anti-Peptidylglycine alpha-Amidating Monooxygenase (PAM) Antikörper

PAM encodes a multifunctional protein. Zusätzlich bieten wir Ihnen PAM Kits (10) und PAM Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PAM 5066 P19021
PAM 18484 P97467
PAM 25508 P14925
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Top anti-PAM Antikörper auf antikoerper-online.de

Showing 10 out of 28 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PAM Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: PAM Sample Type: Stomach Tumor lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN238682 (1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Recombinant PAM, Human. DAB staining on IHC-P; Samples: Human Kidney Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: PAM Antibody [NBP2-34075] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunohistochemistry-Paraffin: PAM Antibody [NBP2-34075] - Immunohistochemical staining of human small intestine shows strong positivity in a subset of neuroendocrine cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB PAM antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details

PAM Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen PAM Interaktionspartner

Fruit Fly (Drosophila melanogaster) Peptidylglycine alpha-Amidating Monooxygenase (PAM) Interaktionspartner

Human Peptidylglycine alpha-Amidating Monooxygenase (PAM) Interaktionspartner

  1. The ancient ability of PAM to localize to ciliary membranes, which release bioactive ectosomes, may be related to its ability to accumulate in intralumenal vesicles and exosomes

  2. PAM expression is increased in the secretory pathway of differentiated neurons.

  3. Oxygen Sensitivity of the Peptidylglycine alpha-Amidating Monooxygenase (PAM) in Neuroendocrine Cells

  4. Two missense variants in PAM, encoding p.Asp563Gly (frequency of 4.98%) and p.Ser539Trp (frequency of 0.65%), confer moderately higher risk of type 2 diabetes (OR = 1.23, P = 3.9 x 10(-10) and OR = 1.47, P = 1.7 x 10(-5), respectively)

  5. Detail the production of the catalytic core of human peptidylglycine alpha-hydroxylating monooxygenase (hPHMcc) in Escherichia coli possessing a N-terminal fusion to thioredoxin (Trx (zeige TXN Antikörper)).

  6. Data indicate that catalytic inactivation of PHM caused by pH changes is accompanied by structural change between two states of the protein involving strong Cu-S interaction that does not involve M314.

  7. nuclear retention of PAM mRNA is lost upon expressing the La proteins that lack a conserved nuclear retention element, suggesting a direct association between PAM mRNA and La protein in vivo

Mouse (Murine) Peptidylglycine alpha-Amidating Monooxygenase (PAM) Interaktionspartner

  1. Oxygen Sensitivity of the Peptidylglycine alpha-Amidating Monooxygenase (PAM) in Neuroendocrine Cells

  2. Disruption of AP-1 (zeige JUN Antikörper)-dependent late endosomal trafficking diminishes the ability of PAM to retain copper and produce amidated peptides.

  3. deficits in PAM reversibly affect copper homeostasis, with behavioral and physiological consequences

  4. Reduced amygdalar expression of Atox-1 (zeige ATOX1 Antikörper) and Atp7a (zeige ATP7A Antikörper) in PAM heterozygous mice may lead to reduced synaptic Cu levels, contributing to the behavioral and neurochemical alterations seen in these mice.

  5. While glycine-extended reaction intermediates accumulated in the PAM(+/-) mice and reflected dietary copper availability, amidated products were far more prevalent under the conditions examined.

  6. Although the copper-dependent mechanisms through which the endocytic trafficking of PAM alters gene expression have not been elucidated in this review, the cytosolic fragment of PAM identified in pituitary and atrial nuclei is likely to play a key role.

  7. Cleavage of PAM releases a soluble CD fragment that localizes to the nucleus. Localization of PAM-CD to the nucleus was decreased when PAM-CD with phosphomimetic mutations was examined and when active Uhmk1 (zeige UHMK1 Antikörper) was simultaneously overexpressed.

  8. Altered copper homeostasis in PAM(+/-) mice suggested a role for PAM in the cell type specific regulation of copper metabolism.

  9. In 12-day-old (P12 (zeige CDK2AP1 Antikörper)) mouse pups derived from dams that began Cu deficiency on day 7 of gestation, there was a parallel reduction in brain PAM activity and protein of 40-50%.

  10. expression analysis of PHM in rats and in mouse cells

Cow (Bovine) Peptidylglycine alpha-Amidating Monooxygenase (PAM) Interaktionspartner

PAM Antigen-Profil

Protein Überblick

This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.

Genbezeichner und Symbole assoziert mit PAM

  • Peptidylglycine-alpha-hydroxylating monooxygenase (Phm) Antikörper
  • peptidylglycine alpha-amidating monooxygenase (PAM) Antikörper
  • peptidylglycine alpha-amidating monooxygenase (CHLREDRAFT_150435) Antikörper
  • peptidylglycine alpha-amidating monooxygenase (sce7070) Antikörper
  • peptidylglycine alpha-amidating monooxygenase (pam) Antikörper
  • peptidylglycine alpha-amidating monooxygenase (Pam) Antikörper
  • CG3832 Antikörper
  • Dmel\\CG3832 Antikörper
  • dPHM Antikörper
  • PAL Antikörper
  • phm Antikörper

Bezeichner auf Proteinebene für PAM

CG3832-PA , CG3832-PB , Phm-PA , Phm-PB , peptidyl gycine alpha hydroxylating monooxygenase , peptidylglycine alpha-hydroxylating monooxygenase , peptidylglycine-alpha-hydroxylating monooxygenase , peptidylglycine alpha-amidating monooxygenase , peptidyl-glycine alpha-amidating monooxygenase , peptidyl-glycine alpha-amidating monooxygenase-like , pancreatic peptidylglycine alpha-amidating monooxygenase , peptidyl alpha-amidating enzyme , peptidyl-alpha-hydroxyglycine alpha-amidating lyase , peptidylamidoglycolate lyase , peptidylglycine 2-hydroxylase , PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PRECURSOR (PAM)

GENE ID SPEZIES
37823 Drosophila melanogaster
427274 Gallus gallus
461974 Pan troglodytes
479145 Canis lupus familiaris
707733 Macaca mulatta
791244 Equus caballus
5723115 Chlamydomonas reinhardtii
5811519 Sorangium cellulosum So ce56
100030601 Monodelphis domestica
100170159 Xenopus (Silurana) tropicalis
100352005 Oryctolagus cuniculus
100396001 Callithrix jacchus
100449730 Pongo abelii
100484534 Ailuropoda melanoleuca
100526040 Sus scrofa
100562563 Anolis carolinensis
100603954 Nomascus leucogenys
5066 Homo sapiens
18484 Mus musculus
25508 Rattus norvegicus
280890 Bos taurus
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