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PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen PEAR1 Proteine (7) und PEAR1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal PEAR1 Primary Antibody für CyTOF, FACS - ABIN4899612
Faraday, Yanek, Yang, Mathias, Herrera-Galeano, Suktitipat, Qayyum, Johnson, Chen, Tofler, Ruczinski, Friedman, Gylfason, Thorsteinsdottir, Bray, ODonnell, Becker, Becker: Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. in Blood 2011
Show all 2 Pubmed References
PEAR1 rs12041331 polymorphism may influence ticagrelor pharmacodynamics
DNA methylation (zeige HELLS Antikörper) at 4 different loci of PEAR1 during in vitro megakaryopoiesis, was studied.
In a White population, we could not replicate previous reports from experimental studies or obtained in patients suggesting that PEAR1 might be a susceptibility gene for cardiovascular complications
PEAR1 genetic variations were strongly associated with platelet reactivity in a Chinese patient population with coronary heart disease undergoing dual antiplatelet therapy with aspirin and clopidogrel.
A considerable portion of Chinese ischemic stroke patients are insensitive to aspirin treatment, which may be correlated with the MDR1 (zeige TBC1D9 Antikörper) C3435T, TBXA2R (zeige TBXA2R Antikörper) (rs1131882), and PLA2G7 (zeige Lp-PLA2 Antikörper) (rs1051931-rs7756935) polymorphisms.
Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.
Results suggest that genetic variation of PEAR1 is a significant determinant of endothelial function through pathways implicated in cardiovascular disease.
FcepsilonRI (zeige FCER1G Antikörper) alpha-chain (zeige FCGRT Antikörper) is an activating platelet endothelium aggregation receptor 1 (PEAR1) ligand.
genetic variability of GAS6 (zeige GAS6 Antikörper) and PEAR1 genes may be associated with platelet hyperaggregability
A common genetic variant in PEAR1 (rs12041331) reproducibly influenced platelet aggregation in aspirin-treated patients with coronary artery disease.
Jedi-1 signals through recruitment of GULP (zeige GULP1 Antikörper), which promotes phagocytosis through a noncanonical phosphoclathrin-dependent mechanism.
These results indicated that both Jedi-1 and MEGF10 (zeige MEGF10 Antikörper) can mediate phagocytosis independently through the recruitment of Syk (zeige SYK Antikörper).
Jedi is involved in the fine regulation of the early stages of hematopoietic differentiation, presumably through the Notch (zeige NOTCH1 Antikörper) signaling pathway.
a cellular and molecular mechanism by which neuronal corpses are culled during dorsal root ganglia development involves Jedi protein
PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005
platelet endothelial aggregation receptor 1
, multiple EGF-like-domains 12
, platelet endothelial aggregation receptor 1-like
, multiple EGF-like domains protein 12
, multiple epidermal growth factor-like domains protein 12
, jagged and Delta protein
, protein Jedi