Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 Proteine (NUDT21)

The protein encoded by NUDT21 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. Zusätzlich bieten wir Ihnen Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 Antikörper (47) und Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NUDT21 11051 O43809
NUDT21 68219 Q9CQF3
NUDT21 291877 Q4KM65
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Showing 10 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
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Hefe Arabidopsis thaliana His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,365.00
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,566.67
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,566.67
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Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,566.67
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Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,572.17
Details

NUDT21 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 (NUDT21) Interaktionspartnern

Human Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 (NUDT21) Interaktionspartner

  1. RNA sequence preferences of unconventional RNA-binding proteins, Nudt21 and CNBP (zeige CNBP Proteine), has been described.

  2. Loss of NUDT21 shortened the 3'-UTR of various oncogenes in hepatocellular carcinoma cells. The shorter 3'-UTR contained less miRNA binding sites, which enabled the oncogenes to evade miRNA regulation and become overexpressed in HCC (zeige FAM126A Proteine), leading to unregulated cancer cell proliferation.

  3. it was demonstrated that the CFIm25 protein was also downregulated in osteosarcoma tissues, and inhibited the proliferation and promoted the apoptosis of the cells. Elucidating the roles of miR181a and CFIm25 in osteosarcoma not only assists in further understanding the pathogenesis and progression of this disease, but also offers novel targets for effective therapies.

  4. The authors identify NUDT21 as a novel candidate for intellectual disability and neuropsychiatric disease, and elucidate a mechanism of pathogenesis by MeCP2 dysregulation via altered alternative polyadenylation.

  5. Crystal structure of CFIm25-CFIm68 (zeige CPSF6 Proteine) RRM heterotetramer illustrated that CFIm25 homodimer is clamped by two CFIm68 (zeige CPSF6 Proteine) monomers on each side of the dimer interface.

  6. Data provide evidence that CFIm (zeige CPSF6 Proteine) exists as a heterotetramer of 25-kD, 59-kD and 68-kD subunits of CFIm (zeige CPSF6 Proteine): CFIm25, CFIm59 (zeige CPSF7 Proteine) and CFIm68 (zeige CPSF6 Proteine).

  7. crystal structures of the CFI (zeige CFI Proteine)(m)25 homodimer in complex with UGUAAA and UUGUAU RNA sequences

  8. Evidence that CFIm25 regulates alternative poly(A) site selection of genes with tandem poly(A) signals in their 3'-UTRs.

  9. The crystal structure of human CPSF5 was solved at 1.9 A resolution.

Mouse (Murine) Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 (NUDT21) Interaktionspartner

  1. Here we report that the CFIm (zeige CPSF6 Proteine) subunits NUDT21/CPSF5 and CPSF6 (zeige CPSF6 Proteine) are highly enriched in mouse male germ cells relative to somatic cells.

Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 (NUDT21) Protein Überblick

Protein Überblick

The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.

Genbezeichner und Symbole assoziert mit NUDT21

  • nudix hydrolase 21 (NUDT21)
  • nudix (nucleoside diphosphate linked moiety X)-type motif 21 (Nudt21)
  • nudix hydrolase 21 (Nudt21)
  • nudix hydrolase 21 (nudt21)
  • nudix hydrolase 21 L homeolog (nudt21.L)
  • cleavage and polyadenylation specificity factor subunit 5 (ANI_1_1518144)
  • cleavage and polyadenylation specificity factor subunit 5 (AOR_1_2312154)
  • cleavage and polyadenylation specificity factor subunit 5 (PTRG_11035)
  • cleavage and polyadenylation specificity factor subunit 5 (PAAG_04662)
  • cleavage and polyadenylation specificity factor subunit 5 (MCYG_02022)
  • cleavage and polyadenylation specificity factor subunit 5 (VDBG_06706)
  • cleavage and polyadenylation specificity factor subunit 5 (MGYG_04057)
  • cleavage and polyadenylation specific factor 5 (cpsf5)
  • autocrine motility factor receptor (PGTG_05353)
  • cleavage and polyadenylation specificity factor subunit 5 (Tsp_03672)
  • cleavage and polyadenylation specific factor 5 (LOC732888)
  • cleavage and polyadenylation specific factor 5 (AFUA_5G02030)
  • cleavage and polyadenylation specific factor 5 (NFIA_040090)
  • cleavage and polyadenylation specific factor 5 (ACLA_003240)
  • cleavage and polyadenylation specific factor 5 (CC1G_07993)
  • cleavage and polyadenylation specific factor 5 (PMAA_039710)
  • cleavage and polyadenylation specific factor 5 (AFLA_025180)
  • cleavage and polyadenylation specific factor 5 (TSTA_079060)
  • cleavage and polyadenylation specific factor 5 (BDBG_01565)
  • cleavage and polyadenylation specific factor 5 (TERG_04393)
  • nudix hydrolase homolog 21 (NUDT21)
  • 25kDa Protein
  • 3110048P04Rik Protein
  • 5730530J16Rik Protein
  • Afu5g02030 Protein
  • An16g01870 Protein
  • AO090003001316 Protein
  • atnudt21 Protein
  • AU014860 Protein
  • AW549947 Protein
  • CFIM25 Protein
  • cpsf5 Protein
  • nudix hydrolase homolog 21 Protein
  • T9L24.30 Protein
  • T9L24_30 Protein
  • zgc:63966 Protein

Bezeichner auf Proteinebene für NUDT21

CPSF 25 kDa subunit , cleavage and polyadenylation specific factor 5, 25 kD subunit , cleavage and polyadenylation specific factor 5, 25 kDa , cleavage and polyadenylation specificity factor 25 kDa subunit , cleavage and polyadenylation specificity factor subunit 5 , cleavage factor Im complex 25 kDa subunit , nucleoside diphosphate-linked moiety X motif 21 , nudix motif 21 , pre-mRNA cleavage factor Im (25kD) , pre-mRNA cleavage factor Im 25 kDa subunit , pre-mRNA cleavage factor Im, 25kD subunit , cleavage and polyadenylation specific factor 5 , Cleavage and polyadenylation specificity factor 5 , cleavage and polyadenylation specificity factor subunit 5-like

GENE ID SPEZIES
11051 Homo sapiens
68219 Mus musculus
291877 Rattus norvegicus
394092 Danio rerio
444830 Xenopus laevis
4988580 Aspergillus niger CBS 513.88
5992362 Aspergillus oryzae RIB40
6349347 Pyrenophora tritici-repentis Pt-1C-BFP
9096568 Paracoccidioides sp. 'lutzii' Pb01
9229141 Arthroderma otae CBS 113480
9537188 Verticillium alfalfae VaMs.102
10029169 Arthroderma gypseum CBS 118893
100172645 Pongo abelii
100301863 Oncorhynchus mykiss
100528826 Ictalurus punctatus
10534307 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10910141 Trichinella spiralis
732888 Bombyx mori
3505522 Aspergillus fumigatus Af293
4593152 Neosartorya fischeri NRRL 181
4708488 Aspergillus clavatus NRRL 1
6014831 Coprinopsis cinerea okayama7130
7028602 Talaromyces marneffei ATCC 18224
7909208 Aspergillus flavus NRRL3357
8102520 Talaromyces stipitatus ATCC 10500
8507179 Ajellomyces dermatitidis SLH14081
10379768 Trichophyton rubrum CBS 118892
518859 Bos taurus
478123 Canis lupus familiaris
843688 Arabidopsis thaliana
100858636 Gallus gallus
Ausgewählte Anbieter für Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 Proteine (NUDT21)
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