Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. Zusätzlich bieten wir Ihnen NFIB Antikörper (54) und NFIB Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Showing 3 out of 13 products:
Study highlighted the paradoxical involvement of NFIB in both the inhibition and promotion of tumor development as well as progression in different malignancies; especially between different tumor subtypes within a single organ system, such as in lung, brain and skin,which corroborates its diverse and distinct roles in specific tissues and cell types. [review]
Expression of the MYB (zeige MYB ELISA Kits)-NFIB fusion oncogene (zeige RAB1A ELISA Kits) in mammary tissue resulted in hyperplastic glands that developed into adenocarcinoma.
we report that the transcription factor NFIB is associated with significantly improved survival in glioblastoma
A trend toward superior PFS was noted with the MYB (zeige MYB ELISA Kits)/NFIB rearrangement, although this was not statistically significant. NGS revealed three tumors with 4q12 amplification, producing increased copies of axitinib-targeted genes PDGFR (zeige PDGFRB ELISA Kits)/KDR (zeige KDR ELISA Kits)/KIT.
High NFIB levels are associated with expansive growth of a poorly differentiated and almost exclusively E-cadherin (CDH1 (zeige CDH1 ELISA Kits))-negative invasive tumor cell population.
low expression of NFIB was significantly associated with biologically more aggressive subtypes and, ultimately, poorer survival in lung adenocarcinoma patients
Data indicate that NFIB protein increases EZH2 (zeige EZH2 ELISA Kits) protein expression downstream of BRN2 (zeige POU3F2 ELISA Kits) protein, which further decreases MITF (zeige MITF ELISA Kits) protein levels.
Our study defines new molecular subclasses of ACC (zeige ACACA ELISA Kits) characterized by MYBL1 (zeige MYBL1 ELISA Kits) rearrangements and 5'-NFIB gene fusions.
In benign prostatic hyperplasia, luminal NFIB loss correlated with more severe disease. in androgen-dependent LNCaP prostate cancer cells demonstrated that 64.3% of NFIB binding sites are associated with AR and FOXA1 binding sites.
These data suggest that germline genetic variation at rs7034162 is important in osteosarcoma metastasis and that NFIB is an osteosarcoma metastasis susceptibility gene.
Loss of Nfib resulted in a severe delay in intermediate progenitor cell generation while, conversely, overexpression of NFIX (zeige MLZE ELISA Kits) led to precocious intermediate progenitor cell generation.
Knockdown of NFIB in Drosha (zeige DROSHA ELISA Kits)-deficient hippocampal neural stem cells restores neurogenesis, suggesting that the Drosha (zeige DROSHA ELISA Kits)/NFIB mechanism robustly prevents oligodendrocyte fate acquisition in vivo.
Nfib is necessary and sufficient to increase chromatin accessibility at a large subset of the intergenic regions. Nfib promotes pro-metastatic neuronal gene expression programs and drives the metastatic ability of small cell lung cancer cells.
Loss of Nfib expression resulted in prostatic hyperplasia. NFIB knockdown studies demonstrated that loss of NFIB drives increased AR expression and superinduction of a subset of AR target genes.
Identify regulatory link between Nkx2-1 (zeige NKX2-1 ELISA Kits), miR (zeige MLXIP ELISA Kits)-200c, and the transcription factors Nfib and Myb (zeige MYB ELISA Kits), adding new players to the regulatory mechanisms driven by Nkx2-1 (zeige NKX2-1 ELISA Kits) in lung epithelial cells that may have implications in lung development and tumorigenesis.
NFIA (zeige NFIA ELISA Kits) and NFIB are endogenously expressed in gradients with high caudo-medial to low rostro-lateral expression ... this expression pattern deviates from that of PAX6 (zeige PAX6 ELISA Kits), suggesting that PAX6 (zeige PAX6 ELISA Kits) does not drive Nfi (zeige NFIC ELISA Kits) expression
NFIB-STAT5 (zeige STAT5A ELISA Kits) modules, possibly in conjunction with other transcription factors, control cell-specific genetic programs.
Study revealed both novel and broad functions of NFIB in regulating the generation of cortical projection neurons, including radial glial differentiation, neuronal migration and axon projection
downregulation of Ezh2 (zeige EZH2 ELISA Kits) transcription by NFIB is an important component of the process of neural progenitor cell differentiation during cortical development
Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
nuclear factor I/B
, nuclear factor 1 B-type-like
, nuclear factor I-B1
, CCAAT-box binding transcription factor
, CCAAT-box-binding transcription factor
, TGGCA-binding protein
, nuclear factor 1 B-type
, nuclear factor 1/B
, olfactory epithelium nuclear factor I-B