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The protein encoded by NINJ2 belongs to the ninjurin (for nerve injury induced) family. Zusätzlich bieten wir Ihnen NINJ2 Antikörper (17) und NINJ2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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our study suggests that ninjurin2 is a novel regulator of endothelia inflammation and activation through TLR4 signaling pathways, and these data provided new insights into the mechanisms between NINJ2 and atherosclerosis.
the AA genotype carriers had significantly increased NINJ2 mRNA expression levels in the Chinese population, suggesting that the rs3809263 G > A polymorphism is a functional single nucleotide polymorphism and a biomarker for risk of large artery atherosclerotic stroke.
Data shows that common and rare variants in the NINJ2 region were nominally associated with incident ischemic stroke patients.
Risk of ischemic stroke was higher especially when the carriers of rs11833579 AA NINJ2 genotype were smokers.
Data suggest that the gene NINJ2 rs11833579 A/A or G/A genotype may bring forward the onset age of first-ever ischemic stroke without increasing silent cerebrovascular lesions prior to the stroke.
This meta-analysis suggest that rs12425791 is relative to ischemic stroke risk under dominant model in Asian population, but not for rs11833579.
In this meta-analysis, NINJ2 single-nucleotide polymorphism (SNP) rs12425791 is significantly associated with ischemic stroke in an East Asian (but not Chinese Han) population, of which A alleles increase the risk of ischemic stroke.
A new genetic variant rs10849373 located in the first intron of the NINJ2 gene confers risk of ischemic stroke in Chinese Han subjects.
12p13 SNPs rs11833579 and rs12425791 within NINJ2 gene do not seem to be associated with ischemic stroke in Chinese Han population
polymorphisms of the vascular susceptibility gene NINJ2 were associated with risk of Alzheimer's disease
There is a significant association between rs11833579 site polymorphism of the NINJ2 gene and risk for stroke in Han Chinese.
The protein encoded by this gene belongs to the ninjurin (for nerve injury induced) family. It is a cell surface adhesion protein that is upregulated in Schwann cells surrounding the distal segment of injured nerve, and promotes neurite outgrowth, thus may have a role in nerve regeneration after nerve injury.
, ninjurin 2
, nerve injury-induced protein 2