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May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
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The MAGE-D4 polyclonal antibody with high specificity and sensitivity has been successfully prepared.
Preoperative serum MAGED4 was significantly higher in esophageal squamous cell carcinoma patients than in controls.
Results suggest that MAGE-D4 overexpression influences tumor progression, and MADE-D4 can be a prognostic marker and a potential molecular target in squamous cell esophageal cancer.
These findings suggest MAGE-D4 may serve as a potentially prognostic biomarker and an attractive target of immunotherapy in colorectal cancer
MAGE-D4 is highly expressed in glioma and can develop specifically humoral response in glioma patients.
MAGED4 (mRNA and protein) is frequently and highly expressed in glioma and is partly regulated by DNA methylation.
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
melanoma antigen family D, 4
, MAGE-D4 antigen
, MAGE-E1 antigen
, melanoma-associated antigen D4