anti-Neuronal PAS Domain Protein 3 (NPAS3) Antikörper

NPAS3 encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NPAS3 64067 Q8IXF0
NPAS3 27386  
NPAS3 299016  
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Top anti-NPAS3 Antikörper auf antikoerper-online.de

Showing 10 out of 36 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with NPAS3 antibody ABIN214457 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with NPAS3 antibody ABIN213958 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$511.06
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$511.06
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunofluorescence: NPAS3 Antibody [NBP1-88622] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: NPAS3 Antibody [NBP1-88622] - Staining of human cerebellum shows moderate cytoplasmic and nuclear positivity in purkinje cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 12 bis 14 Tage
$593.40
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$350.00
Details

NPAS3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,


Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-NPAS3 Antikörper

  1. Human Polyclonal NPAS3 Primary Antibody für IHC, ELISA - ABIN1002931 : Kamnasaran, Muir, Ferguson-Smith, Cox: Disruption of the neuronal PAS3 gene in a family affected with schizophrenia. in Journal of medical genetics 2003 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal NPAS3 Primary Antibody für IHC, ELISA - ABIN1002930 : Brunskill, Witte, Shreiner, Potter: Characterization of npas3, a novel basic helix-loop-helix PAS gene expressed in the developing mouse nervous system. in Mechanisms of development 2000 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen NPAS3 Interaktionspartner

Human Neuronal PAS Domain Protein 3 (NPAS3) Interaktionspartner

  1. Study provides a clear, unbiased view of the full spectrum of genes regulated by NPAS1 (zeige NPAS1 Antikörper) and NPAS3 and shows that these transcription factors are master regulators of neuropsychiatric function. These findings expose the molecular pathophysiology of NPAS1 (zeige NPAS1 Antikörper)/3 mutations and provide a striking example of the shared, combinatorial nature of molecular pathways that underlie diagnostically distinct neuropsychiatric conditions.

  2. Here the authors examined the crystal structures of multi-domain NPAS1 (zeige NPAS1 Antikörper)-ARNT (zeige ARNT Antikörper) and NPAS3-ARNT (zeige ARNT Antikörper)-DNA complexes, discovering each to contain four putative ligand-binding pockets.

  3. Authors hypothesize that any nucleotide variant at the NPAS3 HAEs may lead to altered susceptibility to schizophrenia.

  4. Identification of NPAS3-V304I helps strengthen the hypothesis that NPAS3 is involved in schizophrenia pathogenesis

  5. The accelerated non-coding region 2xHAR142 of NPAS3 behaves as a developmental enhancer in the forebrain of transgenic mice.

  6. Results indicate that the high density of HAEs present in the human NPAS3 locus could have modified the spatiotemporal expression pattern of NPAS3 in the developing human brain and, therefore, contributed to human brain evolution.

  7. During human postnatal cortical development, there was decreased NPAS3 mRNA yet increased NPAS3 protein expression, suggesting the involvement of posttranscriptional regulation, which results show is modified by miR-17.

  8. In a HEK293 cell line over-expressing NPAS3, transcriptional targets varied with to circadian rhythm context & C-terminal deletion. NPAS3 contributes to neurodevelopmental transcription factor networks & the regulation of brain glucose metabolism.

  9. Loss of NPAS3 is associated with the progression of Astrocytomas.

  10. report of immunohistochemical findings on NPAS3 protein expression in the developing human fetal brain during the three trimesters (10-41 weeks) of gestational development

Mouse (Murine) Neuronal PAS Domain Protein 3 (NPAS3) Interaktionspartner

  1. Study provides a clear, unbiased view of the full spectrum of genes regulated by NPAS1 (zeige NPAS1 Antikörper) and NPAS3 and shows that these transcription factors are master regulators of neuropsychiatric function. These findings expose the molecular pathophysiology of NPAS1 (zeige NPAS1 Antikörper)/3 mutations and provide a striking example of the shared, combinatorial nature of molecular pathways that underlie diagnostically distinct neuropsychiatric conditions.

  2. Most NPAS3 immunofluorescence originated in the subgranular zone of the dentate gyrus with immunopositive processes radiating into the granule cell layer proper. Npas3 acts during neuronal maturation/differentiation.

  3. a regulatory program controlled in inhibitory interneurons by the NPAS1 (zeige NPAS1 Antikörper) and NPAS3 transcription factors may be either substantively or tangentially relevant to psychosis

  4. Npas3-/- mice are deficient in expression of hippocampal FGF receptor (zeige FGFR2 Antikörper) subtype 1 mRNA.

  5. our observations indicate an important role for Npas3 in controlling normal brain development and neurosignaling pathways

  6. NPAS3 is a trachealess homolog critical for lung development and homeostasis.

NPAS3 Antigen-Profil

Protein Überblick

This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and mental retardation. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit NPAS3

  • neuronal PAS domain protein 3 (npas3) Antikörper
  • neuronal PAS domain protein 3 (NPAS3) Antikörper
  • neuronal PAS domain protein 3 (Npas3) Antikörper
  • 4930423H22Rik Antikörper
  • bHLHe12 Antikörper
  • MGC145768 Antikörper
  • MOP6 Antikörper
  • PASD6 Antikörper
  • trh Antikörper

Bezeichner auf Proteinebene für NPAS3

neuronal PAS domain protein 3 , basic-helix-loop-helix-PAS protein , neuronal PAS domain-containing protein 3-like , PAS domain-containing protein 6 , basic-helix-loop-helix-PAS protein MOP6 , class E basic helix-loop-helix protein 12 , member of PAS protein 6 , neuronal PAS domain-containing protein 3 , neuronal PAS3

GENE ID SPEZIES
780104 Xenopus (Silurana) tropicalis
452849 Pan troglodytes
570491 Danio rerio
717281 Macaca mulatta
100012567 Monodelphis domestica
100388958 Callithrix jacchus
100550491 Meleagris gallopavo
100555253 Anolis carolinensis
100621114 Sus scrofa
64067 Homo sapiens
27386 Mus musculus
299016 Rattus norvegicus
423315 Gallus gallus
100688457 Canis lupus familiaris
527053 Bos taurus
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