Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) ELISA Kits

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Zusätzlich bieten wir Ihnen KCNJ2 Antikörper (93) und KCNJ2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human KCNJ2 KCNJ2 3759 P63252
Anti-Ratte KCNJ2 KCNJ2 29712 Q64273
Anti-Maus KCNJ2 KCNJ2 16518 P35561
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Weitere ELISA Kits für KCNJ2 Interaktionspartner

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. We report a novel KCNJ2 sequence variant (p.Y145C) in a family with diagnosed Andersen-Tawil syndrome.

  2. Combined inhibition of IKr and IKur produced a synergistic anti-arrhythmic effect in both forms of SQT3. In conclusion, this study provides mechanistic insights into atrial proarrhythmia with SQT3 Kir2.1 mutations and highlights possible pharmacological strategies for management of SQT3-linked AF.

  3. Data suggest that an R204A mutation disrupts the characteristic cytoplasmic domain subunit interface salt bridges in Kir2.1 reducing apparent sensitivity of channel activity to ligand PIP2 (phosphatidylinositol bisphosphate).

  4. These findings suggest that KCNJ2 plays an important role in the pathophysiology of Thyrotoxic Periodic Paralysis in Korean Graves' Disease patients with Thyrotoxic Periodic Paralysis .

  5. Nav1.5 (zeige SCN5A ELISA Kits) N-terminal domain binding to alpha1-syntrophin (zeige SNTA1 ELISA Kits) increases membrane density of human Kir2.1, Kir2.2 (zeige KCNJ12 ELISA Kits) and Nav1.5 (zeige SCN5A ELISA Kits) channels

  6. Kir2.1 may participate in macrophage maturation and differentiation, and play a key role in lipid uptake and foam cell formation through modulating the expression of scavenger receptors.

  7. a Korean family with Andersen-Tawil syndrome with a G215D mutation of the KCNJ2 gene revealed by diagnostic exome sequencing, is reported.

  8. Chloroethylclonidine interact with Kir2.1 channels in the cytoplasmic pore.

  9. Variability has been found in a three-generation family with Pierre Robin sequence, acampomelic campomelic dysplasia, and intellectual disability due to a novel approximately 1 Mb deletion upstream of SOX9 (zeige SOX9 ELISA Kits), and including KCNJ2 and KCNJ16 (zeige KCNJ16 ELISA Kits).

  10. Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 (zeige KCNN3 ELISA Kits) and KCNJ2 Genes and CACNG8 (zeige CACNG8 ELISA Kits)-Linked Left Ventricular Dysfunction

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. Following differentiation with LPS (zeige TLR4 ELISA Kits) or a combination of LPS (zeige TLR4 ELISA Kits) and IFN-gamma (zeige IFNG ELISA Kits) microglia exhibited high KV 1.3 current densities ( approximately 50 pA/pF at 40 mV) and virtually no KCa (zeige CSN3 ELISA Kits) 3.1 and Kir (zeige GEM ELISA Kits) currents, while microglia differentiated with IL-4 (zeige IL4 ELISA Kits) exhibited large Kir (zeige GEM ELISA Kits) 2.1 currents ( approximately 10 pA/pF at -120 mV). KCa (zeige CSN3 ELISA Kits) 3.1 currents were generally low

  2. Cellular electrophysiology assays of mouse Kir2.1 and human Kir2.2 indicated that, consistent with simulations, the Leu residue increased the channel responses to phosphatidylinositol diphosphate (PIP2) through increased binding affinity and faster activation kinetics, and the deactivation kinetics decreased upon PIP2 inhibition.

  3. histone H4 hyperacetylation induced by Class I HDACs inhibitors promoted the expression profiles of potassium channels (Kcnj2, Kcnj3 (zeige KCNJ3 ELISA Kits), Kcnj5 (zeige KCNJ5 ELISA Kits), Kcnj11 (zeige KCNJ11 ELISA Kits), and Kcnh2 (zeige KCNH2 ELISA Kits))

  4. Our results support the concept that endothelial cell Kir2 channels boost vasodilatory signals that are generated by Ca(2 (zeige CA2 ELISA Kits)+) -dependent activation of IK and SK channels.

  5. Results suggest that a promyogenic cell adhesion molecule (zeige MCAM ELISA Kits) Cdo (zeige CDO1 ELISA Kits) signaling is critical for Inward rectifier potassium channel Kir2.1 activities in the induction of myogenic differentiation.

  6. The data suggest that microglial Kir2.1 channels may represent novel therapeutic targets to inhibit excessive reactive oxygen species production by primed microglia in brain pathology.

  7. Three pairs of weak interactions precisely regulate the G-loop gate of Kir2.1 channel.

  8. Suggest that Kir2.1 channels, in part, account for hyperpolarization and associated absence of tone in urinary bladder arterioles.

  9. This finding represents the first functional evidence for a significant role of the dystrophin (zeige DMD ELISA Kits)-associated protein complex in the regulation of Kir2.x channels.

  10. Intracellular Mg(2 (zeige MCOLN1 ELISA Kits)+) and SPM (zeige NPC1 ELISA Kits) therefore may have a synergistic action on the pore-blocking effect, presumably via prohibition of the outward exit of the higher-affinity blocking SPM (zeige NPC1 ELISA Kits) by the lower-affinity Mg(2 (zeige MCOLN1 ELISA Kits)+).

Cow (Bovine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. Hypoxic stress up-regulates Kir2.1 expression and facilitates cell proliferation in brain capillary endothelial cells.

  2. Kir2.1 may mediate native Kir (zeige GEM ELISA Kits) currents responsible for setting resting membrane potential in bovine parotid cells and might be, at least in part, involved in spontaneous secretion in ruminant parotid glands.

Rabbit Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Interaktionspartner

  1. There were substantial transmural gradients in Cav1.2 (zeige CACNA1C ELISA Kits), KChIP2 (zeige KCNIP2 ELISA Kits), ERG (zeige KCNH2 ELISA Kits), KvLQT1 (zeige KCNQ1 ELISA Kits), Kir2.1, NCX1 (zeige SLC8A1 ELISA Kits), SERCA2a (zeige ATP2A2 ELISA Kits) and RyR2 (zeige RYR2 ELISA Kits) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

KCNJ2 Antigen-Profil

Beschreibung des Gens

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Genbezeichner und Symbole assoziert mit KCNJ2

  • potassium voltage-gated channel subfamily J member 2 (KCNJ2) Antikörper
  • potassium voltage-gated channel subfamily J member 2 (Kcnj2) Antikörper
  • potassium inwardly-rectifying channel, subfamily J, member 2 (Kcnj2) Antikörper
  • ATFB9 Antikörper
  • HHBIRK1 Antikörper
  • HHIRK1 Antikörper
  • IRK-1 Antikörper
  • IRK1 Antikörper
  • Kcnf1 Antikörper
  • KCNJ2 Antikörper
  • Kir2.1 Antikörper
  • LQT7 Antikörper
  • SQT3 Antikörper

Bezeichner auf Proteinebene für KCNJ2

IRK-1 , inward rectifier K(+) channel Kir2.1 , inward rectifier potassium channel 2 , potassium channel, inwardly rectifying subfamily J member 2 , cardiac inward rectifier potassium channel , hIRK1 , inward rectifier K+ channel KIR2.1 , RBL-IRK1 , BIK , inward rectifier potassium channel cIRK1 , cardiac inward rectifier KIR2.1 , inwardly rectifying potassium channel Kir2.1 , inward rectifier potassium channel Kir2.1 , inwardly-rectifying potassium channel Kir2.1

397293 Sus scrofa
3759 Homo sapiens
29712 Rattus norvegicus
16518 Mus musculus
281883 Bos taurus
396328 Gallus gallus
403717 Canis lupus familiaris
100135566 Cavia porcellus
100008987 Oryctolagus cuniculus
574189 Macaca mulatta
Haben Sie etwas anderes gesucht?