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Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein.
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SC4MOL is situated within the psoriasis susceptibility locus PSORS9, and may be a genetic risk factor for common skin conditions. [review]
variants in/near SC4MOL, were associated with FI and IR in this cohort of African Amer
human SC4MOL encodes a methyl sterol oxidase that may have a role in psoriasiform dermatitis, microcephaly, and developmental delay
This work identifies a critical role for SC4MOL and NSDHL (zeige NSDHL ELISA Kits) in the regulation of EGFR (zeige EGFR ELISA Kits) signaling and endocytic trafficking and suggests novel strategies to increase the potency of EGFR (zeige EGFR ELISA Kits) antagonists in tumors
Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
C-4 methylsterol oxidase
, C-4 methyl sterol
, sterol-C4-methyl oxidase-like protein
, neuropep 1
, neurorep 1
, sterol-C4-methyl oxidase-like
, methylsterol monooxygenase 1