anti-Peripheral Myelin Protein 22 (PMP22) Antikörper

PMP22 encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Zusätzlich bieten wir Ihnen PMP22 Kits (32) und PMP22 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PMP22 5376 Q01453
PMP22 18858 P16646
PMP22 24660 P25094
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Top anti-PMP22 Antikörper auf antikoerper-online.de

Showing 10 out of 97 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PMP22 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IP, IHC, WB Immunohistochemical analysis of GAS3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of GAS3 expression in THP1 (A), MDAMB435 (B), mouse brain (C), mouse liver (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PMP22 Antibody  in Human normal Uterus cell line lysates (35ug/lane). This demonstrates the PMP22 antibody detected the PMP22 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from MDA-MB-435 cells, using PMP22 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PMP22 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert IHC (p), IHC, WB Staining of PMP22 (brown) in dorsal root ganglion and spinal roots in 20 week fetal spinal cord preparation from rhesus monkey. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PMP22 antibody ABIN213869 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PMP22 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$561.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis of extracts from HepG2, using GAS3 Antibody. Western blot analysis GAS3 using MDA-MB-435 whole cell lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated (ABIN726680) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat spinal cord labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details

Am meisten referenzierte anti-PMP22 Antikörper

  1. Human Monoclonal PMP22 Primary Antibody für IHC (p), IHC - ABIN258611 : Gregson, Zhang, Pritchard, Wang, Sanvito, Hayday, Hughes: Characterization of a monoclonal antibody specific for human peripheral myelin protein 22 and its use in immunohistochemical studies of the fetal and adult nervous system. in Journal of the peripheral nervous system : JPNS 2007 (PubMed)

Weitere Antikörper gegen PMP22 Interaktionspartner

Human Peripheral Myelin Protein 22 (PMP22) Interaktionspartner

  1. This study supported the notion that missense mutations in PMP22 give rise to a Charcot-Marie-Tooth Disease phenotype, possibly through a toxic gain-of-function mechanism.

  2. We identified that PMP22 not only acts as a marker for gastric CSCs but may also have an essential role in regulating the self-renewal and chemoresistance of gastric cancer. Our findings suggest that PMP22 has clinical value for the prognosis and treatment of chemoresistant gastric cancer

  3. In this Chinese Han population, the frequency of PMP22 gene duplication in those with CMT1 was slightly (50% vs. 70%-80%) less than in Western/Caucasian populations.

  4. PMP22 polymorphism is associated with tuberculosis.

  5. The studies implicating GAS3 protein family (EMP1, EMP2, EMP3 (zeige EMP3 Antikörper) and PMP22) in cancer pathogenesis as well as probe the structural similarities between the family members were highlighted.

  6. A Computational Approach to Identify a Potential Alternative Drug With Its Positive Impact Toward PMP22.

  7. Exome sequencing identified MFN2 (zeige MFN2 Antikörper) SNVs in two of the individuals. Neuropathy-associated CNV outside of the PMP22 locus is rare in Charcot-Marie-Tooth (CMT) disease . Nevertheless, there is potential clinical utility in testing for CNVs and exome sequencing in CMT cases negative for the CMT1A duplication.

  8. We discovered that Tead1 (zeige TEAD1 Antikörper) and co-activators Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) are required for Pmp22 expression, as well as for the expression of Egr2 (zeige EGR2 Antikörper) Tead1 (zeige TEAD1 Antikörper) directly binds Pmp22 and Egr2 (zeige EGR2 Antikörper) enhancers early in development and Tead1 (zeige TEAD1 Antikörper) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (zeige TEAD1 Antikörper) as a novel regulator of Pmp22 expression during development in concert with Sox10 (zeige SOX10 Antikörper) and Egr2 (zeige EGR2 Antikörper)

  9. This study demonstrated We show that blink (zeige TGFb Antikörper) reflex studies are reliable for identification of inherited demyelinating polyneuropathy (with pmp22 mutation) regardless of severity and can facilitate algorithmic decisions in genetic testing.

  10. Findings suggest that miR (zeige MLXIP Antikörper)-200bc/429 inhibit OS cells proliferation and invasion by targeting PMP22, and function as a tumor suppressor.

Mouse (Murine) Peripheral Myelin Protein 22 (PMP22) Interaktionspartner

  1. selective suppression of the Pmp22 mutant allele by non-viral delivery of siRNA alleviates the demyelinating neuropathic phenotypes of Charcot-Marie-Tooth disease in vivo

  2. We discovered that Tead1 (zeige TEAD1 Antikörper) and co-activators Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) are required for Pmp22 expression, as well as for the expression of Egr2 (zeige EGR2 Antikörper) Tead1 (zeige TEAD1 Antikörper) directly binds Pmp22 and Egr2 (zeige EGR2 Antikörper) enhancers early in development and Tead1 (zeige TEAD1 Antikörper) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (zeige TEAD1 Antikörper) as a novel regulator of Pmp22 expression during development in concert with Sox10 (zeige SOX10 Antikörper) and Egr2 (zeige EGR2 Antikörper)

  3. The basal lamina and PMP22 act in concert to contribute to a resilience and integrity of peripheral nerves at the single fibre level.

  4. A role was identified for PMP22 in the linkage of the actin cytoskeleton with the plasma membrane.

  5. This study demonistrated that Paranodal dysmyelination in peripheral nerves of Trembler mice.

  6. This study showed that a number of ongoing pathogenic mechanisms contribute to the progression of the neuropathy in C22 mice, which initiates with abnormal expression of PMP22.

  7. This study revealed a novel mechanism by which PMP22 deficiency affects nerve conduction not through removal of myelin, but through disruption of myelin junctions

  8. This study showed that mouse PMP22 is palmitoylated at C85 and mutating C85S abolishes PMP22 palmitoylation.

  9. Peripheral myelin protein 22 (PMP22) performs distinct actions on the formation, maturation, degeneration and regeneration of sciatic nerve myelin sheath.

  10. Egr2 (zeige EGR2 Antikörper) and Sox10 (zeige SOX10 Antikörper) activity are directly involved in mediating the developmental induction of Pmp22 expression through an intronic enhancer.

Zebrafish Peripheral Myelin Protein 22 (PMP22) Interaktionspartner

  1. The results of this study indicated that an adequate pmp22 transcription level is necessary for correct myelination of jawed vertebrates.

PMP22 Antigen-Profil

Protein Überblick

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit PMP22

  • peripheral myelin protein 22 (PMP22) Antikörper
  • peripheral myelin protein 22 (Pmp22) Antikörper
  • peripheral myelin protein 22a (pmp22a) Antikörper
  • peripheral myelin protein 22 S homeolog (pmp22.S) Antikörper
  • peripheral myelin protein 22 (pmp22) Antikörper
  • 22kDa Antikörper
  • CMT1A Antikörper
  • CMT1E Antikörper
  • DSS Antikörper
  • Gas-3 Antikörper
  • HMSNIA Antikörper
  • HNPP Antikörper
  • MGC69407 Antikörper
  • MGC80653 Antikörper
  • PMP22 Antikörper
  • Sp110 Antikörper
  • Tr Antikörper
  • trembler Antikörper
  • wu:fa04d03 Antikörper
  • wu:fa08d03 Antikörper

Bezeichner auf Proteinebene für PMP22

growth arrest-specific protein 3 , PMP-22 , peripheral myelin protein, 22 kDa , SAG , SR13 myelin protein , schwann cell membrane glycoprotein , peripheral myelin protein 22 , PAS positive glycoprotein , PASII

GENE ID SPEZIES
5376 Homo sapiens
18858 Mus musculus
24660 Rattus norvegicus
334817 Danio rerio
417327 Gallus gallus
446837 Xenopus laevis
479509 Canis lupus familiaris
534497 Bos taurus
594946 Xenopus (Silurana) tropicalis
693527 Macaca mulatta
744977 Pan troglodytes
100034146 Equus caballus
100172535 Pongo abelii
100302348 Ovis aries
100723804 Cavia porcellus
Ausgewählte Anbieter für anti-PMP22 (PMP22) Antikörper
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