivo CD8 (zeige CD8A Antikörper) T cell turnover in SIV-infections, especially within the SIV-specific CD8 (zeige CD8A Antikörper) T cell pool.

  4. High levels of PD-1 expression on CD4 (zeige CD4 Antikörper)(+) T cells in lymph nodes of rhesus macaques can serve as a valuable marker to identify T follicular helper cells.

  5. Data indicate that PD-1 expression is increased as a result of T cell activation during a primary immune response as well as during persistent immune activation in macaques.

  6. PD-1 can serve as a sensitive indicator of persistent, low-level virus replication

PD-1 (PDCD1) Antigen-Profil

Protein Überblick

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Genbezeichner und Symbole assoziert mit PDCD1

  • programmed cell death 1 (PDCD1) Antikörper
  • programmed cell death 1 (Pdcd1) Antikörper
  • CD279 Antikörper
  • hPD-1 Antikörper
  • hPD-l Antikörper
  • Ly101 Antikörper
  • PD-1 Antikörper
  • PD1 Antikörper
  • Pdc1 Antikörper
  • SLEB2 Antikörper

Bezeichner auf Proteinebene für PDCD1

programmed cell death protein 1 , protein PD-1 , programmed cell death 1 , programmed death 1 , mPD-1

GENE ID SPEZIES
5133 Homo sapiens
301626 Rattus norvegicus
424913 Gallus gallus
613842 Bos taurus
18566 Mus musculus
486213 Canis lupus familiaris
100135775 Macaca mulatta
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