Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) Proteine (NPR1)

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). Zusätzlich bieten wir Ihnen NPR1 Antikörper (97) und NPR1 Kits (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NPR1 4881 P16066
NPR1 24603 P18910
NPR1 18160 P18293
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Top NPR1 Proteine auf antikoerper-online.de

Showing 8 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,234.00
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Escherichia coli (E. coli) Human His-SUMO Tag   100 μg Anmelden zum Anzeigen 11 Days
$411.40
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Hefe Human His tag   100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$484.00
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Baculovirus infected Insect Cells Human GST tag   50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$624.55
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NPR1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , ,
Rat (Rattus)

Mouse (Murine)
,

Weitere Proteine zu Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) Interaktionspartnern

Human Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) Interaktionspartner

  1. These results of the distinct presence of NPRA and NPRBpositive cells in unstable plaques underlying acute myocardial infarction suggested that natriuretic peptides serve a role in regulating plaque instability in humans.

  2. The results indicate that the inhibition of NPRA suppresses gastric cancer development and targeting NPRA may represent a promising strategy for the treatment of gastric cancer.

  3. Data suggest that signaling via ANP (zeige NPPA Proteine)/ANPR (atrial natriuretic factor/ANP (zeige NPPA Proteine) receptor (zeige PPP5C Proteine)) in vascular endothelial cells activates PAK4 (p21-activated kinase 4 (zeige PAK4 Proteine)) and CCM2 (cerebral cavernous malformation 2 (zeige CCM2 Proteine) protein), resulting in phosphorylation of MLC (myosin light chain), cytoskeletal reorganization, and cell spreading; kinase homology domain of ANPRA (guanylyl cyclase-A) activates downstream targets of ANP (zeige NPPA Proteine)/ANPR signaling.

  4. After ligand binding, NPRA is rapidly internalized and trafficked from the cell surface into endosomes, Res and lysosomes, with concurrent generation of intracellular cyclic GMP (zeige NT5C2 Proteine) in HEK (zeige EPHA3 Proteine)-293 cells.

  5. Data suggest up-regulation of NPRA in skeletal muscle (SM) correlates with whole-body insulin sensitiv (zeige INS Proteine)ity; NPRA is down-regulated in SM in obese subjects compared to normal controls; NPRA in SM is up-regulated in response to diet-induced weight loss.

  6. In this review we highlight the mechanisms by which NPR-A affects signaling pathways involved in inflammation and cancer, and we discuss its potential as a novel target in inflammation, cancer, and cancer-related inflammation

  7. NPRA was detected in E11.5 cardiac progenitor cells.

  8. Cardiac fibrosis and the endogenous natriuretic peptide system were evaluated in end-stage heart failure to assess the anti-fibrotic actions of the dual GC-A/-B activator.

  9. High NPR1 expression is associated with esophageal squamous cell carcinomas.

  10. Molecular dynamics analysis indicated decreases in the values of Van (zeige TNIP1 Proteine) der (zeige GDF3 Proteine) Waals, electrostatic energy and potential energy of NPRB (zeige NPR2 Proteine)/Vasonatrin peptide compared to NPRA/Vasonatrin peptide.

Mouse (Murine) Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) Interaktionspartner

  1. A decreased Npr1 copy number enhanced the expression of hypertrophic markers.

  2. The results indicate that the inhibition of NPRA suppresses gastric cancer development and targeting NPRA may represent a promising strategy for the treatment of gastric cancer.

  3. KLF10 and atrial natriuretic peptide (zeige NPPA Proteine)/NPRA in exerting influences on chronic pulmonary disease pathogenesis

  4. Treatment of the haplotype Npr1(+/-) mice with histone deacetylase (zeige HDAC1 Proteine) inhibitors significantly lowered blood pressure and reduced the renal inflammation and fibrosis involving the interactive roles of HDAC1 (zeige HDAC1 Proteine)/2, NF-kappaB (zeige NFKB1 Proteine) (p65 (zeige NFkBP65 Proteine)), and STAT1 (zeige STAT1 Proteine).

  5. Data suggest that the negative inhibition of P2X3R activity by the BNP/NPR-A pathway results in a decreased P2X3R-mediated excitability of trigeminal neurons in wildetype cultures. In familial hemiplegic migraine type-1 model cultures, however, lack of efficient P2X3Rs downregulation contributes to the neuronal hyperexcitability phenotype.

  6. The results suggest that an antagonistic cascade exists between the TGF-beta1/Smad/deltaEF1 pathways and Npr1 expression and receptor signaling that is relevant to renal and vascular remodeling, and may be critical in the regulation of blood pressure and cardiovascular homeostasis.

  7. Conclude that postnatal cardiac hyperplasia in mice with global GC-A (zeige GUCA1A Proteine) inactivation is provoked by systemic alterations rather than direct regulation of cardiac myocyte proliferation.

  8. Data (including data from studies in knockout mice) suggest expression of ANP (zeige NPPA Proteine)/BNP/GC-A (zeige GUCA1A Proteine) (atrial natriuretic peptide (zeige NPPA Proteine), brain natriuretic peptide (zeige BNP Proteine), and guanylyl cyclase-A) is important in embryonic neovascularization and organogenesis.

  9. Suggest that the FQQI motif is essential for the internalization and subcellular trafficking of NPRA during the hormone signaling process in intact mesangial cells.

  10. Data suggest activation of skeletal muscle (SM) Npra is important for maintenance of long-term insulin (zeige INS Proteine) sensitivity; up-regulation of Npra signal transduction in SM (that was reduced by obesity) prevents glucose intolerance and diabetes type 2.

Arabidopsis thaliana Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) Interaktionspartner

  1. the characterization of a zinc-finger protein-coding gene AtOZF1 that positively influences NPR1-independent salicylic acid signaling, is reported.

  2. study not only provides a convenient and efficient transient expression system, but also reveals that NPR1-dependent SA signaling is a major barrier to efficient transient expression

  3. We identified a rice mutant in the Kitaake genetic background with a frameshift mutation in crk10; this mutant also displays a compromised immune response highlighting the important role of crk10. We also show that elevated levels of NH1 expression lead to enhanced CRK10 expression and that the rice TGA2.1 protein binds to the CRK10 promoter.

  4. Green tissue-specific expression of Arabidopsis thaliana NPR1 is an effective strategy for controlling the sheath blight pathogen (Rhizoctonia solani) in rice. The present work in rice can be extended to other crop plants severely damaged by the pathogen.

  5. The results revealed a tight correlation between sequential salicylic acid (SA) and sic acid (ABA) signaling and dynamic changes in NPR1 protein levels and NPR1-dependent transcription in plant immune responses.

  6. Crosstalk between nitric oxide and glutathione is integral to the NPR1-dependent defense signaling pathway.

  7. The authors show that sumoylation of NPR1 by SUMO3 (zeige SUMO3 Proteine) activates defense gene expression by switching NPR1's association with the WRKY transcription repressors to TGA (zeige TBX1 Proteine) transcription activators.

  8. Altogether, our results indicate that AR156 can induce SAR by the SA-signaling pathways in an NPR1-dependent manner and involves multiple PTI components.

  9. NPR1-dependent salicylic acid signaling is not involved in the elevated carbon dioxide-induced heat shock tolerance.

  10. NPR1-dependent salicylic acid (SA) signalling is central to the salt and oxidative stress tolerance in Arabidopsis.

NPR1 Protein Überblick

Protein Überblick

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994

Genbezeichner und Symbole assoziert mit NPR1

  • natriuretic peptide receptor 1 (NPR1)
  • natriuretic peptide receptor 1 (Npr1)
  • natriuretic peptide receptor 1a (npr1a)
  • regulatory protein (NPR1) (NPR1)
  • AI893888 Protein
  • ANPa Protein
  • Anpra Protein
  • ARABIDOPSIS NONEXPRESSER OF PR GENES 1 Protein
  • ATNPR1 Protein
  • F15H21.6 Protein
  • F15H21_6 Protein
  • GC-A Protein
  • Gca Protein
  • GUC2A Protein
  • GUCY2A Protein
  • NIM1 Protein
  • NON-INDUCIBLE IMMUNITY 1 Protein
  • NONEXPRESSER OF PR GENES 1 Protein
  • NPR-A Protein
  • Npra Protein
  • Pndr Protein
  • REGULATORY PROTEIN NPR1 Protein
  • SAI1 Protein
  • SALICYLIC ACID INSENSITIVE 1 Protein
  • sGC Protein
  • si:dkey-27c15.1 Protein

Bezeichner auf Proteinebene für NPR1

ANP-A , ANPR-A , GC-A , NPR-A , atrial natriuretic peptide receptor 1 , atrial natriuretic peptide receptor type A , atrionatriuretic peptide receptor A , guanylate cyclase A , natriuretic peptide A type receptor , natriuretic peptide receptor A , atrial natriuretic peptide A-type receptor , atrial natriuretic peptide receptor A , natriuretic peptide receptor 1 , aatriuretic peptide receptor A , guanylyl cyclase beta 1, soluable , natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) , Nppa receptor , guanylyl cyclase-A

GENE ID SPEZIES
4881 Homo sapiens
24603 Rattus norvegicus
560653 Danio rerio
100343663 Oryctolagus cuniculus
18160 Mus musculus
842733 Arabidopsis thaliana
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