anti-PDZ Domain Containing 1 (PDZK1) Antikörper

PDZK1 encodes a PDZ domain-containing scaffolding protein. Zusätzlich bieten wir Ihnen PDZK1 Proteine (6) und PDZK1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDZK1 5174 Q5T2W1
PDZK1 59020 Q9JIL4
PDZK1 65144 Q9JJ40
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Top anti-PDZK1 Antikörper auf antikoerper-online.de

Showing 10 out of 121 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PDZK1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-PDZK1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate <br /> PDZK1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Rind (Kuh) Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), SimWes, WB 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with PDZK1 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of PDZK1 Antibody (Center) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the PDZK1 antibody detected the PDZK1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western Blot at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane. PDZK1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$550.00
Details
Human Maus Unkonjugiert ELISA, FACS, ICC, IF, WB Flow Cytometry: PDZK1 Antibody (1A2) [NBP2-22568] - Analysis of PDZK1 in Hep3B cell line, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line). Immunocytochemistry/Immunofluorescence: PDZK1 Antibody (1A2) [NBP2-22568] - Analysis of PDKZ1 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PDKZ1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$415.44
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details

PDZK1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PDZK1 Antikörper

  1. Cow (Bovine) Polyclonal PDZK1 Primary Antibody für ICC, IF - ABIN152917 : Lan, Silver: Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal PDZK1 Primary Antibody für IHC (p), ELISA - ABIN562170 : Walker, MacLeod, Williams, Cameron, Smyth, Langdon: Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer. in Gynecologic oncology 2007 (PubMed)

Weitere Antikörper gegen PDZK1 Interaktionspartner

Human PDZ Domain Containing 1 (PDZK1) Interaktionspartner

  1. These findings have provided first lines of evidences that PDZK1 expression is negatively correlated with SHP-1 activation and poor clinical outcomes in clear cell renal cell carcinoma (ccRCC) . PDZK1 was identified as a novel tumor suppressor in ccRCC by negating SHP-1 activity

  2. HNF1alpha (zeige HNF1A Antikörper), which has previously been described as a modulator of several transporters of the renal transportosome, is also a key determinant of PDZK1 transcription.

  3. a PDZK1 single nucleotide polymorphism rs12129861 was found to be significantly associated with gout susceptibility (meta-analysis)

  4. PDZK1 was defined as an independent prognostic factor for both OS and DFS (zeige FST Antikörper). These findings indicated that low level of PDZK1 could predict poor clinical outcome in patients with ccRCC.

  5. Inflammation-induced loss of PDZK1 expression may contribute to the NHE3 (zeige SLC9A3 Antikörper) dysfunction observed in the inflamed intestine.

  6. PARP (zeige COL11A2 Antikörper) regulates estradiol-mediated cell growth by controlling the ER/IGF-1R (zeige IGF1R Antikörper)/PDZK1 axis.

  7. PDZK1, negatively regulates 5-HT2AR endocytosis and has no effect upon 5-HT2AR-mediated ERK1/2 phosphorylation.

  8. Described is a structure of D-AKAP2 (zeige AKAP10 Antikörper) in complex with two interacting partners and the exact mechanism by which a segment that on its own is disordered presents an alpha-helix to PKA and a beta (zeige SUCLA2 Antikörper)-strand to PDZK1.

  9. PDZK1 and NHERF1 regulate the transport function of OATP1A2 by modulating protein internalization via a clathrin-dependent pathway and by enhancing protein stability.

  10. Correlation between PDZK1, Cdc37 (zeige CDC37 Antikörper), Akt (zeige AKT1 Antikörper) and breast cancer malignancy: the role of PDZK1 in cell growth through Akt (zeige AKT1 Antikörper) stabilization by increasing and interacting with Cdc37 (zeige CDC37 Antikörper)

Mouse (Murine) PDZ Domain Containing 1 (PDZK1) Interaktionspartner

  1. These results suggest that the PDZ domain (zeige INADL Antikörper) of PICK1 (zeige PICK1 Antikörper) directly interacts with calcineurin B (zeige CAN Antikörper) in osteoclast progenitor cells and promotes osteoclast differentiation through activation of calcineurin-NFAT (zeige NFATC1 Antikörper) signaling.

  2. Inflammation-induced loss of PDZK1 expression may contribute to the NHE3 (zeige SLC9A3 Antikörper) dysfunction observed in the inflamed intestine.

  3. PDZK1 has novel SR-BI (zeige SCARB1 Antikörper)-independent function in VSM that affords protection from neointima formation, and this involves PDZK1 suppression of VSM cell proliferation via an inhibitory interaction with Bcr (zeige BCR Antikörper)

  4. Data show that interaction of the inducible nitric oxide synthase (iNOS (zeige NOS2 Antikörper)) C-terminus with the PDZ (zeige INADL Antikörper) domains of EBP50 (zeige SLC9A3R1 Antikörper) protein or Pdzk1 protein CAP70 resulted greater nitric oxide (NO) synthesis.

  5. PDZK1 regulates intracellular trafficking of Oatp1a1 (zeige Slco1a1 Antikörper).

  6. PDZK1(NHERF3) is entirely non-raft associated with lipid rafts in brush border membrane fractions of NHE3 (zeige SLC9A3 Antikörper).

  7. NHERF3 is a key regulator of organic transport in the kidney, particularly MRP4-mediated clearance of drug molecules.

  8. SR-BI (zeige SCARB1 Antikörper) and PDZK1 protein and mRNA expression levels fell rapidly in primary hepatocyte cultures, indicating this system does not adequately mimic hepatocytes in vivo for analysis of the PDZK1 dependence of SR-BI (zeige SCARB1 Antikörper).

  9. the localization of PDZK1 on hepatocyte cell surface membranes in vivo is dependent on its PDZ4 domain and the presence of SR-BI (zeige SCARB1 Antikörper).

  10. The impairment of the absorptive function of the inflamed colon in the IL-10 (zeige IL10 Antikörper)(-/-) mouse, in spite of unaltered NHE3 (zeige SLC9A3 Antikörper) expression and localization, is accompanied by the downregulation of the NHE3 (zeige SLC9A3 Antikörper)-regulatory PDZ (zeige INADL Antikörper) adaptors NHERF2 (zeige SLC9A3R2 Antikörper) and PDZK1.

PDZK1 Antigen-Profil

Protein Überblick

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit PDZK1

  • PDZ domain containing 1 (PDZK1) Antikörper
  • PDZ domain containing 1 L homeolog (pdzk1.L) Antikörper
  • PDZ domain containing 1 (pdzk1) Antikörper
  • PDZ domain containing 1 (Pdzk1) Antikörper
  • 1700023D20Rik Antikörper
  • 2610507N21Rik Antikörper
  • 4921513F16Rik Antikörper
  • AI267131 Antikörper
  • AI314638 Antikörper
  • AL022680 Antikörper
  • CAP70 Antikörper
  • Clamp Antikörper
  • D3Ertd537e Antikörper
  • mPDZK1 Antikörper
  • NHERF-3 Antikörper
  • NHERF3 Antikörper
  • Pdzd1 Antikörper
  • PDZK1 Antikörper
  • xpdzk1 Antikörper

Bezeichner auf Proteinebene für PDZK1

PDZ domain containing 1 , Na(+)/H(+) exchange regulatory cofactor NHE-RF3-like , CFTR-associated protein of 70 kDa , Na(+)/H(+) exchange regulatory cofactor NHE-RF3 , PDZ-containing kidney protein 1 , na/Pi cotransporter C-terminal-associated protein 1 , naPi-Cap1 , sodium-hydrogen exchanger regulatory factor 3 , NHERF-3 , Na(+)/H(+) exchanger regulatory factor 3 , PDZ domain-containing protein 1 , PDZK1-like protein , C-terminal linking and modulating protein , C-terminal-linking and modulating protein , dietary Pi-regulated RNA-1 , diphor-1

GENE ID SPEZIES
418460 Gallus gallus
446272 Xenopus laevis
696698 Macaca mulatta
100065636 Equus caballus
100145801 Xenopus (Silurana) tropicalis
100152549 Sus scrofa
100403156 Callithrix jacchus
100482698 Ailuropoda melanoleuca
100012609 Monodelphis domestica
100588075 Nomascus leucogenys
100611671 Pan troglodytes
5174 Homo sapiens
59020 Mus musculus
475823 Canis lupus familiaris
534439 Bos taurus
100008900 Oryctolagus cuniculus
65144 Rattus norvegicus
100173285 Pongo abelii
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