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catalyzes conversion of prostaglandin H2 to prostaglandin D2, a major prostaglandin that mediates sleep, body temperature, hormone release, and odor responses. Zusätzlich bieten wir Ihnen PGD Synthetase Antikörper (12) und PGD Synthetase Proteine (1) und viele weitere Produktgruppen zu diesem Protein an.
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These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS (zeige PTGDS ELISA Kits) expression and subsequent PGD2 (zeige PTGDS ELISA Kits) production in the tumor endothelial cells (ECs). This PGD2 (zeige PTGDS ELISA Kits) acts as a negative regulator of the tumorigenic changes in tumor ECs.
Exposure of macrophages to cyclooxygenase (COX-2 (zeige COX2 ELISA Kits)) inhibitors RhoA (zeige RHOA ELISA Kits) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 (zeige PTGDS ELISA Kits) receptors or the hepatocyte growth factor (HGF (zeige HGF ELISA Kits)) receptor c-Met (PHA-665752), reversed EMT (zeige ITK ELISA Kits) inhibition by the conditioned medium
Ptgds is targeted and repressed by the CUL4B/PRC2 complex.
Thermodynamic and nuclear magnetic resonance analyses demonstrated that L-PGDS binds to nicotinamide coenzymes, including NADPH, NADP(+), and NADH.
Prostaglandin D2 synthase is a novel MR target (zeige PTGDS ELISA Kits) gene in adipocytes.
When prostaglandin D2 synthase (zeige PTGDS ELISA Kits) is upregulated it participates in the regulation of peripheral nervous system myelination.
expression of L-PGDS (zeige PTGDS ELISA Kits) in mouse lungs decreased neutrophilic infiltration, ameliorating lung inflammation in mice.
Silencing of PTGDS also alleviated H-rev107-mediated suppression of cell migration and invasion
In this report, we show for the first time that alteration of the PTGDS (zeige PTGDS ELISA Kits)-governed PGD2 (zeige PTGDS ELISA Kits) pathway disturbs testicular migration in mice.
Data indicate a PLA2G3 (zeige PLA2G3 ELISA Kits)-lipocalin (zeige APOD ELISA Kits)-type PGD2 synthase (L-PGDS)-PGD2 (zeige PTGDS ELISA Kits) receptor DP1 (zeige PTGDR ELISA Kits) loop that drives mast cell maturation.
High lipocalin-type prostaglandin D synthase (zeige PTGDS ELISA Kits) expression is associated with Spontaneous intracranial hypotension.
Thus, our results suggest decreased NK cell-mediated eosinophil regulation, possibly through an increased level of PGD2, as a previously unrecognized link between PG dysregulation and eosinophilic inflammation in CRS.
Serum levels of beta trace protein and beta 2 microglobulin (zeige B2M ELISA Kits) can be used to predict residual kidney function in hemodialysis patients.
BTP and B2M levels are less affected than serum by amputation, and should be considered for future study of GFR estimation
Hematopoietic prostaglandin D synthase (zeige HPGDS ELISA Kits) defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function
levels of L-PGDS (zeige PTGDS ELISA Kits) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.
PTGDS (zeige PTGDS ELISA Kits) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.
Expression of MR and prostaglandin D2 synthase (zeige PTGDS ELISA Kits) is strongly correlated in adipose tissues from obese patients.
These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase (zeige PTGDS ELISA Kits) distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
, glutathione-independent PGD synthase
, glutathione-independent PGD synthetase
, lipocalin-type prostaglandin-D synthase
, prostaglandin D2 synthase (21 kDa, brain)
, prostaglandin-D2 synthase
, prostaglandin-H2 D-isomerase
, Prostaglandin D synthase
, beta-trace protein
, lipocalin-type prostaglandin D synthase
, prostaglandin D synthase