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The protein encoded by MBD1 is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). Zusätzlich bieten wir Ihnen MBD1 Antikörper (102) und MBD1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Dihydrofolate reductase (zeige DHFR ELISA Kits) and thymidylate synthase (zeige TYMS ELISA Kits) form a complex in vitro and co-localize in normal and cancer cells.
MBD1 (zeige DPEP1 ELISA Kits) may be a tumor suppressor gene in advanced colorectal cancer (CRC (zeige CALR ELISA Kits))and affect the development and metastasis of CRC (zeige CALR ELISA Kits) by regulating 8 tumor suppressor genes through binding with SP1 (zeige PSG1 ELISA Kits).
Our findings imply that reduced stability and enhanced dynamics of MBD1 (zeige DPEP1 ELISA Kits) or MBD6 is the origin of ATP7B (zeige ATP7B ELISA Kits) dysfunction in Wilson disease patients with the G85V or G591D mutation.
Single nucleotide polymorphism in DHFR (zeige DHFR ELISA Kits) gene is associated with Systemic lupus erythematosus.
study concludes polymorphism 63/91 in DHFR (zeige DHFR ELISA Kits) gene promoter can modulate the onset of methotrexate-related adverse effects in rheumatoid arthritis patients
our findings suggest that the identification of DHFR (zeige DHFR ELISA Kits) polymorphisms in the promoter region of the gene may be helpful in tailoring MTX (zeige MTX1 ELISA Kits) doses for ALL pediatric patients on maintenance therapy.
The abundance of dihydrofolate reductase (zeige DHFR ELISA Kits) was statistically significantly increased in rheumatoid arthritis (RA)-patient biopsies compared with controls and correlated with the administered dosage of methotrexate (MTX (zeige MTX1 ELISA Kits)), the most frequently prescribed immunosuppressive drug for RA.
MBD1 (zeige DPEP1 ELISA Kits) regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.
the binding of MBD1 (zeige DPEP1 ELISA Kits) to nucleosomes demonstrates sequence preferences depending on the position of the methyl groups on the nucleosome.
The present study demonstrated that ADAR1 (zeige ADAR ELISA Kits) positively regulates the expression of DHFR (zeige DHFR ELISA Kits) by editing the miR (zeige MLXIP ELISA Kits)-25-3p and miR (zeige MLXIP ELISA Kits)-125a-3p binding sites in the 3'-UTR (zeige UTS2R ELISA Kits) of DHFR (zeige DHFR ELISA Kits), enhancing cellular proliferation and resistance to methotrexate in MCF-7 cells.
MBD1 (zeige DPEP1 ELISA Kits) has a role in neural stem cell maintenance and epigenetic regulation.
MBD1 targets short interspersed nuclear elements, but does not exclude RNA Polymerase III.
We demonstrated the importance of Aire's interaction with the ATF7ip-MBD1 (zeige DPEP1 ELISA Kits) protein complex in maintaining central tolerance
H19 (zeige NCKAP1 ELISA Kits) lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1 (zeige DPEP1 ELISA Kits).
regulatory loop formed by MBD1 (zeige DPEP1 ELISA Kits) and miR (zeige MLXIP ELISA Kits)-195 is an important component of the epigenetic network that controls aNSC fate
MBD1, miR-184, and Numbl form a regulatory network that helps control the balance between proliferation and differentiation of adult neural stem/progenitor cells.
Results indicate that MBD1 (zeige DPEP1 ELISA Kits) can interpret the CpG dinucleotide as a repressive signal in vivo regardless of its methylation status.
These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes.
Mbd1 (zeige DPEP1 ELISA Kits)(-/-) mice exhibit several core deficits associated with autism, including reduced social interaction, learning deficits, anxiety, defective sensory motor gating, depression and abnormal brain serotonin activity.
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
CXXC-type zinc finger protein 3
, methyl-CpG binding domain protein 1 isoform PCM1
, methyl-CpG-binding domain protein 1
, protein containing methyl-CpG-binding domain 1
, the regulator of fibroblast growth factor 2 (FGF-2) transcription
, methyl-CpG-binding protein MBD1
, coiled-coil domain containing 11