ORM1-Like 3 (S. Cerevisiae) (ORMDL3) ELISA Kits

Negative regulator of sphingolipid synthesis. Zusätzlich bieten wir Ihnen ORMDL3 Antikörper (24) und ORMDL3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ORMDL3 94103 Q8N138
Anti-Maus ORMDL3 ORMDL3 66612 Q9CPZ6
Anti-Ratte ORMDL3 ORMDL3 360618 Q6QI25
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für ORMDL3 Interaktionspartner

Human ORM1-Like 3 (S. Cerevisiae) (ORMDL3) Interaktionspartner

  1. These associations with ORMDL3 are cell type specific, with the most significant 17q21 genotype effects on ORMDL3 expression and HSPA5 (zeige HSPA5 ELISA Kits) induction evident in B cells. Together, these findings have implications for how the interaction of increased ORMDL3 and rhinovirus may predispose to asthma.

  2. Chromosome 17q21 genes ORMDL3 and GSDMB are linked to asthma and other immune diseases. (Review)

  3. The results confirmed that polymorphisms in NOD2 (zeige NOD2 ELISA Kits) (Leu1007insC) and IRGM genes are associated with increased risk of Crohn's disease; whereas the ORMDL3 variant is associated with susceptibility to ulcerative colitis in the Lithuanian early-onset inflammatory bowel disease population.

  4. IRF-3 (zeige IRF3 ELISA Kits) is an important regulator of ORMDL3 induction following RSV infection by binding directly to the promoter of ORMDL3

  5. MiR (zeige MLXIP ELISA Kits)-665 induced apoptosis by inhibiting XBP1 (zeige XBP1 ELISA Kits) and ORMDL3.

  6. These studies suggest that increased levels of ORMDL3 contribute to antiviral defense to rhinovirus infection in mice (hORMDL3(zp3 (zeige ZP3 ELISA Kits)-Cre) mice which have universal increased expression of human ORMDL3) through pathways that may include IFNs (IFN-alpha (zeige IFNA ELISA Kits), IFN-beta (zeige IFNB1 ELISA Kits), IFN-lambda), OAS (zeige SMOC1 ELISA Kits), and RNAse L (zeige RNASEL ELISA Kits).

  7. this study demonstrated the upregulation of (zeige ATF6 ELISA Kits) ORMDL3 (zeige BECN1 ELISA Kits)in patients with systemic lupus erythematosus

  8. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  9. modest changes (8-13%) in promoter methylation levels of ZPBP2 and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 and ORMDL3 is mediated by DNA methylation

  10. Decreased ORMDL3 expression increased levels of free sphingoid bases and sphingoid base phosphates, and also caused increases in cellular levels of ceramides.

Mouse (Murine) ORM1-Like 3 (S. Cerevisiae) (ORMDL3) Interaktionspartner

  1. Expression levels of ORMDL3, phosphorylated (p)ERK (zeige EPHB2 ELISA Kits) and MMP9 (zeige MMP9 ELISA Kits) were significantly greater in the asthmamodel group; however, in the group pretreated with budesonide their expression was reduced.

  2. ORMDL3 mediates the autophagy via the ATF 6 (zeige ATF6 ELISA Kits)-Beclin1 (zeige BECN1 ELISA Kits) autophagy pathway, and it facilitates the survival of splenic B cells via promoting autophagy and suppressing apoptosis

  3. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  4. inhibiting ORMDL3 in airway epithelial cells plays a significant role in induction of allergen-induced increases in airway hyperresponsiveness

  5. ORMDL3, an asthma susceptibility gene identified by genome-wide association studies, contributes to key pathways that promote changes in airway physiology during allergic immune responses.

  6. Mediated by GATA3 (zeige GATA3 ELISA Kits) through targeting promoter region of ORMDL3.

  7. Downregulation of ORMDL3 expression in mast cells enhances AKT (zeige AKT1 ELISA Kits) and NF-kappaB (zeige NFKB1 ELISA Kits)-directed signaling pathways and chemotaxis and contributes to the development of mast cell-mediated local inflammation in vivo.

  8. overexpression of ORMDL3 regulates ceramide homeostasis in cells in a complex manner and suggest that local FTY720 administration might be a useful therapeutic intervention for the control of allergic asthma.

  9. the contribution of ORMDL3 to asthma risk may involve changes in sphingolipid metabolism

  10. These studies provide evidence that ORMDL3 plays an important role in vivo in airway remodeling potentially through ATF6 (zeige ATF6 ELISA Kits) target genes.

ORMDL3 Antigen-Profil

Beschreibung des Gens

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).

Genbezeichner und Symbole assoziert mit ORMDL3

  • ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) Antikörper
  • ORM1-like 3 (S. cerevisiae) (Ormdl3) Antikörper
  • ORMDL sphingolipid biosynthesis regulator 3 (Ormdl3) Antikörper
  • 2810011N17Rik Antikörper
  • AI315223 Antikörper
  • LRRGT00183 Antikörper

Bezeichner auf Proteinebene für ORMDL3

ORM1-like protein 3 , liver regeneration-related protein LRRGT00183

94103 Homo sapiens
66612 Mus musculus
360618 Rattus norvegicus
615368 Bos taurus
100479284 Ailuropoda melanoleuca
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