anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antikörper

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. Zusätzlich bieten wir Ihnen Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Proteine (19) und Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PIN1 5300 Q13526
PIN1 298696  
PIN1 23988 Q9QUR7
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Top anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antikörper auf antikoerper-online.de

Showing 10 out of 232 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Ratte Ziege Unkonjugiert ELISA, WB ABIN185726 (0.2µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of NIH-3T3 cells, using Pin1 (Ab-1619) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of PIN1 (pS16) expression in HeLa insulin-treated (A), K562 (B), NIH3T3 (C), Raw264.7 insulin-treated (D), PC12 insulin-treated (E), C6 calyculin A-treated (F) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Human Kaninchen Unkonjugiert WB Anti- PIN1 Picoband antibody, Western blotting All lanes: Anti PIN1  at 0.5ug/ml Lane 1: Rat Lung Tissue Lysate at 50ug Lane 2: Mouse Lung Tissue Lysate at 50ug Lane 3: NRK Whole Cell Lysate at 40ug Lane 4: A549 Whole Cell Lysate at 40ug Lane 5: 293T Whole Cell Lysate at 40ug Lane 6: MCF-7 Whole Cell Lysate at 40ug Predicted bind size: 19KD Observed bind size: 19KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with insulin 0.01U/ml 15', using Pin1 (Phospho-Ser16) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart, using Pin1 (Phospho-Ser16) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of PIN1 Antibody (Center) (ABIN652906) in HL-60 cell line lysates (35 µg/lane). PIN1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PIN1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6267639 at 1/200 staining human lymph node tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of Pin1 phosphorylation expression in Insulin treated COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$389.00
Details
Human Maus Unkonjugiert SDS, ELISA, WB Flow Cytometry: Pin1 Antibody (3G8) [NBP1-22956] - Analysis of Pin1 in Jurkat cell line, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line). Western Blot: Pin1 Antibody (3G8) [NBP1-22956] Cell lysates of 293T, HeLa and Jurkat (each 50ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Pin1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Anmelden zum Anzeigen 12 bis 15 Tage
$415.44
Details

Am meisten referenzierte anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antikörper

  1. Human Polyclonal PIN1 Primary Antibody für ICC, IF - ABIN438364 : Islam, Bae, Yoon, Woo, Baek, Kim, Uchida, Ryoo: Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP. in Journal of cellular physiology 2014 (PubMed)
    Show all 2 Pubmed References

  2. Rat (Rattus) Polyclonal PIN1 Primary Antibody für ELISA, WB - ABIN251689 : Pastorino, Sun, Lu, Zhou, Balastik, Finn, Wulf, Lim, Li, Li, Xia, Nicholson, Lu: The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. in Nature 2006 (PubMed)

Weitere Antikörper gegen Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Interaktionspartner

Human Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 plays a role as a vital modulator of vascular smooth muscle cell senescence

  2. PIN1 rs2233682 A allele might be related with a decreased risk of hepatitis B virus-related liver cirrhosis in a Guangxi population.

  3. Downregulation of miR (zeige MLXIP Antikörper)-370 in esophageal squamous cell carcinoma is associated with cancer progression and promotes cancer cell proliferation via upregulating PIN1, which might be a potential therapeutic target and adverse prognostic factor in the clinic.

  4. Study investigated the allosteric mechanism of full-length Pin1 using several microsecond-long molecular dynamics simulations; show that binding of the substrate to the WW domain (zeige DRP2 Antikörper) is directly coupled to the dynamics of the catalytic domain, causing rearrangement of the residue-residue contact dynamics from the WW domain (zeige DRP2 Antikörper) to the catalytic domain.

  5. Pin1 is a fast-acting enzyme which may be utilised by cells to protect the phosphorylation state of Tissue Factor (zeige F3 Antikörper) (TF) in activated cells prolonging TF activity and release, and therefore ensuring adequate haemostasis.

  6. statistically significant correlation didn't exist between serum level of PIN1 and the systolic and diastolic blood pressure, between serum level of eNOS (zeige NOS3 Antikörper) and diastolic blood pressure in the norm tension Alzheimer's disease patients, between serum levels of PIN1, eNOS (zeige NOS3 Antikörper) and systolic blood pressure, and between serum eNOS (zeige NOS3 Antikörper) and systolic and diastolic blood pressure in the patients with hypertension.

  7. Studies results suggest that loss of peptidyl-prolyl isomerase (Pin1) activity could lead to the loss of synaptic plasticity in the development of Alzheimer disease.

  8. Pin1 induces the ADP-induced migration of human dental pulp cells through P2Y1 (zeige P2RY1 Antikörper) stabilization.

  9. In this study, we were aimed to investigate whether the cross talk between pin1 and Notch1 (zeige NOTCH1 Antikörper) has a role in this event. Our results indicated that the expression level of Pin1 in resistant SKBR3 cells increased by about twofold relative to sensitive SKBR3 cells. Besides, Pin1 inhibition via juglone reduced the extent of proliferation, colony formation and migration capacity of resistant SKBR3 cells

  10. Parallel folding pathways of PIN1 Fip35 WW domain (zeige DRP2 Antikörper) have been explained by infrared spectra and their computer simulations.

Xenopus laevis Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 is an essential factor regulating CPEB degradation

  2. Pin1 binding is required for the inactivation of XeWee1B at M phase, presumably causing isomerization of the phospho-TP motif and thereby impairing the function of the Wee (zeige WEE1 Antikörper)-box

Cow (Bovine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. The data provide the first evidence that Pin 1 expression in the granulosa cells but not the theca cells changes during follicular development, and that FSH (zeige BRD2 Antikörper) stimulate the expression of the Pin 1 gene.

Mouse (Murine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 serves as a modulator of SERCA2a (zeige ATP2A2 Antikörper) and Na(2+)/Ca(2 (zeige CA2 Antikörper)+) exchanger 1 Ca(2 (zeige CA2 Antikörper)+) handling proteins, with loss of function resulting in impaired cardiomyocyte relaxation.

  2. These results suggest that Pin1 promotes the progression of the mitotic cell cycle of SSC (zeige CYP11A1 Antikörper) in steady-state, which is required for the sperm production from SSCs.

  3. Pin1 silencing in lymphomas retarded disease progression in mice, making Pin1 an attractive therapeutic target in Myc (zeige MYC Antikörper)-driven tumors.

  4. Pin1 enhances adipocyte differentiation by regulating the function of PPARgamma (zeige PPARG Antikörper).

  5. Pin1 serves as a positive regulatory molecule of proplatelet formation of megakaryocytes by enhancing the function of phosphorylated tau.

  6. Direct delivery of recombinant Pin1 via fibroin nanoparticle encapsulated cationic lipid complex successfully rescued osteoblast differentiation of pin-1 deficient cells.

  7. Pin1 plays important role in the cell cycle progression and increase oval cells proliferation which may be crucial in chronic liver injury.

  8. in vivo functional analyses of Pin1 in the GFAP (zeige GFAP Antikörper)-tTA;TRE (zeige TREH Antikörper)-SmoA1 mouse model of Hedgehog (zeige SHH Antikörper)-driven medulloblastoma demonstrate that the loss of Pin1 impairs tumor development and dramatically increases survival.

  9. Data, including data from studies conducted with knockout mice, suggest that Pin1 (prolyl isomerase 1) expression in pancreatic beta-cells is markedly elevated in obesity from diet high in fat/sucrose; Pin1 appears to be involved in proliferation of beta-cells and in regulation of secretion of insulin (zeige INS Antikörper); Pin1 interacts with Sik2 (salt-inducible kinase 2 (zeige SIK2 Antikörper)) to regulate calcium signaling.

  10. Pin1 knockout in lupus-prone MRL lpr (zeige FAS Antikörper) mice prevents expression of lupus phenotype.

Zebrafish Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. analysis of Pin1 overexpression showed alterations on zebrafish development and the presence of p53 (zeige TP53 Antikörper)-dependent apoptosis. Collectively, our results suggest that specific mechanisms are operated in different cell types to regulate Pin1 function

Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antigen-Profil

Protein Überblick

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit PIN1

  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (Pin1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog (pin1.S) Antikörper
  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog (pin1.L) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (ppiD) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PITG_11123) Antikörper
  • peptidyl-prolyl cis-trans isomerase Pin1 (pin1) Antikörper
  • peptidyl-prolyl cis-trans isomerase Pin1 (LOC103419188) Antikörper
  • 0610025L01Rik Antikörper
  • D9Bwg1161e Antikörper
  • dod Antikörper
  • MdPin1 Antikörper
  • Pin1 Antikörper
  • pin1a Antikörper
  • pin1b Antikörper
  • PPIase pin1 Antikörper
  • ubl5 Antikörper
  • zgc:73206 Antikörper

Bezeichner auf Proteinebene für PIN1

PPIase Pin1 , peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 , protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 , rotamase Pin1 , protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1 , prolyl isomerase Pin1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 a , peptidyl-prolyl cis-trans isomerase Pin1 , prolyl isomerase Pin1 b , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 b , Pin1-type peptidyl-prolyl cis/trans isomerase , Rotamase Pin1

GENE ID SPEZIES
5300 Homo sapiens
298696 Rattus norvegicus
484963 Canis lupus familiaris
493472 Xenopus (Silurana) tropicalis
503670 Xenopus laevis
535470 Bos taurus
711095 Macaca mulatta
745021 Pan troglodytes
23988 Mus musculus
399385 Xenopus laevis
5807350 Sorangium cellulosum So ce56
9476290 Phytophthora infestans T30-4
100512827 Sus scrofa
100726337 Cavia porcellus
393721 Danio rerio
2539218 Schizosaccharomyces pombe 972h-
103419188 Malus domestica
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