anti-Myoferlin (MYOF) Antikörper

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. Zusätzlich bieten wir Ihnen Myoferlin Kits (8) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MYOF 26509 Q9NZM1
MYOF 226101 Q69ZN7
MYOF 309499  
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Top anti-Myoferlin Antikörper auf antikoerper-online.de

Showing 10 out of 19 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-FER1L3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  MCF7 cell lysate. MYOF is strongly supported by BioGPS gene expression data to be expressed in MCF7 Host:  Rabbit  Target Name:  MYOF  Sample Type:  Hela  Antibody Dilution:  1.0ug/ml  MYOF is strongly supported by BioGPS gene expression data to be expressed in HeLa 100 μL 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$581.17
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), IP, WB Anti-MYOF / Myoferlin antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μL 11 bis 14 Tage
$639.83
Details
Human Maus Unkonjugiert ELISA, IHC, WB   100 μg 6 bis 7 Tage
$509.40
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using MYOF antibody. 200 μL 12 bis 14 Tage
$438.90
Details
Human Maus Unkonjugiert ELISA, WB FER1L3 polyclonal antibody (A01), Lot # 060529JCS1. Western Blot analysis of FER1L3 expression in human stomach. Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 bis 12 Tage
$305.71
Details
Human Kaninchen Unkonjugiert WB FER1L3 antibody used at 1 ug/ml to detect target protein. 50 μg 9 bis 11 Tage
$449.29
Details
Human Maus Unkonjugiert IHC, WB   100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IF, IHC, WB   100 μL 11 bis 16 Tage
$743.29
Details
Human Kaninchen Unkonjugiert ELISA, IF/ICC, IHC, WB   50 μL 11 bis 16 Tage
$412.19
Details

Am meisten referenzierte anti-Myoferlin Antikörper

  1. Human Polyclonal MYOF Primary Antibody für ICC, IF - ABIN4337241 : Volakis, Li, Ackerman, Mihai, Bechel, Summerfield, Ahn, Powell, Zielinski, Rosol, Ghadiali, Kniss: Loss of myoferlin redirects breast cancer cell motility towards collective migration. in PLoS ONE 2014 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Myoferlin Interaktionspartner

Human Myoferlin (MYOF) Interaktionspartner

  1. The observed mitochondrial fission induced by myoferlin depletion led to a decrease of cell proliferation.

  2. Myoferlin is a general component of cancer cell derived exosomes from different breast and pancreatic cancer cell lines.

  3. the cleavage of myoferlin, yielding a membrane-associated dual C2 domain 'mini-myoferlin', is reported.

  4. A novel regulator, myoferlin, of ADAM12 is discovered in HeLa cells and this protein increases ADAM12 expression level, stability, and its enzymatic activity, leading to the reduction of its substrate, E-cadherin, which plays important roles in the regulation of cell adhesion and tumor metastasis.

  5. Data show myoferlin depletion did not affect STAT3 transcription factor (STAT3) phosphorylation, but completely blocked STAT3 translocation to nucleus.

  6. This study is the first to report robust age associations for DNA methylation in MYOF and DDO, both of which have plausible functional roles in aging

  7. Results demonstrate for the first time that nuclear myoferlin expression independently predicts poor clinical outcome in OPSCC patients.

  8. Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer.

  9. MYOF regulates cell adhesions and cell-substrate adhesion strength and may account for the high degree of motility in invasive breast cancer cells.

  10. These data provide the first evidence of myoferlin expression in solid human and mouse tumors.

  11. Data indicate that dysferlin, otoferlin, and myoferlin do not merely passively adsorb to membranes but actively sculpt lipid bilayers.

  12. High myoferlin expression is associated with breast cancer.

  13. The effect of myoferlin on the expression of ZO-1 in airway epithelial cells indicates its role in membrane fusion events that regulate cell detachment and apoptosis within the airway epithelium.

  14. suggest a novel role of MYOF in breast tumor cell invasion and a potential reversion to an epithelial phenotype upon loss of MYOF

  15. MYOF plays a previously unrecognized role in cancer cell invasion.

  16. myoferlin forms a complex with dynamin-2 and VEGFR-2, which prevents CBL-dependent VEGFR-2 polyubiquitination and proteasomal degradation.

  17. solution structure of the inner DysF domain of the dysferlin paralogue myoferlin, which has a unique fold held together by stacking of arginine and tryptophans, mutations that lead to clinical disease in dysferlin

  18. interaction of myoferlin with EHD2 identifies molecular overlap between the endocytic recycling pathway and the machinery that regulates myoblast membrane fusion

  19. In trophoblastic cells, there was a positive correlation between cell fusion and increased dysferlin expression but not myoferlin expression.

  20. These data describe a new role for myoferlin in receptor-dependent endocytosis and an overlapping role for myoferlin-dynamin 2-caveolin 1 protein complexes in membrane fusion and fission events.

Mouse (Murine) Myoferlin (MYOF) Interaktionspartner

  1. data demonstrate myoferlin's critical role in lysosomal exocytosis by phagocytes

  2. these findings demonstrate the importance of dysferlin and myoferlin for transverse tubule function and in the genesis of muscular dystrophy.

  3. These data provide the first evidence of myoferlin expression in solid human and mouse tumors.

  4. Myoferlin gene knockdown not only decreases lipid vesicle fusion in EC but also attenuates Vascular Endothelial Growth Factor (VEGF) Receptor-2 (VEGFR-2) expression.

  5. increased expression in myofibres after muscle injury and in a mouse model of muscular dystrophy

  6. IGF1 receptor recycling is required for normal myogenesis and myoferlin is a critical mediator of postnatal muscle growth mediated by IGF1

  7. Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains. (myoferlin)

  8. myoferlin plays role in the maturation of myotubes and the formation of large myotubes that arise from the fusion of myoblasts to multinucleate myotubes.

  9. myoferlin forms a complex with dynamin-2 and VEGFR-2, which prevents CBL-dependent VEGFR-2 polyubiquitination and proteasomal degradation.

  10. interaction of myoferlin with EHD2 identifies molecular overlap between the endocytic recycling pathway and the machinery that regulates myoblast membrane fusion

Myoferlin (MYOF) Antigen-Profil

Protein Überblick

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

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Bezeichner auf Proteinebene für anti-Myoferlin (MYOF) Antikörper

fer-1-like 3, myoferlin , fer-1-like protein 3 , myoferlin , Fer-1-like protein 3

GENE ID SPEZIES
26509 Homo sapiens
226101 Mus musculus
309499 Rattus norvegicus
393849 Danio rerio
513597 Bos taurus
607472 Canis lupus familiaris
700922 Macaca mulatta
100037837 Xenopus (Silurana) tropicalis
100154898 Sus scrofa
100380767 Salmo salar
100484247 Ailuropoda melanoleuca
100541976 Meleagris gallopavo
100595205 Nomascus leucogenys
423805 Gallus gallus
100071199 Equus caballus
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