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NFIA encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Zusätzlich bieten wir Ihnen NFIA Antikörper (66) und NFIA Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
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The consistent overlap in clinical presentation provides further evidence of the critical role of NFIA haploinsufficiency in the development of the 1p32-p31 microdeletion syndrome phenotype.
Data define a previously unknown nuclear factor I-A-nuclear factor-kappaB feed-forward regulation that may contribute to glioblastoma cell survival.
Altogether, these results demonstrated that miR (zeige MLXIP ELISA Kits)-370 suppressed hepatitis B virus gene expression and replication through repressing NFIA expression, which stimulates hepatitis B virus replication via direct regulation on hepatitis B virus Enhancer I activities.
We verified that NFIA binds to the IGFBP2 promoter and transcriptionally enhances IGFBP2 expression levels. We identified that NFIA-mediated IGFBP2 signaling pathways are involved in miR-302b-induced glioma cell death.
miR (zeige MLXIP ELISA Kits)-191 was upregulated in patients with middle- and late-stage NSCLC, and in NSCLC cell lines, under mild hypoxic conditions. miR (zeige MLXIP ELISA Kits)-191 promoted the proliferation and migration of NSCLC under chronic hypoxic conditions, and this promotion may be associated with its targeting of NFIA.
Dihydrocapsaicin can significantly decrease proinflammatory cytokines through enhancing NFIA and inhibiting NF-kappaB (zeige NFKB1 ELISA Kits) expression
These results demonstrated that RP5833A20.1 inhibited tumor cell proliferation, induced apoptosis and inhibited cellcycle progression by suppressing the expression of NFIA in U251 cells.
NFI-A is involved in the miR (zeige MLXIP ELISA Kits)-21-induced expression of IL-10 (zeige IL10 ELISA Kits) in B cells in nasopharyngeal carcinoma; Il-10 (zeige IL10 ELISA Kits) is capable of suppressing CD8 (zeige CD8A ELISA Kits)+ T-cell activities.
microRNA-136 targeted and degraded NFIA, which induced the release of microRNA-223, promoting CD11b (zeige ITGAM ELISA Kits) expression. Direct base pairing occurs between miR (zeige MLXIP ELISA Kits)-136 and the 3' UTR (zeige UTS2R ELISA Kits) of NFIA mRNA.
this family also carried a microdeletion affecting solely the NFIA gene, this study substantiates the importance of this gene in craniofacial development.
Of these, NFIA emerged as the regulator yielding the strongest molecular and cellular phenotypes. To examine its regulatory function, we profiled the genomic localization of NFIA, identifying it as a key early regulator of terminal brown fat cell differentiation.
PAX6 (zeige PAX6 ELISA Kits) can substitute for LHX2 (zeige LHX2 ELISA Kits) and override NFIA-induced astrogliogenesis in developing hippocampus in vivo.
The NFIA identifies a subset of bipolar cells as well as Muller glia and astrocytes. During early postnatal development, NFIA labels astrocytes on the day of birth, AII (zeige ARG2 ELISA Kits) amacrine cells at postnatal (P) day 5, and Muller glia by P10, when horizontal cells also transiently exhibit NFIA immunofluorescence.
NFIA expression regulates glioma tumorigenesis and glia-specific enhancers enhancers contribute to glioma formation.
NFIA activates the cell-type-specific enhancers and facilitates the binding of PPARgamma (zeige PPARG ELISA Kits) to control the brown fat gene program.
Astrocyte induction by Zbtb20 is suppressed by knockdown of NFIA.
NFI-A disrupts myeloid cell differentiation and maturation in septic mice
NFIA and NFIB are endogenously expressed in gradients with high caudo-medial to low rostro-lateral expression ... this expression pattern deviates from that of PAX6, suggesting that PAX6 does not drive Nfi expression
RP5-833A20.1/miR (zeige MLXIP ELISA Kits)-382-5p/NFIA pathway was essential to the regulation of cholesterol homeostasis and inflammatory reactions.
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene.
nuclear factor I/A
, CCAAT-box-binding transcription factor
, TGGCA-binding protein
, nuclear factor 1 A-type
, nuclear factor 1/A
, nuclear factor I-A