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Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Zusätzlich bieten wir Ihnen PRPF40A Proteine (3) und und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal PRPF40A Primary Antibody für IF, WB - ABIN527604
Jiang, Che, Yuan, Xie, Yan, Hu: Interaction with polyglutamine-expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA). in The Journal of biological chemistry 2011
our data revealed that COL1A1 (zeige COL1A1 Antikörper), UCP2 (zeige UCP2 Antikörper), and PRPF40A are novel players implicated in the complex network of hypoxia response in non-small cell lung cancer
Multidisciplinary approach showed that HsPrp40Ap interacts with centrin (zeige CETN1 Antikörper) in vitro, supporting a coupled functional role for these proteins in pre-mRNA splicing.
Study of native domain FF3-71 from human HYPA/FBP11 and the truncated version FF3-60 with C-terminal helix being deleted by molecular dynamics simulations.
Interaction with polyglutamine-expanded huntingtin (zeige HTT Antikörper) alters cellular distribution and RNA processing of huntingtin (zeige HTT Antikörper) yeast two-hybrid protein A (zeige GPR153 Antikörper) (HYPA).
Data describe the structure of an FF domain from HYPA/FBP11, which differs from those of other phosphopeptide-binding domains and represents a novel phosphopeptide-binding fold.
Results suggest an essential role of WW/FF domain-containing factors such as FBP11 and CA150 (zeige TCERG1 Antikörper) in pre-mRNA splicing that likely occurs in concert with transcription in vivo.
NAKAP (zeige AKAP8L Antikörper)-HypA scaffold is a potential nuclear docking site for huntingtin (zeige HTT Antikörper) protein and may contribute to the nuclear accumulation of huntingtin (zeige HTT Antikörper) observed in HD.
FBP11 binding mechanism underlies the molecular pathology of severe neurological disorders, e.g., Rett syndrome and Huntington disease (zeige HTT Antikörper).
FBP11 regulates localization of N-WASP, thus negatively regulating the function of N-WASP in the cytoplasm
Results suggest an essential role of WW/FF domain-containing factors such as FBP11 (zeige FMNL3 Antikörper) and CA150 (zeige TCERG1 Antikörper) in pre-mRNA splicing that likely occurs in concert with transcription in vivo.
Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.
formin binding protein 3
, Fas-ligand associated factor 1
, Huntingtin-interacting protein A
, NY-REN-6 antigen
, fas ligand-associated factor 1
, formin-binding protein 11
, huntingtin yeast partner A
, huntingtin-interacting protein 10
, pre-mRNA-processing factor 40 homolog A
, renal carcinoma antigen NY-REN-6
, pre-mRNA processing factor 40 homolog A
, formin binding protein 11
, formin-binding protein 3