PDZ and LIM Domain 5 Proteine (PDLIM5)

PDLIM5 encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. Zusätzlich bieten wir Ihnen PDZ and LIM Domain 5 Antikörper (70) und PDZ and LIM Domain 5 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PDLIM5 10611 Q96HC4
PDLIM5 56376 Q8CI51
Ratte PDLIM5 PDLIM5 64353 Q62920
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Top PDZ and LIM Domain 5 Proteine auf antikoerper-online.de

Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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PDLIM5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu PDZ and LIM Domain 5 (PDLIM5) Interaktionspartnern

Human PDZ and LIM Domain 5 (PDLIM5) Interaktionspartner

  1. this study shows functional importance of PDLIM5 for proper kAE1 membrane residency, as a crucial linker between kidneyAE1 and actin cytoskeleton-associated proteins in polarized cells

  2. PDLIM5 promotes papillary thyroid carcinoma via activation of the Ras-ERK pathway.

  3. PDLIM5 was strongly up-regulated during cardiomyogenesis and novel stage-specific isoforms were detected for PDLIM5

  4. Findings provide evidence of shared genetic variants in PDLIM5 gene influencing alcohol dependence, type 2 diabetes, and hypertension.

  5. The study provides evidence of several genetic variants within the PDLIM5 gene and interactions between PDLIM5 and steroid use influencing cancer.

  6. It can be deduced that the nonsynonymous rs7690296 polymorphism of PDLIM5 could play an important role in the pathophysiology of both bipolar disorder and schizophrenia.

  7. PDLIM5 (rs17021918,T), SLC22A3 (rs9364554,C) and NKX3-1 (rs1512268,A) SNPs might not be associated with prostate cancer in Chinese men.

  8. The significant difference in expression of PDLIM5 mRNA in the peripheral blood leukocytes of treatment-naive bipolar (BPD) patients versus that of healthy control subjects suggests that it may be a good biological marker for BPD.

  9. LIM domains have a novel molecular function: the regulation of PKC activities in a PKC isoform-specific manner.

  10. Altered expression of LIM was found in brains and lymphoblastoid cells from patients with bipolar disorder.

  11. It is confirmed a decreased expression of LIM in the lymphoblastoid cell lines from patients with bipolar I disorder and schizophrenia.

  12. Western blot studies of muscle tissues revealed that ENH4 is present only in skeletal muscle and there is a specific distribution of ENH members between skeletal and cardiac muscles, which is different in human and mouse.

  13. Genetic association study revealed the association of single nucleotide polymorphism (SNP)1 (rs10008257) with bipolar disorder.

  14. ENH is a restraining factor of the oncogenic activity of inhibitor of DNA binding 2 proteins in neural tumors

  15. Our investigation indicates that the lower expression levels of LIM mRNA in the peripheral leukocytes are associated with the depressive state and that its recovery after treatment may be an adaptive change induced by the antidepressant.

  16. We suggest that the higher expression levels of the PDLIM5 mRNA in the peripheral leukocytes may be a candidate marker for medication-free schizophrenic patients.

  17. our results provide further evidence to support PDLIM5 as a potential susceptible gene for schizophrenia

  18. PDLIM5 gene is associated with recurrent major depressive disorder.

  19. tested for an association between three single nucleotide polymorphisms at the PDLIM5 gene and lithium prophylaxis in a Sardinian sample comprised of 155 bipolar patients treated with lithium

  20. PDLIM5 may have a minor effect on susceptibility to bipolar disorder in Caucasians.

Mouse (Murine) PDZ and LIM Domain 5 (PDLIM5) Interaktionspartner

  1. These results reveal a E2F1/miR-17-92/ENH1/Id1 regulatory axis during myogenesis.

  2. Collectively, our results suggest that ENH1 plays an important role in the activation of myogenesis through the repression of Id2 activity.

  3. Cypher and ENH redundantly play an essential role in sustaining Z-line structure from the earliest stages of cardiac function, and are redundantly required to maintain normal embryonic heart function and embryonic viability.

  4. PDLIM5 is involved in psychiatric disorders, including mood disorders

  5. ENH1 with multiple protein-protein interaction modules is essential for differentiation of striated muscles, whereas ectopic expression of LIM domain-less ENH disrupts normal muscle differentiation.

  6. coordinated and stepwise splicing transitions result in the production of specific ENH transcripts in mature striated muscles.

  7. Deletion of ENH leads to destabilization of this protein complex and dilated cardiomyopathy in mice.

  8. Antagonistic splice variants of enigma may play a central role in the adaptive changes of the link between mechanical stress-sensing and signalling occurring during embryonic development and/or heart hypertrophy.

  9. Western blot studies of muscle tissues revealed that ENH4 is present only in skeletal muscle and there is a specific distribution of ENH members between skeletal and cardiac muscles, which is different in human and mouse.

  10. These results identify Enigma as a novel APS-binding protein and suggest that the APS/Enigma complex plays a critical role in actin cytoskeleton organisation.

  11. ENH is a restraining factor of the oncogenic activity of inhibitor of DNA binding 2 proteins in neural tumors

Zebrafish PDZ and LIM Domain 5 (PDLIM5) Interaktionspartner

  1. findings show the temporal & spatial expression patterns of the 3 Enigma family members & their PDZ & LIM domain encoding splice forms during embryogenesis

PDZ and LIM Domain 5 (PDLIM5) Protein Überblick

Protein Überblick

This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PDZ and LIM Domain 5 Proteine (PDLIM5)

  • PDZ and LIM domain 5 (PDLIM5)
  • PDZ and LIM domain 5 (Pdlim5)
  • PDZ and LIM domain 5b (pdlim5b)
  • PDZ and LIM domain 5a (pdlim5a)
  • PDZ and LIM domain 5 (pdlim5)
  • PDZ and LIM domain 5 L homeolog (pdlim5.L)
  • 1110001A05Rik Protein
  • AI987914 Protein
  • C87059 Protein
  • Enh Protein
  • enh1 Protein
  • Enh2 Protein
  • Enh3 Protein
  • LIM Protein
  • MGC97610 Protein
  • PDLIM5 Protein
  • zgc:56116 Protein
  • zgc:86712 Protein
  • zgc:91978 Protein

Bezeichner auf Proteinebene für PDZ and LIM Domain 5 Proteine (PDLIM5)

PDZ and LIM domain protein 5 , enigma homolog , enigma-like LIM domain protein , enigma-like PDZ and LIM domains protein , PDZ and LIM domain 5 , DKEYP-100D11.1 , ENH , PDZ and LIM domain protein 5-like

GENE ID SPEZIES
10611 Homo sapiens
56376 Mus musculus
64353 Rattus norvegicus
393165 Danio rerio
422699 Gallus gallus
436927 Danio rerio
461385 Pan troglodytes
478482 Canis lupus familiaris
548530 Xenopus (Silurana) tropicalis
100053510 Equus caballus
100101292 Xenopus laevis
100351774 Oryctolagus cuniculus
100442749 Pongo abelii
100466644 Ailuropoda melanoleuca
100597048 Nomascus leucogenys
503621 Bos taurus
100732952 Cavia porcellus
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