anti-Nuclear LaMiN Family Member (Lmn-1) (LMN-1) Antikörper

Major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane.

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LMN-1 172687 Q21443
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Caenorhabditis elegans Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$532.07
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LMN-1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Caenorhabditis elegans (C. elegans)


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Caenorhabditis elegans (C. elegans) Nuclear LaMiN Family Member (Lmn-1) (LMN-1) Interaktionspartner

  1. The Caenorhabditis elegans lamin, LMN-1, is required for nuclear migration and interacts with the nucleoplasmic domain of the SUN protein UNC-84.

  2. In LMN-1 Y59C (a point mutation)-expressing worms, there is abnormal retention at the nuclear envelope of a gene array bearing a muscle-specific (zeige EIF3K Antikörper) promoter. This correlates with altered expression of a number of muscle-specific (zeige EIF3K Antikörper) genes.

  3. A laminopathic mutation disrupting lamin (zeige LMNA Antikörper) filament assembly causes disease-like phenotypes in Caenorhabditis elegans.

  4. Both lamin Dm0 and C. elegans Ce-lamin bind directly to histone H2A in vitro and this binding requires a nuclear localization signal

Nuclear LaMiN Family Member (Lmn-1) (LMN-1) Antigen-Profil

Protein Überblick

Major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Provides a framework for the nuclear envelope and probably also interacts with chromatin. Essential to maintain the shape and integrity of the nucleus, and for DNA replication. Involved in spatial organization of nuclear pore complexes. It is not a target for ced-3 during apoptosis, suggesting that lamin cleavage is not essential for apoptosis in C.elegans.

Genbezeichner und Symbole assoziert mit LMN-1

  • Lamin-1 (lmn-1) Antikörper
GENE ID SPEZIES
172687 Caenorhabditis elegans
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