NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa Proteine (NDUFA1)

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. Zusätzlich bieten wir Ihnen NDUFA1 Antikörper (65) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NDUFA1 54405 O35683
Ratte NDUFA1 NDUFA1 363441  
NDUFA1 4694 O15239
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Top NDUFA1 Proteine auf antikoerper-online.de

Showing 6 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Escherichia coli (E. coli) Human GST tag NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) (AA 1-70), (full length) protein (GST tag) 1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$1,842.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Chinese Hamster His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,082.67
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Hefe Bonobo His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,082.67
Details

NDUFA1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
,

Weitere Proteine zu NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) Interaktionspartnern

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) Interaktionspartner

  1. In an X-chromosome linked model for partial Complex I deficiency, Ndufa1 mutant males displayed reduced respiratory exchange and produced less body heat.

  2. Species-specific and mutant MWFE proteins effect on the assembly of a functional mammalian mitochondrial complex I.

Human NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) Interaktionspartner

  1. The gene signature of OPA1 (zeige OPA1 Proteine), CTSA (zeige CTSA Proteine), NDUFA1, STK10 and PRDX1 (zeige PRDX1 Proteine) was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls.

  2. Fanconi anemia complementation group A (zeige FANCA Proteine) mutants show defective respiration through Complex I, diminished ATP production and metabolic sufferance with an increased AMP (zeige APRT Proteine)/ATP ratio.

  3. Heterozygous mutation in the X chromosomal NDUFA1 gene in a girl with complex I deficiency

  4. Mutations in the NDUFA1 gene is linked to a delayed mitochondrial network recovery in OXPHOS disorders.

  5. Species-specific and mutant MWFE proteins effect on the assembly of a functional mammalian mitochondrial complex I.

  6. A family-based association study finds that the NDUFA1 gene is unlikely to harbor a major visual loss susceptibility locus for Leber hereditary optic neuropathy.

  7. Suppression of NDUFA1 expression could represent a key pathogenic mechanism in the development of basal cell carcinoma

  8. Two novel p.Gly8Arg and p.Arg37Ser hemizygous mutations in NDUFA1 were identified in two unrelated male patients presenting with Leigh's syndrome and with myoclonic epilepsy and developmental delay.

  9. hypothesize that the novel G32R mutation in NDUFA1 is causing complex I deficiency either by itself or in synergy with additional mtDNA variants

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) Interaktionspartner

  1. subunit MWFE is required for assembly into complex I of seven hydrophobic subunits encoded in the mitochondrial genome

NDUFA1 Protein Überblick

Protein Überblick

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.

Genbezeichner und Symbole assoziert mit NDUFA1

  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (Ndufa1)
  • NADH:ubiquinone oxidoreductase subunit A1 (Ndufa1)
  • NADH:ubiquinone oxidoreductase subunit A1 (NDUFA1)
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (NDUFA1)
  • 1810049F12Rik Protein
  • CI-MWFE Protein
  • MWFE Protein
  • RGD1560955 Protein
  • ZNF183 Protein

Bezeichner auf Proteinebene für NDUFA1

CI-MWFE , NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) , NADH dehydrogenase 1 alpha subcomplex, 1 , NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 , NADH ubiquinone oxidoreductase subunit MWFE , NADH-ubiquinone oxidoreductase MWFE subunit , complex I-MWFE , Complex I-MWFE , NADH ubiquinone oxidoreductase NDUFA1 , NADH oxidoreductase subunit MWFE , NADH:ubiquinone oxidoreductase (complex 1) , complex I MWFE subunit , type I dehydrogenase

GENE ID SPEZIES
54405 Mus musculus
363441 Rattus norvegicus
100689328 Cricetulus griseus
4694 Homo sapiens
481033 Canis lupus familiaris
327673 Bos taurus
100983914 Pan paniscus
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