anti-Poly-U Binding Splicing Factor 60KDa (PUF60) Antikörper

PUF60 encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. Zusätzlich bieten wir Ihnen PUF60 Proteine (9) und PUF60 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PUF60 67959 Q3UEB3
PUF60 84401  
PUF60 22827 Q9UHX1
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Top anti-PUF60 Antikörper auf antikoerper-online.de

Showing 10 out of 133 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PUF60 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Hela cell lysate Host: Rabbit <br /> Target Name: PUF60 <br /> Sample Tissue: Human Fetal Lung <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184855 (1µg/ml) staining of A431 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB ICC/IF Image PUF60 antibody detects PUF60 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PUF60 protein stained by PUF60 antibody , diluted at 1:500. Red: phalloidin, a cytoskeleton marker, diluted at 1:200. Blue: Hoechst 33342 staining. Scale bar = 10 μm. WB Image Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image Sample(30 μg of whole cell lysate) A:Hep G2, B:MOLT4, C: Raji , 7.5% SDS PAGE antibody diluted at 1:500 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using PUF60, antibody at 1:500 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Huhn Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Huhn Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: PUF60 Antibody [NBP2-20007] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: PUF60 Antibody  - Paraffin-embedded U251 xenograft. PUF60 antibody dilution: 1:500. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details

PUF60 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PUF60 Antikörper

  1. Human Polyclonal PUF60 Primary Antibody für ELISA, WB - ABIN249695 : Liu, He, Collins, Ge, Libutti, Li, Egly, Levens: The FBP interacting repressor targets TFIIH to inhibit activated transcription. in Molecular cell 2000 (PubMed)

Weitere Antikörper gegen PUF60 Interaktionspartner

Human Poly-U Binding Splicing Factor 60KDa (PUF60) Interaktionspartner

  1. PUF60 auto-antibodies are detected in the sera of early-stage colon cancer patients and level decreases after surgery.

  2. These results confirm that PUF60 is a major driver for the developmental, craniofacial, skeletal and cardiac phenotypes associated with the 8q24.3 microdeletion

  3. Heterozygote loss-of-function variants in PUF60 cause a phenotype comprising growth/developmental delay and craniofacial, cardiac, renal, ocular and spinal anomalies.

  4. Mutations in PUF60 gene is associated with idiopathic hypereosinophilic syndrome.

  5. Concomitant over expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer cells.

  6. Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.

  7. High FBP-interacting repressor expression is associated with hepatocellular carcinoma.

  8. The interaction between SAP155 and FIR/FIRDeltaexon2 not only integrates cell-cycle progression and c-Myc transcription by modifying P27 and P89 expression.

  9. Haploinsufficiency of each of SCRIB (zeige SCRIB Antikörper) or PUF60 contribute uniquely to specific endophenotypes (e.g., coloboma, heart defects), and binary interaction potentially exacerbates other aspects of the clinical pathology of individuals with 8q24.3 deletion.

  10. Circulating FIR (zeige FARP2 Antikörper) variant mRNA in the peripheral blood of cancer patients were significantly overexpressed compared to that in healthy volunteers.

PUF60 Antigen-Profil

Protein Überblick

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit PUF60

  • poly-U binding splicing factor 60 (Puf60) Antikörper
  • poly(U) binding splicing factor 60 (PUF60) Antikörper
  • 2410104I19Rik Antikörper
  • 2810454F19Rik Antikörper
  • FIR Antikörper
  • RoBPI Antikörper
  • Siahbp1 Antikörper

Bezeichner auf Proteinebene für PUF60

60 kDa poly(U)-binding-splicing factor , fuse-binding protein-interacting repressor , poly(U)-binding-splicing factor PUF60 , FBP interacting repressor , RNA-binding protein Siah-BP , Ro ribonucleoprotein-binding protein 1 , poly-U binding splicing factor 60K , pyrimidine tract binding splicing factor , siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1 , siah-binding protein 1 , FUSE-binding protein-interacting repressor , Siah binding protein 1

GENE ID SPEZIES
67959 Mus musculus
84401 Rattus norvegicus
22827 Homo sapiens
607245 Canis lupus familiaris
512824 Bos taurus
100174042 Pongo abelii
Ausgewählte Anbieter für anti-PUF60 (PUF60) Antikörper
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