PHD Finger Protein 2 Proteine (PHF2)

PHF2 encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. Zusätzlich bieten wir Ihnen PHF2 Antikörper (38) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PHF2 5253 O75151
PHF2 18676 Q9WTU0
Ratte PHF2 PHF2 306814  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$12,127.90
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$12,127.90
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

PHF2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu PHD Finger Protein 2 (PHF2) Interaktionspartnern

Human PHD Finger Protein 2 (PHF2) Interaktionspartner

  1. Frameshift mutations of PHF2 (zeige PHF1 Proteine) may play a role in tumorigenesis through its TSG (zeige TWSG1 Proteine) inactivation in CRC (zeige CALR Proteine) and GC.

  2. PHF2 (zeige PHF1 Proteine) acts as a tumor suppressor in association with p53 (zeige TP53 Proteine) in cancer development and ensures p53 (zeige TP53 Proteine)-mediated cell death in response to chemotherapy.

  3. PHF2 (zeige PHF1 Proteine) is likely to repress rDNA transcription by competing with PHF8 (zeige PHF8 Proteine) for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1 (zeige SUV39H1 Proteine).

  4. JARID1B (zeige KDM5B Proteine) and PHF2 (zeige PHF1 Proteine) are overexpressed in esophageal squamous cell carcinoma (ESCC) and they may play crucial roles in the course of ESCC initiation and/or progression

  5. the crystal structures of PHF2 (zeige PHF1 Proteine) Jumonji (zeige JARID2 Proteine) domain in the absence and presence of additional exogenous metal ions were determined.

  6. Differential association of alterations in FANCC (zeige FANCC Proteine) and PTCH1 (zeige PTCH1 Proteine) with that of PHF2 (zeige PHF1 Proteine), XPA (zeige XPA Proteine) and two breast cancer susceptibility genes (BRCA1/BRCA2 (zeige BRCA2 Proteine)) in the two age groups suggests differences in their molecular pathogenesis.

Mouse (Murine) PHD Finger Protein 2 (PHF2) Interaktionspartner

  1. these results demonstrate that PHF2 histone demethylase (zeige MBD2 Proteine) controls adipogenic gene expression during differentiation.

  2. PHF2 enhances osteoblast differentiation by demethylating Runx2 (zeige RUNX2 Proteine), while suppressor of variegation 3-9 homolog 1 (SUV39H1 (zeige SUV39H1 Proteine)) inhibits bone formation by methylating it.

  3. Arid5b (zeige ARID5B Proteine) recruits Phf2 to the promoter region of Sox9 (zeige SOX9 Proteine) target genes and stimulates H3K9me2 demethylation of these genes.

  4. Data from PHF2 knockout mice suggest that PHF2 plays roles in both adipogenesis and neonatal growth/weight gain; PHF2 interacts with promoter region of CEBPA (CCAAT-enhancer binding protein alpha (zeige CEBPA Proteine)) gene and demethylates histones in chromatin.

  5. histone H3K4 trimethylation by a homeodomain of PHF2 modulates histone demethylation

PHF2 Protein Überblick

Protein Überblick

This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure.

Genbezeichner und Symbole assoziert mit PHD Finger Protein 2 Proteine (PHF2)

  • PHD finger protein 2 (PHF2)
  • PHD finger protein 2 (Phf2)
  • PHD finger protein 2 (phf2)
  • CENP-35 Protein
  • GRC5 Protein
  • im:4200679 Protein
  • JHDM1E Protein
  • phf8 Protein
  • wu:fa14c10 Protein

Bezeichner auf Proteinebene für PHD Finger Protein 2 Proteine (PHF2)

centromere protein 35 , jumonji C domain-containing histone demethylase 1E , lysine-specific demethylase PHF2 , PHD finger protein 8 , lysine-specific demethylase phf2 , PHD finger protein 2

GENE ID SPEZIES
5253 Homo sapiens
18676 Mus musculus
503778 Danio rerio
415981 Gallus gallus
306814 Rattus norvegicus
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