NLR Family Member X1 (NLRX1) ELISA Kits

NLRX1 encodes a member of the NLR family. Zusätzlich bieten wir Ihnen NLRX1 Antikörper (70) und und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
NLRX1 79671 Q86UT6
Anti-Maus NLRX1 NLRX1 270151 Q3TL44
Anti-Ratte NLRX1 NLRX1 315599 Q5FVQ8
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für NLRX1 Interaktionspartner

Human NLR Family Member X1 (NLRX1) Interaktionspartner

  1. Data show that NLRX1 specifically interacts with FASTKD5 and colocalizes with mitochondrial RNA granules. Further results suggest an important role of NLRX1 in regulating the post-transcriptional processing of mitochondrial RNA, which may have an important implication in bioenergetic adaptation during metabolic stress, oncogenic transformation and innate immunity.

  2. genetic association studies in Han population in southern China: Data suggest that, in subjects with type 2 diabetes, an SNP in NLRX1 (rs4245191) is associated with macro-vascular complications and cerebral infarction in the population studied; no such association was found for two other SNPs in NLRX1 (rs10790286, rs561830) or for two SNPs in TRAF6 (rs5030445, rs16928973). (TRAF6 = TNF receptor associated factor-6)

  3. Data show that NLRX1 suppresses tumorigenesis and reveals new genetic pathways involved in the pathobiology of histiocytic sarcoma.

  4. NLRX1 exerted opposing regulatory effects on viral activation of the transcription factors IRF1 and IRF3. NLRX1 suppressed MAVS-mediated activation of IRF3, it conversely facilitated virus-induced increases in IRF1 expression and thereby enhanced control of viral infection.

  5. downregulated in brain injury following aneurysm

  6. The data suggests that NLRX1 plays a positive role in Kaposi's sarcoma-associated herpesvirus (KSHV) lytic replication by suppressing the IFNbeta response during the process of KSHV reactivation, which might serve as a potential target for restricting KSHV replication and transmission.

  7. we identify a novel signaling hub centering on the NLRX1 TUFM protein complex, promoting autophagic flux. Defects in the expression of either NLRX1 or TUFM result in compromised autophagy when treated with EGFR inhibitors.These findings expand our understanding of the components involved in head and neck squamous cell carcinoma autophagy machinery that responds to EGFR inhibitors.

  8. findings suggest that NLRX1 may function as a cardiac-protective molecule in myocardial ischemic injury by repressing inflammation and apoptosis

  9. NLRX1, NLRP12 and NLRC3 negatively modulate the host immune response following virus exposure. (Review)

  10. NLRX1 acts as a potential tumor suppressor by regulating the TNF-alpha induced cell death and metabolism.

  11. These data support a model in which CS-dependent NLRX1 inhibition facilitates MAVS/RHL activation and subsequent inflammation, remodeling, protease, cell death, and inflammasome responses.

  12. Together, these results suggest a novel mechanism for rhinovirus-induced epithelial barrier disruption involving NLRX-1 and mitochondrial reactive oxygen species generation.

  13. NLRX1 and TUFM work in concert to reduce cytokine response and augment autophagy.

  14. Results showed that missense mutations in transmembrane protein 2 p.Ser1254Asn, interferon alpha 2 p.Ala120Thr, its regulator NLR family member X1 p.Arg707Cys, and complement component 2 p.Glu318Asp were associated with chronic hepatitis B.

  15. Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3.

  16. NLRX1 attenuated IFN-I production & promoted autophagy during viral infection cells. NLRX1 interacts with TUFM.

  17. NLRX1 interacts directly with RNA and suggestts a role for NLRX1 in recognition of intracellular viral RNA in antiviral immunity.

  18. the presence of NLRX1 is required for optimal chlamydial growth and reactive oxygen species production

  19. function of NOD-like receptors in the antiviral response [REVIEW]

  20. identification of NLRX1 as a check against mitochondrial antiviral responses--an intersection of three ancient cellular processes: NLR signalling, intracellular virus detection and the use of mitochondria as a platform for anti-pathogen signalling

Mouse (Murine) NLR Family Member X1 (NLRX1) Interaktionspartner

  1. Data suggest that Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1) acts as an important regulator of the cisplatin-elicited ototoxity.

  2. NLRX1 function extends to the control of hepatocyte energy metabolism via the restriction of mitochondrial fatty acid-dependent OXPHOS and enhancement of glycolysis.

  3. NLRX1 suppresses tumorigenesis and reveals new genetic pathways involved in the pathobiology of histiocytic sarcoma

  4. Nlrx1-/- mice exhibited significantly larger brain lesions and increased motor deficits following controlled cortical impact injury

  5. role in control of mitochondrial activity and prevention of oxidative stress and apoptosis in tissue injury

  6. this in vitro studies show that NLRX1-deficient T cells have a greater ability to differentiate into an inflammatory phenotype and possess greater proliferation rates

  7. NLRX1 sequesters the DNA-sensing adaptor STING from interaction with TBK1, which is a requisite for IFN-1 induction in response to viral DNA.

  8. NLRX1 diminishes Tumor Necrosis Factor-alpha-induced activation of both Akt- and NF-kappaB-dependent pathways. Since Akt was shown to be essential for Tumor Necrosis Factor-alpha-mediated activation of NF-kappaB it is likely that the primary effect of NLRX1 is at the level of C-Akt proein signaling.

  9. NLRX1 attenuated Apc(min/+) colon tumorigenesis, cellular proliferation, NF-KappaB, mitogen-activated protein kinase, signal transducer and activator of transcription 3 activation, and interleukin 6 levels.

  10. NLRX1 may relate to hair cell maturity, hearing formation and maintenance, and promote hair cell apoptosis through JNK pathway

  11. The regulatory role of NLRX1 in mechanisms of host tolerance employed by macrophages to respond to Helicobacter pylori infection.NLRX1 modulates innate immune responses to Helicobacter pylori infection.

  12. Nlrx1 may play an important role in neurodegenerative diseases, where necrosis is a prominent factor.

  13. These data support a model in which CS-dependent NLRX1 inhibition facilitates MAVS/RHL activation and subsequent inflammation, remodeling, protease, cell death, and inflammasome responses.

  14. The unique capacity of NLRX1 to regulate the cellular sensitivity toward intrinsic versus extrinsic apoptotic signals suggests a critical role for this protein in numerous physiological processes and pathological conditions.

  15. NLRX1 enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein, as well as preventing mitochondrial-induced apoptosis

  16. Analysis of the macrophage and microglial populations indicates that NLRX1 reduces activation during both active and passive EAE models

  17. does not participate in the negative regulation of MAVS-dependent antiviral responses

  18. NLRX1 attenuated IFN-I production & promoted autophagy during viral infection. NLRX1 interacts with TUFM.

  19. study identifies a previously unrecognized role for NLRX1 in the negative regulation of TLR-induced NF-kappaB activation by dynamically interacting with TRAF6 and the IKK complex

  20. NLRX1 interacts with TRAF6 and inhibits NF-kappaB activation

NLRX1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the NLR family. Alternative splicing has been observed at this gene locus and two transcript variants, encoding distinct isoforms, have been identified.

Genbezeichner und Symbole assoziert mit NLR Family Member X1 (NLRX1) ELISA Kits

  • NLR family member X1 (NLRX1) Antikörper
  • NLR family member X1 (nlrx1) Antikörper
  • NLR family member X1 (Nlrx1) Antikörper
  • BC034204 Antikörper
  • CLR11.3 Antikörper
  • DLNB26 Antikörper
  • NOD5 Antikörper
  • NOD9 Antikörper
  • NOD26 Antikörper
  • RGD1311293 Antikörper

Bezeichner auf Proteinebene für NLR Family Member X1 (NLRX1) ELISA Kits

NLR family member X1 , NLR family, X1 , NOD-like receptor X1 , caterpiller protein 11.3 , nucleotide-binding oligomerization domain protein 26 , nucleotide-binding oligomerization domain protein 5 , nucleotide-binding oligomerization domain protein 9 , nucleotide-binding oligomerization domain, leucine rich repeat containing X1 , nucleotide-binding domain and leucine-rich repeat containing

489370 Canis lupus familiaris
539974 Bos taurus
100518678 Sus scrofa
703981 Macaca mulatta
100031223 Monodelphis domestica
100071383 Equus caballus
100303450 Ictalurus punctatus
100407954 Callithrix jacchus
100483796 Ailuropoda melanoleuca
100606930 Nomascus leucogenys
79671 Homo sapiens
270151 Mus musculus
315599 Rattus norvegicus
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