Mycn (MYCN) ELISA Kits

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. Zusätzlich bieten wir Ihnen MYCN Antikörper (98) und MYCN Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MYCN 4613 P04198
MYCN 18109 P03966
MYCN 298894 Q63379
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Top MYCN ELISA Kits auf antikoerper-online.de

Showing 5 out of 6 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Ratte 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$779.90
Details
Ratte
0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$946.00
Details
Maus
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$946.00
Details
Huhn
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,095.60
Details

Weitere ELISA Kits für MYCN Interaktionspartner

Human Mycn (MYCN) Interaktionspartner

  1. Results establish evidence that high MYCN amplification can be present in retinoblastoma with or without coding sequence mutations in the RB1 (zeige RB1 ELISA Kits) gene.

  2. USP7 (zeige USP7 ELISA Kits) deubiquitinates MYCN to enhance its stability and transcriptional activity in neuroblastoma (zeige ARHGEF16 ELISA Kits).

  3. The study conducted metabolic profiling of pre-malignant sympathetic ganglia and tumors derived from the TH-MYCN mouse model of neuroblastoma (zeige ARHGEF16 ELISA Kits), that overexpresses human MYCN and compared to non-malignant ganglia from wildtype littermates. These results identify enhanced glutathione biosynthesis as a selective metabolic adaptation required for initiation of MYCN-driven neuroblastoma (zeige ARHGEF16 ELISA Kits).

  4. Many prognostic signatures for neuroblastoma (zeige ARHGEF16 ELISA Kits) are confounded by MYCN amplification.

  5. Increasing MYCN copy number is associated with an increasingly higher rate of unfavorable clinical/biological features, with 11q aberration being an exception. Patients with MYCN gain appear to have inferior outcomes, especially in otherwise more favorable groups.

  6. miR (zeige MLXIP ELISA Kits)-21 enhances chemo-resistance in tongue cancer cells via directly targeting CADM1 (zeige CADM1 ELISA Kits), and an inverse correlation between miR (zeige MLXIP ELISA Kits)-21 and CADM1 (zeige CADM1 ELISA Kits) expression in vivo. MiR (zeige MLXIP ELISA Kits)-21 overexpression is attributed to MYCN-mediated transcriptional regulation, which is also predictive for a worse prognosis in tongue cancer

  7. LMO1 (zeige LMO1 ELISA Kits) is an important oncogene (zeige RAB1A ELISA Kits) that promotes neuroblastoma (zeige ARHGEF16 ELISA Kits) initiation, progression, and widespread metastatic dissemination.

  8. our results identify DOT1L (zeige DOT1L ELISA Kits) as a novel cofactor in N-Myc-mediated transcriptional activation of target genes and neuroblastoma (zeige ARHGEF16 ELISA Kits) oncogenesis. Furthermore, they characterize DOT1L (zeige DOT1L ELISA Kits) inhibitors as novel anticancer agents against MYCN-amplified neuroblastoma (zeige ARHGEF16 ELISA Kits).

  9. CCCTC-binding factor (CTCF (zeige CTCF ELISA Kits)) targets the binding sites within MYCN promoter to facilitate its expression in neuroblastoma (zeige ARHGEF16 ELISA Kits) (NB) cells.

  10. PAX3 (zeige PAX3 ELISA Kits)-FOXO1 (zeige FOXO1 ELISA Kits) collaborates with MYCN during early rhabdomyosarcoma (RMS) tumourigenesis to dysregulate proliferation and inhibit myogenic differentiation and cell death.

Mouse (Murine) Mycn (MYCN) Interaktionspartner

  1. the role of N-myc in mouse lens development, was examined.

  2. Using comparative genomic hybridization, authors found that NCC (zeige SLC12A3 ELISA Kits)-derived NBL (zeige NUMBL ELISA Kits) tumors in mice acquired copy number gains and losses that are syntenic to those observed in human MYCN-amplified NBL (zeige NUMBL ELISA Kits) including 17q gain, 2p gain and loss of 1p36.

  3. a Mycn target gene encoding the miR (zeige MLXIP ELISA Kits) cluster miR-17~92, while most retinoblastomas reemerged without clear genetic alterations in either Mycn or known Mycn targets. This Rb/MYCN model recapitulates key genetic driver alterations seen in human retinoblastoma and reveals the emergence of MYCN independence in an initially MYCN-driven tumor.

  4. The findings reveal a PLK1 (zeige PLK1 ELISA Kits)-Fbw7 (zeige FBXW7 ELISA Kits)-Myc (zeige MYC ELISA Kits) signaling circuit that underlies tumorigenesis and validate PLK1 (zeige PLK1 ELISA Kits) inhibitors, alone or with Bcl2 (zeige BCL2 ELISA Kits) antagonists, as potential effective therapeutics for MYC (zeige MYC ELISA Kits)-overexpressing cancers.

  5. ALKR1275Q cooperated with MYCN in the development of aggressive NB, possibly by downregulating the expression of ECM (zeige MMRN1 ELISA Kits)/BM-associated genes and by conferring malignant potentials to MYCN-expressing cells.

  6. Reuslts show that N-Myc overexpression leads to the development of poorly differentiated, invasive prostate cancer that is molecularly similar to human NEPC.

  7. Thus, this synergistic effect of ZD55-shMYCN in combination with doxorubicin provides a novel therapy strategy for doxorubicin-resistant neuroblastoma (zeige ARHGEF16 ELISA Kits), and is a promising approach for further clinical development.

  8. demonstrate a critical link between Myc (zeige MYC ELISA Kits)/Mycn gene activity and glycolysis in spermatogonial stem cell self-renewal

  9. Loss of N-myc significantly impairs the Sonic hedgehog (zeige SHH ELISA Kits) signaling pathway and disrupts the expression of cell cycle effectors with a significant reduction of Ccnd2 (zeige CCND2 ELISA Kits).

  10. Study shows that ground-state embryonic stem cells express low Myc (zeige MYC ELISA Kits) levels. Deletion of both c-myc (zeige MYC ELISA Kits) and N-myc activity strongly decreases transcription, splicing, and protein synthesis, leading to proliferation arrest; process is reversible and occurs without affecting pluripotency, suggesting that Myc (zeige MYC ELISA Kits)-depleted stem cells enter a state of dormancy.

MYCN Antigen-Profil

Beschreibung des Gens

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Genbezeichner und Symbole assoziert mit Mycn (MYCN) ELISA Kits

  • MYCN proto-oncogene, bHLH transcription factor (MYCN) Antikörper
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) Antikörper
  • v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Mycn) Antikörper
  • MYCN proto-oncogene, bHLH transcription factor (Mycn) Antikörper
  • olfactory receptor 8S1 (LOC515887) Antikörper
  • MYCN proto-oncogene, bHLH transcription factor (mycn) Antikörper
  • MYCN proto-oncogene, bHLH transcription factor S homeolog (mycn.S) Antikörper
  • bHLHe37 Antikörper
  • c-nmyc Antikörper
  • fb57a02 Antikörper
  • MODED Antikörper
  • mycn Antikörper
  • mycn-a Antikörper
  • mycn-b Antikörper
  • mycna Antikörper
  • MYCNOT Antikörper
  • N-myc Antikörper
  • Nmuc1 Antikörper
  • Nmyc Antikörper
  • Nmyc-1 Antikörper
  • nmyc1 Antikörper
  • ODED Antikörper
  • wu:fb57a02 Antikörper
  • XN-myc Antikörper
  • xN-myc1 Antikörper
  • XNmyc Antikörper
  • zgc:85706 Antikörper

Bezeichner auf Proteinebene für Mycn (MYCN) ELISA Kits

N-myc proto-oncogene protein , class E basic helix-loop-helix protein 37 , neuroblastoma MYC oncogene , neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene , oncogene NMYC , pp65/67 , v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived , v-myc myelocytomatosis viral related oncogene, neuroblastoma derived , N-myc protein , neuroblastoma myc-related oncogene 1 , Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc) , Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc) , N-myc-like protein , v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog , MYCN proto-oncogene, bHLH transcription factor S homeolog , v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog S homeolog , v-myc myelocytomatosis viral related oncogene, neuroblastoma derived, a

GENE ID SPEZIES
4613 Homo sapiens
482978 Canis lupus familiaris
421948 Gallus gallus
18109 Mus musculus
298894 Rattus norvegicus
515887 Bos taurus
252851 Danio rerio
380041 Xenopus laevis
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