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may play a role in phospholipase activation, production of prostaglandins, and regulation of inflammatory response [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen PLAA Antikörper (87) und PLAA Kits (37) und viele weitere Produktgruppen zu diesem Protein an.
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In both human and mouse, hypomorphic mutations in the ubiquitin adaptor protein PLAA cause an infantile-lethal neurodysfunction syndrome with seizures.
Upon damage, p97 translocates to lysosomes and there cooperates with a distinct set of cofactors including UBXD1, PLAA, and the deubiquitinating enzyme YOD1, which we term ELDR components for Endo-Lysosomal Damage Response.
This study presented that Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy.
This review provides evidence that 1,25-dihydroxy vitamin D3 stimulates PLA2 via PLAA and CaMKII, a process initiated by Pdia3/PLAA interaction, which further triggers CaMKII-dependent PLA2 activation. [review]
Function assignment to conserved residues in mammalian alkaline phosphatases.
PLAP inhibits sPLA2-triggered release of fatty acids from erythrocyte membranes
identified one stimulatory element, with Sp1 binding sites, and one inhibitory element, in exon 1 of the plaa gene
Structural basis for ubiquitin recognition by a novel domain from the human phospholipase A2-activating protein
We demonstrate that PLAA is essential for neural function, through dual roles of (1) regulating post-endocytic trafficking of signaling receptors necessary for neural development and (2) directing sorting of synaptic vesicle (SV) components during recycling, essential for synaptic function.
miR-203 may regulate expression of the novel nociceptive mediator PLAA after incision.
Phospholipase A2 activating protein is required for 1alpha,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3
may play a role in phospholipase activation, production of prostaglandins, and regulation of inflammatory response
phospholipase A-2-activating protein
, phospholipase A2-activating protein
, phospholipase A-2-activating protein-like
, DOA1 homolog
, phospholipase A2 activating protein