Pannexin 2 (PANX2) ELISA Kits

The protein encoded by PANX2 belongs to the innexin family. Zusätzlich bieten wir Ihnen Pannexin 2 Antikörper (120) und Pannexin 2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human PANX2 PANX2 56666 Q96RD6
Anti-Maus PANX2 PANX2 406218 Q6IMP4
Anti-Ratte PANX2 PANX2 362979 P60571
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Weitere ELISA Kits für Pannexin 2 Interaktionspartner

Human Pannexin 2 (PANX2) Interaktionspartner

  1. The pannexin 2 (Panx2) N86Q mutant is glycosylation-deficient and tends to aggregate in the endoplasmic reticulum (ER)reducing its cell surface trafficking but it can still interact with pannexin 1 (Panx1).

  2. All three pannexins Panx1, Panx2, and Panx3 mRNAs were expressed in all of the analyzed undifferentiated stem cell lines.

  3. Panx2 mRNA and protein levels were only upregulated in focal cortical dysplasia type IIb lesions of intractable epilepsy patients and characteristically expressed on SOX2-positive multipotential balloon cells.

  4. Panx2 is an important regulator of the insulin secretory capacity and apoptosis in pancreatic beta-cells.

  5. The results of this study do not support a major contribution of PANX1-3 to disease risk of schizophrenia according to DSM-5.

  6. There is dense expression of Panx2 in the enteric nervous system. The substantial increase in Panx2 mRNA in ulcerative colitis (UC) muscle but not protein suggests that the Panx2 translation process may be disrupted in UC.

  7. Data suggest that both up-regulation and down-regulation of expression of pannexins (PANX1, PANX2, PANX3) are associated with disease onset and/or progression; examples include neoplasms, multiple sclerosis, migraine, and hypertension. [REVIEW]

  8. Panx1 and Panx2 expression was detected in the temporal lobe cortex of patients with temporal lobe epilepsy and in the control tissues.

  9. Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other

  10. These data do not suggest that Panx2 or Cx36 could increase the risk of schizophrenia in the Japanese population.

  11. Pannexin2 is a tumor suppressor gene in C6 glioma cells.

  12. According to brain cancer gene expression database REMBRANDT, PANX2 expression levels can predict post diagnosis survival for patients with glial tumors.

Mouse (Murine) Pannexin 2 (PANX2) Interaktionspartner

  1. Panx2 is an important regulator of the insulin secretory capacity and apoptosis in pancreatic beta-cells.

  2. It used overlap-extension cloning to create the first chimeric Panx, consisting of Panx2 with the Panx1 C-terminus (Panx2(Panx1CT)), to determine whether the Panx1 C-terminus influences the trafficking of Panx2.

  3. ). Pannexin double-knockout mice (Px1(-/-) Px2(-/-)) were less impaired in parameters such as exploration, anxiety, sensorimotor function and behavioral symmetry.

  4. In situ hybridization revealed that mRNAs for Panx1 and Panx2 were both expressed in the olfactory epithelium and olfactory bulb.

  5. Px1 and Px2 underlie channel function in neurons and contribute to ischemic brain damage

  6. Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment

  7. Panx2 strongly interacts with the core and high-mannose species of Panx1 but not with Panx3. The combination of Panx1 & Panx2 results in compromised channel function.

  8. Results reveal a widespread and similar mRNA distribution for both pannexin 1 and 2, but indicate that they are inversely regulated during the development of the rat brain.

  9. Panx1 and Panx2 are abundantly expressed in the retina, and may therefore contribute to the electrical and metabolic coupling, or to signaling between retinal neurons

  10. Despite similarity in detergent solubility of pannexins and connexins, the lack of spatial co-localization in the lens membranes suggested a distinct, non-redundant to connexin function for these proteins in the lens cell membrane.

  11. Data show that Panx2 is expressed in the spiral and Scarpa's ganglion neurons.

  12. Results show that pannexins 1, 2, and 3 are abundantly expressed in the mouse and rat cochlea and demonstrate distinct cellular distributions.

Pannexin 2 (PANX2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Pannexin 2 (PANX2) ELISA Kits

  • pannexin 2 (PANX2) Antikörper
  • pannexin 2 (LOC100533356) Antikörper
  • pannexin 2 (panx2) Antikörper
  • pannexin 2 (Panx2) Antikörper
  • hPANX2 Antikörper
  • PANX2 Antikörper
  • PX2 Antikörper
  • si:ch211-192n14.2 Antikörper

Bezeichner auf Proteinebene für Pannexin 2 (PANX2) ELISA Kits

pannexin 2 , pannexin-2 , pannexin-2-like

470248 Pan troglodytes
539070 Bos taurus
100519315 Sus scrofa
100533356 Aplysia californica
100579918 Nomascus leucogenys
557828 Danio rerio
426934 Gallus gallus
56666 Homo sapiens
481195 Canis lupus familiaris
406218 Mus musculus
362979 Rattus norvegicus
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