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The protein encoded by PLTP is one of at least two lipid transfer proteins found in human plasma. Zusätzlich bieten wir Ihnen PLTP Antikörper (84) und PLTP Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.
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Ehlers, Larson, Rasmussen, Park, Lee: High-density lipoprotein metabolism in human apolipoprotein B(100) transgenic/brown adipose tissue deficient mice: a model of obesity-induced hyperinsulinemia. in Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2011
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identification and characterization of CaM-binding domain of non-specific lipid transfer proteins
PLTP activity did not affect this metric. Thus, deviations in PLTP activity from the wild-type level reduce HDL (zeige HSD11B1 ELISA Kits) mass and ex vivo cholesterol efflux capacity, but not the rate of macrophage cholesterol efflux to plasma or in vivo mRCT.
serum CETP (zeige CETP ELISA Kits) and PLTP activity in patients diagnosed with hypothyroidism, was examined.
PLTP may regulate cigarette smoke extract-induced IL-8 (zeige IL8 ELISA Kits) expression via the ERK1/2 (zeige MAPK1/3 ELISA Kits) signaling pathway in human pulmonary epithelial cells
LPL (zeige LCP1 ELISA Kits) and PLTP appear to be novel glioma-associated proteins and play a role in the progression of human glioma
association of PON-1 (zeige PON1 ELISA Kits) activity with PLTP activity was lost in analysis which included large HDL (zeige HSD11B1 ELISA Kits) particles
a novel association between PLTPa and PON1 (zeige PON1 ELISA Kits) activity
The domain of apolipoprotein E4 required for PLTP activation resides within its amino-terminal 1-185 region.
Elevated baseline plasma levels of PLTP are associated with an increased risk of long-term all-cause mortality in patients with diabetes and known or suspected coronary disease.
This review summarizes the recent progresses made in the PLTP research field and focuses on the complexity of the implication of PLTP in obesity, insulin (zeige INS ELISA Kits) resistance and type 2 diabetes mellitus. [review]
Elevated plasma PLTP activity may predict an increased risk of T2DM in men
this work reports a physiological role for PLTP in the polarization of CD4 (zeige CD4 ELISA Kits)(+) T cells toward the pro-inflammatory Th1 (zeige HAND1 ELISA Kits) phenotype.
these findings elucidated that PLTP repressed LPS (zeige TLR4 ELISA Kits) induced inflammation due to extracellular LPS (zeige TLR4 ELISA Kits) binding capability, and the protective effects were not related to HDL (zeige HSD11B1 ELISA Kits) pool size in mice.
Data presented a novel model to link phospholipid metabolism to APP (zeige APP ELISA Kits) processing and also suggested that PLTP played an important role in Abeta (zeige APP ELISA Kits) metabolism and would be useful to further elucidate functions of PLTP in Alzheimer's disease susceptibility.
In hepatocytes, initial recruitment of phospholipid (PL) by apoB (zeige APOB ELISA Kits):1000 leading to the formation of the PL-rich apoB (zeige APOB ELISA Kits)-containing initiation complex is mediated to a large extent by PLTP.
PLTP plays an important role in modulating the stability of atherosclerotic plaques. The receptor-interacting protein 3 (zeige RIPK3 ELISA Kits)- reactive oxygen species signal pathway could be involved in this PLTP-mediated process.
Adipocyte PLTP plays a small but significant role in plasma PLTP activity and promotes cholesterol efflux from adipose tissues.
PLTP exerts significant effects on apoA-I (zeige APOA1 ELISA Kits) lipidation and nascent HDL (zeige HSD11B1 ELISA Kits) biogenesis in hepatocytes by promoting ATP-binding cassette transporter A1 (zeige ABCA1 ELISA Kits)-mediated lipid efflux and the remodeling of nascent HDL (zeige HSD11B1 ELISA Kits) particles.
Plasma Sphingosine-1-phosphate contents were decreased by 60.1 % in PLTP knockout mice (PLTP-/-, N = 5) compared with their wild type littermates (WT, N = 5) (151.70 +/- 38.59 vs. 379.32 +/- 59.90 nmol/l, P<0.01).
Therefore we concluded that PLTP deficiency impaired cognition and aggravated AD by enhancing the generation of Abeta (zeige APP ELISA Kits) in the cortex of old mice.
Cerebrovascular oxidative stress increased in PLTP deficient mice, including increased levels of reactive oxygen species (ROS) and lipid peroxidation marker 4-hydroxy-2-nonenal (HNE) and reduced superoxide dismutase (SOD) activity.
PLTP is actively involved in lipid transfer, cholesterol efflux, HDL (zeige HSD11B1 ELISA Kits) genesis, and remodeling at the blood-brain barrier.
Results suggest that phospholipid transfer protein (PLTP) polymorphisms might be an important genetic influence on economic traits in Hanwoo (Korean cattle).
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.
phospholipid transfer protein
, BPI fold containing family E
, lipid transfer protein II
, plasma phospholipid transfer protein
, PLTP-like protein