anti-PR Domain Containing 14 (PRDM14) Antikörper

PRDM14 encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. Zusätzlich bieten wir Ihnen PRDM14 Proteine (5) und PRDM14 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PRDM14 63978 Q9GZV8
PRDM14 383491 E9Q3T6
PRDM14 100365184  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-PRDM14 Antikörper auf antikoerper-online.de

Showing 10 out of 94 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Human Lung WB Suggested Anti-PRDM14 Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western blot analysis of PRDM14 polyclonal antibody (ABIN388018) in A549 cell lysate. PRDM14 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ChIP, IF, IP, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, WB   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Maus Unkonjugiert ICC, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert ChIP, IC, IF, IP, IHC, WB Immunofluorescent analysis of PRDM14 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Immunohistochemical analysis of PRDM14 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Rind (Kuh) Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$373.75
Details

PRDM14 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, , ,
,
, , , , , , , , , , , , , , , ,
Mouse (Murine) ,
,

Rat (Rattus) ,
,

Am meisten referenzierte anti-PRDM14 Antikörper

  1. Human Polyclonal PRDM14 Primary Antibody für IF, IHC (p) - ABIN388018 : Jiang, Huang: The yin-yang of PR-domain family genes in tumorigenesis. in Histology and histopathology 2000 (PubMed)
    Show all 5 Pubmed References

  2. Cow (Bovine) Polyclonal PRDM14 Primary Antibody für ELISA - ABIN4239519 : Chia, Chan, Feng, Lu, Orlov, Moreau, Kumar, Yang, Jiang, Lau, Huss, Soh, Kraus, Li, Lufkin, Lim, Clarke, Bard, Ng: A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. in Nature 2010 (PubMed)

Weitere Antikörper gegen PRDM14 Interaktionspartner

Human PR Domain Containing 14 (PRDM14) Interaktionspartner

  1. Results identified GRP78 (zeige HSPA5 Antikörper) and HSP90a (zeige HSP90AA1 Antikörper) as binding partners of PRDM14 in triple-negative breast cancer cells, and all participate in cancer regulation. The interactions were direct and required the C-terminal region including the zinc finger motifs of PRDM14.

  2. miR (zeige MLXIP Antikörper)-424-->cdc42 (zeige CDC42 Antikörper)-->prdm14 axis as a key molecular signalling cascade that might influence breast cancer progression in diabetic patients through hyperactivation of cancer stem cells.

  3. High expression of PRDM14 is associated with liver metastasis in pancreatic cancer.

  4. PRDM14 role in cell proliferation and cell migration

  5. PRDM14 bears a single PR domain and six tandemly repeated zinc fi ngers, which is involved in the process of the deacetylation and methylation of the histone, and is involved in the formation of tumor . [review]

  6. In response to cytokines, pluripotent stem cells differentiate first into a heterogeneous mesoderm-like cell population and then into Primordial Germ cell-Like Cells, which exhibit minimal PRDM14 expression.

  7. The contribution of methylation-mediated gene silencing of PRDM14 to apoptosis evasion in HPV-positive cancer cells offers novel therapeutic options for HPV-induced cancers.

  8. PRDM14 associated with cell differentiation in NSCLC.

  9. Study reveals a repressive role of PRDM14 in the maintenance and induction of pluripotency and identifies PRDM14 as a new regulator of PRC2.

  10. The high expression of PRDM14 in non-small cell lung cancer is associated with differentiation and histological type.

Mouse (Murine) PR Domain Containing 14 (PRDM14) Interaktionspartner

  1. PRDM14 recruited OCT3/4 (zeige POU5F1 Antikörper) to the enhancer regions of naive pluripotency genes via TET-base excision repair-mediated demethylation.

  2. JARID2 (zeige JARID2 Antikörper) physically interacts with ESRRB (zeige ESRRB Antikörper), SALL4A (zeige SALL4 Antikörper), and PRDM14

  3. This repressive function is mediated through an ETO (zeige RUNX1T1 Antikörper)-family co-repressor Mtgr1 (zeige CBFA2T2 Antikörper), which tightly binds to the pre-SET/SET domains of Prdm14 and co-occupies its genomic targets in mouse embryonic stem cells.

  4. the H3K27-specific demethylase (zeige MBD2 Antikörper) Utx (zeige KDM6A Antikörper) regulates the expression of the master regulators for XCI and XCR: Prdm14, Tsix, and Xist.

  5. Both TET1 (zeige TET1 Antikörper) and TET2 (zeige TET2 Antikörper) are required for the repression of embryonic stem cells differentiation by PRDM14.

  6. Upregulation of Prdm14 results in a highly homogeneous population of authentic pluripotent colonies and prevents the abnormal silencing of the Dlk1 (zeige DLK1 Antikörper)-Dio3 (zeige DIO3 Antikörper) locus.

  7. PRDM14 is heterogeneously expressed in 4-cell-stage embryos. Forced expression of PRDM14 at the 2-cell stage leads to increased H3R26me2 and can induce a pluripotent ICM fate.

  8. PRDM14-induced leukemic cells contain high levels of activated NOTCH1 (zeige NOTCH1 Antikörper) and downstream NOTCH1 (zeige NOTCH1 Antikörper) targets, including MYC (zeige MYC Antikörper) and HES1, and are sensitive to pharmacological inhibition of NOTCH1 (zeige NOTCH1 Antikörper) with the gamma-secretase inhibitor DAPT

  9. PRDM14 physically interacts with TET1 (zeige TET1 Antikörper) and TET2 (zeige TET2 Antikörper) and enhances the recruitment of TET1 (zeige TET1 Antikörper) and TET2 (zeige TET2 Antikörper) at target loci. Knockdown of TET1 (zeige TET1 Antikörper) and TET2 (zeige TET2 Antikörper) impaired transcriptional regulation and DNA demethylation by PRDM14.

  10. Tsix and PRDM14 directly link X-chromosome reactivation to stem cell pluripotency.

Zebrafish PR Domain Containing 14 (PRDM14) Interaktionspartner

  1. Prdm14 regulates Caudal (zeige CAD Antikörper) primary axon outgrowth through activation of islet2 expression.

PRDM14 Antigen-Profil

Protein Überblick

This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer.

Genbezeichner und Symbole assoziert mit PRDM14

  • PR/SET domain 14 (PRDM14) Antikörper
  • PR domain containing 14 (Prdm14) Antikörper
  • PR domain containing 14 (PRDM14) Antikörper
  • PR domain containing 14 (prdm14) Antikörper
  • PR/SET domain 14 (Prdm14) Antikörper
  • fc16b12 Antikörper
  • PFM11 Antikörper
  • PRDM14 Antikörper
  • prmd14 Antikörper
  • wu:fc16b12 Antikörper

Bezeichner auf Proteinebene für PRDM14

PR domain zinc finger protein 14 , PR domain-containing protein 14 , PR domain containing 14 , PR domain zinc finger protein 14-like , PR domain 14 , PR domain containing 14-like

GENE ID SPEZIES
63978 Homo sapiens
383491 Mus musculus
428362 Gallus gallus
464224 Pan troglodytes
486988 Canis lupus familiaris
563151 Danio rerio
693324 Macaca mulatta
100140032 Bos taurus
100347807 Oryctolagus cuniculus
100411718 Callithrix jacchus
100457355 Pongo abelii
100469835 Ailuropoda melanoleuca
100519142 Sus scrofa
100028758 Monodelphis domestica
100062473 Equus caballus
100584766 Nomascus leucogenys
100365184 Rattus norvegicus
100735710 Cavia porcellus
Ausgewählte Anbieter für anti-PRDM14 (PRDM14) Antikörper
Haben Sie etwas anderes gesucht?