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MYZAP encodes a protein that is abundantly expressed in cardiac tissue. Zusätzlich bieten wir Ihnen MYZAP Antikörper (10) und viele weitere Produktgruppen zu diesem Protein an.
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Cardiac overexpression of Myozap results in cardiomyopathy with hypertrophy and left ventricular dilation.
Reveal myozap as a previously unrecognized component of a Rho-dependent signaling pathway that links the intercalated disc to cardiac gene regulation.
This gene encodes a protein that is abundantly expressed in cardiac tissue. The encoded protein localizes to intercalated discs in cardiomyocytes and functions as an activator of Rho-dependent serum-response factor signaling. Alternate splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstreamstream gene POLR2M (polymerase (RNA) II (DNA directed) polypeptide M).
GRINL1A combined protein , GRINL1A complex locus protein 1 , myocardial zonula adherens protein , myozap , GRINL1A upstream protein , myocardial intercalated disc protein , myocardium-enriched Zo-associated protein , myocardium-enriched zonula adherens protein , myocardium-enriched zonula occludens-1-associated protein