anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) Antikörper

The protein encoded by NLRP6 binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NLRP6 171389 P59044
NLRP6 101613 Q91WS2
NLRP6 171390 Q63035
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Top anti-NLRP6 Antikörper auf antikoerper-online.de

Showing 10 out of 78 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB NLRP6Antibody (N-term) (ABIN657452) western blot analysis in human placenta tissue lysates (35 µg/lane). This demonstrates the NLRP6 antibody detected the NLRP6 protein (arrow). All lanes : Anti-NLRP6 Antibody (N-term) at 1:4000 dilution Lane 1: Human placenta tissue lysate Lane 2: HL-60 whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: U266B1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 99 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:4000 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert IHC (p) Formalin-fixed and paraffin embedded mouse intestine tissue labeled with Rabbit Anti-NALP6 Polyclonal Antibody, Unconjugated (ABIN2559652) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat kidney tissue labeled with Rabbit Anti-NALP6 Polyclonal Antibody, Unconjugated (ABIN2559652) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$317.90
Details
Maus Kaninchen Unkonjugiert WB Anti-NLRP6 Antibody at 1:2000 dilution + mouse heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 97 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Maus PE FACS Detection of NLRP6/NALP6 in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human NLRP6/NALP6 PE-conjugated Monoclonal Antibody. To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$201.14
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Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 4 bis 8 Tage
$522.50
Details
Human Maus Unkonjugiert CyTOF, FACS Detection of NLRP6/NALP6 in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human NLRP6/NALP6 Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$238.43
Details
Maus Kaninchen Unkonjugiert WB Western Blot at 1:2000 dilution + mouse heart lysate Lysates/proteins at 20 ug per lane. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemical staining of bioptic sections of small intestine using anti-NLRP6/NALP6 (human), mAb (Clint-1)  at 1:500 dilution. Method: A) Epithelial tissues which express NLRP6 (positive control) (black arrows) and connective tissues which do not express NLRP6 (negative control) (red arrows) are stained using Clint-1. B) Control confirming non-reactive specificity of the secondary antibody without Clint-1. 100 μg Anmelden zum Anzeigen 5 bis 8 Tage
$572.06
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$527.03
Details
Human Kaninchen HRP IHC (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$416.90
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Weitere Antikörper gegen NLRP6 Interaktionspartner

Human NLR Family, Pyrin Domain Containing 6 (NLRP6) Interaktionspartner

  1. this review discuss recent findings related to NLRP6 activity, while highlighting outstanding questions and future perspectives in elucidating its roles in health and disease

  2. Data suggest that mRNA/protein levels of NLRP6 are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 provides docking site to facilitate interaction between TAB2/3 and TRIM38 in RA synoviocytes in response to TNFalpha. (NLRP6 = ; TAB2/3 = transforming growth factor-b-activated kinase 1-binding protein 2/3; TRIM38 = tripartite motif 38)

  3. Our results revealed an association between NLRP6/AVR and ADM loci with male essential hypertension, suggesting the existence of sex-specific NLRP6/AVR and ADM variants affecting male susceptibility to essential hypertension.

  4. We will focus on NLRP6 and NLRP12.

  5. NLRP6 is a newly characterized member of this family that inhibits NF-kappaB and MAP-kinase dependent immune signaling to hamper anti-microbial defense.

  6. Studies identify AVR/NAVR as key receptors involved in blood pressure regulation and sex-specific modulation of renal water homeostasis, cognitive function, and anxiety-like behavior.

  7. AVR is distinct from Nalp6/PYPAF5 based on different mRNA and protein sizes, subcellular localization, and tissue-specific expression patterns.

  8. The dual AngII/AVP receptor gene N119S/C163R variant exhibits sodium-induced dysfunction and cosegregates with salt-sensitive hypertension in the Dahl salt-sensitive hypertensive rat model.

  9. This publication deals with the rat ortholog of the human NLRP6 gene.

  10. This publication deals with the rat ortholog of the human NLRP6 gene.

  11. A. actinomycetemcomitans enhances NLRP3 and reduces NLRP6 inflammasome expression.

  12. PYPAF5 functions in immune cells to coordinate the transduction of pro-inflammatory signals to the activation of NF-kappaB and pro-caspase-1

Mouse (Murine) NLR Family, Pyrin Domain Containing 6 (NLRP6) Interaktionspartner

  1. NLRP6 knockout (KO) mice were protected against pulmonary S. aureus infection as evidenced by their higher survival rate and lower bacterial burden in the lungs and extrapulmonary organs. In addition, NLRP6 KO mice displayed increased neutrophil recruitment following infection, and when neutrophils were depleted the protective effect was lost.

  2. Clostridium butyricum may exert a beneficial action on visceral hypersensitivity of irritable bowel syndrome (IBS) by inhibiting low grade inflammation of colonic mucous through its action on nod-like receptor pyrin domain-containing protein 6 (NLRP6).

  3. NLRP6 is important for suppressing the development of spontaneous colitis in the Il10 (-/-) inflammatory bowel disease model and NLRP6 deficiency results in the enrichment of Akkermansia muciniphila.

  4. these data reveal a previously unappreciated role for NLRP6 in inflammatory monocytes, which are recruited after dextran sodium sulfate-induced intestinal injury to promote barrier function and limit bacteria-driven inflammation

  5. this study shows that Nlrp6-dependent Inflammasomes do not shape the commensal gut microbiota composition

  6. this review discuss recent findings related to NLRP6 activity, while highlighting outstanding questions and future perspectives in elucidating its roles in health and disease

  7. Study identified a set of microbiota-modulated metabolites whose integrative activity drives NLRP6 inflammasome activation and downstream epithelial IL-18-induced anti-microbial peptide secretion, thereby providing favorable conditions for WT microbiota colonization.

  8. Nlrp6 contributes to recovery from peripheral nerve injury by dampening inflammatory responses independently of IL-1beta and inflammasomes

  9. These data demonstrate that Nlrp6 functions with Dhx15 as a viral RNA sensor to induce IFN-stimulated genes , and this effect is especially important in the intestinal tract.

  10. Study demonstrates that NLRP6 is important in maintaining autophagy in the intestinal epithelium, a process previously shown to be critically important in intestinal granule exocytosis pathway.

  11. Exposure of mice to stress inhibits NLRP6 and alters the composition of the gut microbiota, leading to intestinal inflammation.

  12. Studies identify AVR/NAVR as key receptors involved in blood pressure regulation and sex-specific modulation of renal water homeostasis, cognitive function, and anxiety-like behavior.

  13. AVR is distinct from Nalp6/PYPAF5 based on different mRNA and protein sizes, subcellular localization, and tissue-specific expression patterns.

  14. The dual AngII/AVP receptor gene N119S/C163R variant exhibits sodium-induced dysfunction and cosegregates with salt-sensitive hypertension in the Dahl salt-sensitive hypertensive rat model.

  15. This publication deals with the rat ortholog of the mouse Nlrp6 gene.

  16. This publication deals with the rat ortholog of the mouse Nlrp6 gene.

  17. results reveal NLRP6 as a negative regulator of inflammatory signalling, and demonstrate a role for this NLR in impeding clearance of both Gram-positive and -negative bacterial pathogens

  18. NLRp6 function in maintaining intestinal homeostasis to prevent the development of aberrant inflammation and tumor development within the colon.

  19. Data show that absence of NLRP6 accelerated colitis-associated tumor growth in mice.

  20. Study shows that deficiency of NLRP6 in mouse colonic epithelial cells reduces IL-18 levels & altered fecal microbiota with expanded bacterial phyla Prevotellaceae & TM7; this altered microbiota is associated with a colitogenic phenotype.

NLRP6 Antigen-Profil

Protein Überblick

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation.

Genbezeichner und Symbole assoziert mit NLRP6

  • NLR family pyrin domain containing 6 (NLRP6) Antikörper
  • NLR family, pyrin domain containing 6 (Nlrp6) Antikörper
  • AI504961 Antikörper
  • Avr Antikörper
  • CLR11.4 Antikörper
  • Nalp6 Antikörper
  • Navr Antikörper
  • Navr/Avr Antikörper
  • NLRP6 Antikörper
  • PAN3 Antikörper
  • Pypaf5 Antikörper

Bezeichner auf Proteinebene für NLRP6

NLR family, pyrin domain containing 6 , NACHT, leucine rich repeat and PYD containing 6 , NLR family pyrin domain-containing protein 6 , NACHT, LRR and PYD domains-containing protein 6-like , NACHT, LRR and PYD containing protein 6 , NACHT, LRR and PYD domains-containing protein 6 , PYRIN-containing APAF1-like protein 5 , angiotensin II/vasopressin receptor , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6 , NACHT/LRR/pyrin domain-containing protein 6 , non-angiotensin-vasopressin receptor , angiotensin/vasopressin receptor , dual angiotensin II/vasopressin receptor

GENE ID SPEZIES
466301 Pan troglodytes
483394 Canis lupus familiaris
505101 Bos taurus
720741 Macaca mulatta
100414562 Callithrix jacchus
100469211 Ailuropoda melanoleuca
100519245 Sus scrofa
171389 Homo sapiens
101613 Mus musculus
171390 Rattus norvegicus
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